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---------- -----LLFLE YVDLS----- ---------- ---------- ---------- ---------- -MNQFSGIIP PA-I-GN-LT ---------- ---------- ---------- ---------- -------N-L VYLDLSTNQ- ---------- ---------- ---------- ---------- -------I-- ----TG-SIP ST-------- ---------- ---------- ---------- ---------- -LGDL-T-KL NILYLY-SNQ LSGPL-P--A EIGKMK--SL EYLSLWSNN- LS-------- ---------- -----GPIPV TLGDLTELKL LYLYSNQLSG PIPSELGN-- ---------- ---------- ---LK-NLNN -LQLCDN-Q- -------LS- G-SIPSTL-- GDLTK-LNI- ---------- ---------- -LY------- ---------- ---------- ---------- ---------- -L-YSN---- ---------Q LSGP--LPAE ---------- ---------- ---IG----- KMKSLEYLSL WSNNLSG--- ---------- PIPIILGDLT EFNLC----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -DNQLSGSI- PSTLGDLTKL NILYL----- --YSNQLSGP LL-AEI---G K--MKSLE-Y LSLWSNN-LS GPIPITL--- ---------- ---------- ---------- ---------- -----GDLTE LNVLYLYS-- ---------- ------NQLS GPI-PAE--- ---------- ---------- -IGKMKS--- LKYLSLWSNN L------SGP 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---------- ---------- ---------- ---------- --------Q- ---------- ---------- ----LANLKV LVNLNLSH-- -----NGLSG RIPKELESSS GLHDVVLSYN E-L-EGPIPN ---NK-AFIN AS----LE-- --GNK----- ---------- --------GL CGNVAGLQ-- ---------P CER------P ---------- ---------- ---------- ---------- SSM--VKKHS ----MAK--- -----GRKLI LITVFPVMG- ---------- ----ALALLC VF--IGVLFM C--------- NKRR------ ---------- -----RV-R- -DV------- ---------- -----ERRDG ---------- ---------- ---------- -------D-G W--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --------LS IS-------M LDG------- -------K-A LYRDILNAT- EEFDAKF-CI GQGGH-GSVY KVNL--PSL- G-NIAVKRLH ----SSFQN- ---------- -THPKSFINE VRAL----TG I-KHRNIVNL YGYCSK---- ----AQHSFL VYEYVERGSL SSILSN---- ---------- -------EV- ESK---KL-- DW--LKRVNI IKGVAFALSY MHRDCSS-P- IVHRDISSSN VLL----DS- EY-EARIADF GIAKILK--- ---------S DSSNCT---- ----A----- ---------- --------FA GTYGYVAP-- ---------- ---------- ------ELA- Y--------- -TMK---VTQ M-CDVYSFGV LSLEI-VKGK H--------- -------L-- -------GDY ISVLA----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --NSSTI--- ----DPE-Q- ---------- ----LSD--- ---LLDER-L -PYP------ -DDRVK--DV ---------L ----VYIINL ACSCLLETPK SRP------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---TMPFIS- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -HKLSSM--- ---------- ---------- ---------- ------DARP PIHQK----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- TPI------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC04H1G0433.2 --------MD NMNTN----- --------SA ITLLI-VLFF ---------- ---------- -SLILASV-- ---------- ---------- --------NA VSSSIKTDAE ---------S LLLF-KNMIQ KDPS------ GVL------- --SG-W---- ---------- ---------- -----QLKNN -P-------- -------C-- ---------- ---------- ---------- --------S- WNGVT----- ---------- --------C- -----NS--- LG-------- ---------- ---------- R-VTN----- ---------- ---------- -LDLQQSEL- -----VGE-- ---------- ---------- --VSFSPFNS ---------- -----LDMLT VLNLS----- ---------- ---------- ---------- ---------- -SNSFYVNAS TS-L-TQ-LP Y--------- ---------- ---------- ---------- -------S-L KQLELSFT-- ---------- ---------- ---------- ---------- ------GL-- ----AG-YVP ENF------- ---------- ---------- ---------- ---------- -FAKC-P-NL EYVSLS-FNN ITGSLPQ--N FLLHTD--KL QYLAMDYNN- LT-------- ---------- -----GSI-- ---------- ---------- -SDIKIET-- ---------- ---------- ---CN-SLLR -LDLSGN-Q- -------IMD --SIPSAL-- SNCTT-LQE- ---------- ---------- -LV------- ---------- ---------- ---------- ---------- -L-AEN---- ---------F FSGS--IPTS ---------- ---------- ---FG----- ELISLQRLDL SKNHLSG--- ---------- WIPSEL---- ---------- ---------- ---------- ---------- ---------- ---------- -G-------- ---------- ---------- ----NSCSSL VELKF----- --SNNNITGS IP-NSF---S S--CSSLQ-N LDLSNNN-LT GPFPDSIL-- ---------- ---------- ---------- ---------- -----QNLAS LESLQMSS-- ---------- ------NKIS GSF-PASLSY CKKLRVVDFS SNMINGMIPP DLCSGASS-- LEELRAPDNS L------YGP I-PS-QLS-- QCSQ------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----LKTIDF SLNY------ ---------- ---------- ---------- ---------- --LN------ -G-------- ---------- ---------- ---------- ---SI-PSEL 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GGG--KRSSA ---------- -----ASLAN SIVLGVLIS- ---------- ----IASVCI LI--VWAIAM R--------- ARRR------ ---------- -----EA-EG V-K------- ---------- -----MLSSL S--------- ---------- ---------- --TNYAAS-S WK------ID K--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----EKEPLS IN-------V ATFQRQL--- ------RK-L KFSQLIEAT- NGFSAAS-LI GSGGF-GEVF KATL--KDG- S-SVAIKKLI RLSC------ ---------- -QGDREFMAE METL----GK I-KHKNLVPL LGYCKV---- ----GEERLL VYEFMEYGSL EEMLHGKTR- ---------- ----MPDRR- ------IL-- TW--EERKKI ARGAAKGLCF LHHNCIP-H- IIHRDMKSSN VLL----DN- EM-DARVSDF GMARLIS--- ---------A LDTHLSV-S- ----T----- ---------- --------LA GTPGYVPP-- ---------- ---------- ------EYY- Q--------- -SFR---CTA K-GDVYSFGV VLLEL-LTGK RPTDKEDFG- ---------- -------DTN LVGWV----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --KMKVR--- ---------- -EGK------ ----SME--- ---VIDQE-L -LSVTKGNDE AEVLEV--KE ---------M ----VRYLEI TMQCVEDFAS KRP------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---NMLQVV- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -AMLREL--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------M PGSSS----- ---------- ---------- ---------- ---------- ---------- ---------- ---SNSG--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC01H1G2258.2 --------MA ---------- --------TS NTSLF-FFA- ---------- -------YFL -LVFL-I--- ---------- ---------- --------TP SQSSLRRQAK ---------T LVSLKQA-F- VVSSVPS--- -TL------- --ST-W---- ------N--- ---MSN---- ------YM-S -I-------- -------C-- ---------- ---------- ---------- --------C- WTGIT----- ---------- --------C- -----DD--- TK-------- ---------- ---------- S-VTT----- ---------- ---------- -IDISNLNI- -----SGS-- ---------- ---------- --LS-PDIHE ---------- -----LTR-- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------L RVLNISNN-- ---------- ---------- ---------- ---------- ------LL-- ----GG-NLS WE-------- ---------- ---------- ---------- ---------- -YRKF-N-VL QVLDAY-NNN FTGPL-P--L GVTQLL--QL KYLNFGGNY- FS-------- ---------- -----GK--- ---------- ---------- -IPLSYGS-- ---------- ---------- ---FN-QLEF -LSLAGN-D- -------LH- G-PIPREL-- GNVTS-LRW- ---------- ---------- -LQ------- ---------- ---------- ---------- ---------- -LGYYN---- ---------Q FDEG--IPPE ---------- ---------- ---LG----- KLVNLVHLDL SSCNLTG--- ---------- SIPAEL---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----GNLNML DTLFL----- --QKNQLTGV FP-PQL---G N--LTRLK-S LDISVNE-LT GEIPVDL--- ---------- ---------- ---------- ---------- -----SGLKE LTLLNLFI-- ---------- ------NNLH GEI-PGCI-- ---------- ---------- --AELPK--- LEMLNLWRNN F------TGS I-PS-KLG-- MNGK------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----LVEIDL SSNR------ ---------- ---------- ---------- ---------- --LT------ -G-------- ---------- ---------- ---------- ---LI-PKSL CFGRNLKI-- LILLD----- ---------- ---------N FLFGPLP-D- ---DFGQ--- ---------- --------CR T--------- ---------- ---------- ------LSRV -RM------- ------GQNY LS-GSIPTGF LYLP------ ---------- ---------- -------ELS LVELQNNYIS G-----QLSN ---------- ---------- ---------- ---------- ---------- ---------- EKSSASSKLE ------GLNL SNN-RL-SGA L--------- ---------- --------P- ---------- ------SAFG NY-------- ---------- ---------- ---------- ---------- ---------- ---------- -------SGL -KNLVLTG-- --NGF----- -SGDIPSDI- ---------- ---------- ---------- ---------- ---------- ---------- ---------G R--------- ------L--- ---KSILK-- ---------- ---------- ---------- -------L-D LSRN--NFSG TIPPQIGNC- ---------L SL-TYLDLSQ NQL-SGPI-- ------PV-- ---------- ---------- ---------- ---------- --------Q- ---------- ---------- ----IAQIHI LNYINISW-- -----NHFND SLPAEIGSMK SLTSADFSHN N-L-SGSIPE ---TG-QYLY FN----STSF I-GNP----- ---------- --------YL SGS-DSTP-- ---------- SNI------T --S------- ---------- ---------- -------NSP S-----KL-G ------DGSD NRTKVPTIYK FIFAFGLLF- ---------- -----CSLIF VV--LAI--- ---------- IKTR------ ---------- -----KG-SK N--------- ---------- ---------- ---------- ---------- ---------- ------SN-L W--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -K-------L TAF-QKL--- -------E-F GSEDVL---- QCLKDNN-VI GRGGA-GIVY KGTM--PNG- D-HVAVKK-L GISKG-SHD- ---------- -N---GLSAE LKTL----GK I-RHRYIVRL LAFCSN---- ----KEINLL VYEYMLNGSL GEVLHG---- ---------- -------KN- -GG---QL-- QW--DTRLKI AIEAAKGLSY LHHDCSP-M- IIHRDVKSNN ILL----NS- EL-EAHVADF GLAKYF---- -HNN-----G TSECMS---- ----A----- ---------- --------IA GSYGYIAP-- ---------- ---------- ------EYA- Y--------- -TLK---IDE K-SDVYSFGV VLLEL-ITGR RPVG-N-FGE -------E-- -------GMD IVQWA----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --KTETN--- ----WSKEE- ---------- ----VVK--- ---ILDER-L ---------- -KNVAI--VE ---------A ----MQVFFV AMLCVEEYSI ERP------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 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---------- --------TL WEGVG----- ---------- --------C- -----DD--- NG-------- ---------- ---------- R-VTT----- ---------- ---------- -LWLPSRSL- -----FGN-- ---------- ---------- --IT-PAIAN ---------- -----LSKLS QLSLS----- ---------- ---------- ---------- ---------- -NNRFFGPLP DG-F-FKSFS ---------- ---------- ---------- ---------- -------S-L QIIDLSYN-- ---------- ---------- ---------- ---------- ------RL-- ----SG-RLP ---------- ---------- ------L--- ---------- ---------- -SDRLTS-PI KTVNLS-SNH FNGTI----L SSFLEPAINL ESFDISNNS- FS-------- ---------- -----GP--- ---------- ---------- -IPSFICS-- ---------- ---------- ---YSAAVRV -LDFTSN-D- -------FR- G-QMPQGF-- GSCSS-LVT- ---------- ---------- -LR------- ---------- ---------- ---------- ---------- -A-GFN---- ---------H LSGF--IPDD ---------- ---------- ---IY----- SVSTLQEISL PGNKFSG--- ---------- PIPESI---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----VNLVNL RILAL----- --YGNELTGL IP-QDI---G 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---------- ---------- ---------- ---------T Q--------- ------L--- ---QRLASQE A-ADQVDRSA LELPVFVQPN -NASNQQYNL LSNLPPAI-Y LGNN--NLDG NIPTKIGQL- ---------K YI-HVLDLSK NNF-TGNI-- ------PE-- ---------- ---------- ---------- ---------- --------T- ---------- ---------- ----ISNLTN LEKLDLSA-- -----NNLSG EIPSSLKGLH FLSSFSVAHN N-L-EGPIPT ---GG-QFDT FP----ITSF L-GNP----- ---------- --------GL CGQILQHP-- ---------- CPD------R SGT------- ------TQP- ---------- -------SAV RKT--AKRKI ---------- ---------L IGLILGISF- ---------- ----GIAFTV II--IAFWIF SK-------- ---R------ ---------- -----RI-LP RGD------- ---------- -----AEKN- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- DM-------E IVSYNST--- ---------- ---------- ---------- ---------- ---------- ------SGLS AEIG------ ---------- -K-------- ---------- --DNSMLV-- ---------- -------MLL IYSYMQNGSL DYWLHE---- ---------- -------KT- 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FQ-W-AS--- ---------- ---------- ---------- ---------- ------LR-L LDLSFMGN-- ---------- ---------- ---------- ---------- ------HL-- ----SG-PFP KV-------- ---------- ---------- ---------- ---------- -LTRI-T-TL RN-------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -LSIEGN-K- -------FS- G-TIPPEI-- GNLVH-MEK- ---------- ---------- -LV------- ---------- ---------- ---------- ---------- -L-SSN---- ---------K LTGA--LPAT ---------- ---------- ---LA----- KLTNLTDMRI NDNNFTG--- ---------- KIPKFI---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------S S--WTKIE-K LHIQGCS-LE GPIPSSI--- ---------- ---------- ---------- ---------- -----SFLTS LIDLRISDL- ---------- ------KSGK SGF-PP---- ---------- ---------- -LDNLES--- IKILVLRNCL I------HGE M-PE-YIG-- EMKK------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----LKTLDL SFNS------ ---------- ---------- ---------- ---------- --LS------ -G-------- ---------- ---------- ---------- ---EI-PSTF VHLSKVDF-- IYLTA----- ---------- ---------N KLTGLVP-G- ---WILT--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -----RNKN- ---------- ---------- ---------- ---------- ---------- -IDVSTNNFT WE----TSPF ECPRGN---- ---------- ---------- ---------- ---------- ---------- ---------- -------QNL VESYS-ALGQ ESNKIH---- -----PCLKQ NFPCS--EP- ---------- ----IDQQQY SI-------- ---------- ---------- ---------- ---------- ---------- -----HINCG G--------- -KEVTIKNGT KYTNYEADLE PRGASMYYSR HN-------- ---------- ---------- ---------- ---------- ---------- ------WAFS STGNFMDNDV ESD-VYI--- --NTNVSA-- ---------- ---------- ---------- -------LQN VKAPELELYT TARISPLSLT YYGQCLM-NG NYTVKLHFAE IIF-TNDTS- -----FNS-- ---------- ---------- ---------- ------LG-- --------ER I--------F DVY------- ----LQENLV LKDFNIAKEA GGPG-KPIVK TFTVNVTSHT LKIHFYWAGR G---TTGIPF RGVYGPLISA IS---VVNKF P--------- ---------- ---------- ---------- ---------- ---------- ---------- --------PP L--------- ---------- ----PARLPA HL-------- ---PADQKSK INVGILAGII ---------- ----AGSVFL VL--LIIGIL YKGG-----C L-GE------ ---------- -----NVSTD REL------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --------KG LD-------L QA-------- --GL-----F TLRQIKAAT- KNFDPAN-KI GEGGF-GSVY KGLL--SDG- T-VIAVKQLS AKSK------ ---------- -QGTREFLNE IGMI----SA V-QHPNLVKL YGCCIQ---- ----GNQLLL VYEYMENNCV SRVLFGKGP- ---------- -----IGKM- ------KL-- DW--STRKKI CLGIARGLAY LHEESSL-K- IVHRDIKTSN ILL----DK- DF-NPKISDF GLAKLH---- --------ED DTTHIST--- ----R----- ---------- --------IA GTVGYMAP-- ---------- ---------- ------EYAM R-GY------ -------LTS K-ADIYSYGV VALEI-ISGK SNTNYR---- ----PTED-- -------CVY LLDWA----- 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---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC07H1G1848.2 ---------- ---------- -----M--QM KLLL------ ---------- ---------- --FFLSTF-- ---------- ---------- --------P- LIFALNQDGL ---------Y LQKLKHS-L- SSSDQ----- GVF------- --ST-W---- ------Y-E- ---------- -----NDP-T -P-------- -------C-- ---------- ---------- ---------- --------N- WTGVT----- ---------- --------C- -----NDAGD SP-------- ---------- ---------- S-VVA----- ---------- ---------- -VNLSGASL- -----AGT-- ---------- ---------- --FP-VFLCH ---------- -----LTSLS SLSLS----- ---------- ---------- ---------- ---------- -NNLINSTLP VS-I-SE-CR ---------- ---------- ---------- ---------- -------S-L TYLDLSQN-- ---------- ---------- ---------- ---------- ------LI-- ----GG-TIP DT-------- ---------- ---------- ---------- ---------- -ISDL-P-YL RYLDLS-GCY FSGNI-P--A SFGRFR--QL ETLILTENI- LT-------- ---------- 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--------MI GH-------- ---------- K--MC-GL-- ---------- --------YM KILF-VFAVF A--------- ---------- ------VQNC QGFTDPRDVF ---------A INSLYTS-L- GYP------- L-L------- --PG-W---- ------V--- ---------- -----PYGLD -P-------- -------CGD ---------- ---------- ---------- --------L- WHGVL----- ---------- --------C- -----V---- NS-------- ---------- ---------- N-VTG----- ---------- ---------- -IVLNDSNL- -----GGE-- ---------- ---------- --LS-DGIGS ---------- -----FASII QIDLS----- ---------- ---------- ---------- ---------- -NNHIGGSIP S--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -------NLP ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------V--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------TLKT -LSLSGN-Q- -------LT- G-SIPDNI-- SSLGQ-LTD- ---------- ---------- -LS------- ---------- ---------- ---------- ---------- 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---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -QNLLQ---- ---------- ---------- ---------- ---MI----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC01H1G2156.2 ---------- ---------- ---------- MSSSH-FLSF ---------- ---------- -LFLSLL--- IS-------- ---------- ---------G IFSDLNADRA ---------A LLHLSAA-IK G--------- RTL------- ---R-W---- ------N--- ---------- -----TTNST -P-------- -------C-- ---------- ---------- ---------- --------S- 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ALGVATGIEY LHSLGA--K- VTHGNIKSSN ILL----TH- YY-DAYLSEF GITPLISSTS ---------- ---------- ---------- ---------- --------NS KMTGYYAP-- ---------- ---------- ------EV-T D--------- -IRN---VSQ K-ADVYSFGT ILLEL-LTGK NPS------- --SVINDE-- -------GID LPKWV----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --KCIVEE-- ---------- -RGT------ -----TK--- ---VFDPE-L -IRFQNYDE- --------EQ ---------M ----VSLLHL AISCTSHHPE RRP------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---SMADTT- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -RRIKEIV-- -----IH--- ---------- --------TQ RYTL--ARLI IVEG--EF-- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 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---------- ---------- ---------- -------K-L TKL------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---HLG-SNN LSGSF----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --PASLGN-- ---------- ---------- ---LT-YLQE -LKLSYN-Q- -------LK- G-KLPDSL-- SQMRS-LTL- ---------- ---------- -ID------- ---------- ---------- ---------- ---------- -L-SVN---- ---------Q LC-E--FPLP ---------- ---------- ---LY----- NLSSLKGIGL SYNYFSG--- ---------- NLRSNI---- ---------- ---------- ---------- ---------- ---------- ---------- -G-------- ---------- ---------- ----DAFPEA EKINW----- --GMNSFTRT FP-DSF---A N--ASNLQ-I LDLPGNN-FT GNVPASL--- ---------- ---------- ---------- ---------- -----GKVKN LRWLNVSG-- ---------- ------NQL- GSDEPDNM-- ---------- ------NFIS SLANCSN--- LQN------- ---------- --PF-KLG-- NSQ------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 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---------- -IPRLIYW-- ---------- ---------- ---NE-VLQY -LGLRGN-N- -------LG- G-SLSPDM-- CQLTG-LWY- ---------- ---------- -FD------- ---------- ---------- ---------- ---------- -V-RNN---- ---------S LTGS--IPQN ---------- ---------- ---IG----- NCTAFQVLDL SYNDLTG--- ---------- EIPFNI---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----GFLQ-V ATLSL----- --QGNRLSGQ IP-SVI---G L--MQALA-V LDLSCNM-LS GTIPSIL--- ---------- ---------- ---------- ---------- -----GNLTY TEKLYLHG-- ---------- ------NKLS GSI-PP---- ---------- ---------- ---------- ---------- ---------- -----ELG-- NMTK------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----LHYLEL NDNQ------ ---------- ---------- ---------- ---------- --LT------ -G-------- ---------- ---------- ---------- ---RI-PPEL GKLTELFD-- LNVAN----- ---------- ---------N HLDGPIP-S- ---NLSS--- ---------- --------CT N--------- ---------- ---------- ------LNSL -NV------- ------HGNK LN-GTIPPAF QKLE------ ---------- ---------- -------SMT YLNLSSNNLK G-----PI-- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --------P- ---------- ------IELS RI-------- ---------- ---------- ---------- ---------- ---------- ---------- -------GNV -DTLDLSN-- --NRI----- -SGRIPLSL- ---------- ---------- ---------- ---------- ---------- ---------- ---------G D--------- ------L--- ---EHLLK-- ---------- ---------- ---------- -------L-N LSKN--EING NLPAEFGNL- ---------R SI-MEIDLSS NHL-SGPL-- ------PQ-- ---------- ---------- ---------- ---------- --------E- ---------- ---------- ----LGQLPN LYLLKLEN-- -----NNLSG DV-MSLASCL SLNVLNVSYN N-L-GGNIPT ---GN-NFSR FS----PDSF I-GNP----- ---------- --------DL CGYWLTSP-- ---------- CHA------S HPAE------ ---------- ---------- ---------- ---------- ------R--- -----VSISK AAILGIALG- ---------- ----GLVILL MI--LVAA-- ---------- ---------- ---------- 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------TL-- ----SG-SIP DE-------- ---------- ---------- ---------- ---------- -F-------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -----FQQ-- ---------- ---------- ---CS-SLQS -VSFANN-N- -------LT- G-EIPQSL-- TSCST-LQR- ---------- ---------- -VN------- ---------- ---------- ---------- ---------- -F-SSN---- ---------R LSGP--LPSA ---------- ---------- ---LW----- SLTSLQSLDV SDNLMEG--- ---------- EIPKAI---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----EGLYSL RSINL----- --HKNKFTGW LP-ENI---G N--CVQLK-S IDLSDNL-LN GELPESM--- ---------- ---------- ---------- ---------- -----RRLGF CTNMELRS-- ---------- ------NLLN GQI-PDWI-- ---------- ---------- --AEMKS--- LKVLDLSANN L------SGR I-PT-SMG-- DVSL------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----LKELNL SNNY------ ---------- ---------- ---------- ---------- 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--RGALE--- ---------- -EGR------ ----IEE--- ---CIDGR-L -Q-------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 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---------- ---------- -----VGGGN KDKGKAE--- ---------- ---------- AVVNDG---- ---------- ---------- ---------- ---------- KS-------L VFFGKMA--- ------KN-F NLDDLLKASA E-------VL GKGTF-GTAY KAAL--ESG- I-TLVVKRLR DVT------- ----V----- --PEKEFREK IEDV----GK M-NHENLVPL RAYYYS---- ----RDEKLL VYDYISMGSL SALLHGNK-- ---------- -------GA- -GRT--PL-- NW--ETRAGI ALGAAHGIAY LHAQGP--S- VSHGNIKSSN ILL----TK- SY-EARVSDF GLAQLVGPSS --T------- ---------- ---------- ---------- --------PN RVAGYRAP-- ---------- ---------- ------EV-T D--------- -PRK---VSQ K-ADVYSFGV LLLEL-LTGK APT------- -HSVLNEE-- -------GVD LPRWV----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --QSVVRE-- ---------- -EWT------ -----AE--- ---VFDLE-L -LRYQNV-E- --------ED ---------M ----VQLLQV AVDCTAQYPD RRP------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---SMAEVT- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -TRVEEL--- ---------- ---------- ---------C RMDSGGGDII DNDA------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -----EVQTA ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC01H1G3825.2 --------MV VSR------- ---------- ---------- ---------- ---------- AMIRRILL-- ---------- --------CF LFVLIHVLSI AARTNPDDSA ---------A LQSLKDS-W- Q--------- NVP------- --PN-W---- ------V--- ---------- -----GA--D -P-------- -------CGS ---------- ---------- ---------- --------S- WDGIG----- ---------- --------C- -----R-N-- SR-------- ---------- ---------- --VVS----- ---------- ---------- -ITLSSIRL- -----KGQ-- ---------- ---------- --LS-EDVQG ---------- -----LSELE TLDLS----- ---------- ---------- ---------- ---------- YNKDLTGSLP Q--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -------YIG ---------- ---------- ---------- ---------- ---------- ---RL----- ---------- ------T--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------KLSN -LILAGC-G- -------FS- G-PIPDSI-- GYLTR-LAF- ---------- ---------- -LS------- ---------- ---------- ---------- ---------- -L-NSN---- ---------R FTGS--IPAT ---------- ---------- ---IG----- YLTELHWLDL SDNQIEG--- ---------- NIPVSN---- ---------- ---------- ---------- ---------- ---------- ---------- -GS------- ---------- ---------- NPGLDLLVNT KRFHF----- --GKNQLSGE IPARLF---H S--NMTLT-H LLVENNK-FT GVIPDTL--- ---------- ---------- ---------- ---------- -----GFVQT MKM------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -------LDM SRNE------ ---------- ---------- ---------- ---------- --FNT----- -S-------- ---------- ---------- ---------- ---DF-PSWI PSLQSLTT-- LVMEK----- ---------- ---------T GLQGSVP-A- SLFSLHQ--- ---------- ---------- ---------- ---------- ---------- ------LQTV -IL------- ------RNNK LN-GSLEIES AHSN------ ---------- ---------- -------QLQ LIDVQNNRIE SFTQKLGYPF EIM------- ---------- ----LKGNPF CNKSG--EGT ETYC-IETQQ TGTDSTSLQN CVTIECSSNQ ---------- ---------V SS-------- ---------- --------P- ACKCAFPYVG ELIFRAPSFL NL-------- ---------- ---------- ---------- ---------- ---------- ---------- -------G-- -------N-- --ITT----- -YETLQKSL- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------M--- ---QTFQE-- ---------- ---------- ---------- -------R-Q LPVE--SVSL HNPTIDSDD- ---------- ---NYLVIHL QVF------- ------PS-- ---------- ---------- ---------- ---------- ----S-QES- ---------- ---------- ----FNATGV -AGIGFVL-- -----SRQIF TPPSS----- ---------- --F----GLY ------VFSS DG-----YKN L-AET----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- SSG--SKKSS S--------- --------TG IIIGATVG-- ---------- -----GSVLA IL--ALIIGI Y--------- -AFR------ ---------- -----QK-K- ---------- ---------- -------RAE DA-------- ---------- ---------- ---AKRID-P F-------AS W--------- ---------- ---------- ---------- ---------- ---------- --DSNKHSG- ---------- ---------- ---------- ---------- -A-------V PQLTGARF-- ---------F SFEELKKWT- NNFSETN-DI GCGGY-GKVY RGTL--PNG- E-LVAIKRAL QGS------- ---------A Q-GAREFKSE IELL----SR I-HHKNVVGL AGFCFD---- 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---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --NPYADYAS T--------- -------SAT YEGEN-KGLN HP-------- ---------- ------YT-- ---ESLFV-- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- YSE------- ---------- ---------- ---------- ---------- ---------- ---------- -----A---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC05H1G1139.2 --------MG FVLQS----- ---------- ------FVVL ---------- ---------- -LCFTPAI-- ---------- ---------- --------VC QVTE------ ---------- FVSIDCG--- SASNYTDT-S TGLA------ -----WTS-- ------D-AG MMGQGKPVVV VN---ANVNS -QQYQRRRDF PADSNKYCYT LKTKE--RRR YLVRATFLYG SPA-AEGTYP KFELYLDATK WGTITISESS RIYVNEMIIR APSNSIDVC- ---LCCAT-- TE-------- ---------- SPF------- --IST----- ---------- ---------- -LELRPLNL- ---------- ---------- ---------- -SMYATDYED --NF------ ----YLKVAA RVDFGAQSKE PIRYPDDPYD RIWDSDLKKR PNFLVDVAAG TERINTTKYI DTNTR--EYP PVKV------ ---------- ---------- ---------- ---------- ---------M QTAVVGTKGM LSY------- ---------- ---------- ---------- ------RL-- ----NLDDFP AT-------- ---------- ----ARA--- ---------- ---------- -FAYF-A-EI EDLGMNETRK FKMEH-PYVP DYSNAV---- --VNIAENA- ---------- ---------- ----NGS--- ---------- YTLYE----- --PSYM---- ---------- ---------- ------NITL DFILS----- -------FSF V-KTPDST-R GPLLSAMEI- -CRYVQ--IA TKTDEQ-DVS TLN------- ----A----- ---------- ---------- ------FRSM SL-GSDW--- --------SD EDGDPCVPTQ ---------- ---------- WEWVTCSTTS P-PRITKITL SGKNVTG--- ---------- EIPREL---- ---------- ---------- ---------- ---------- ---------- ---------- -QH------- ---------- ---------- ---------- ---------- ---------- ---------- ---MEGLT-E LWLDGNS-LT GPIP-DMS-- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -----NLV-- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---NLRIIHL ENNK------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -LTGPIP-S- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -YLG------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----GL---- ---------- ---------- --------P- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -----SL--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---LELDVQN NSL-TGEI-- ------PS-- ---------- ---------- ---------- ---------- --------S- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --LLTGKVTF ---KH----- ---E------ --GNP----- ---------- --------NL RPES--KH-- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -----STRYK VILGASIG-- ---------- -----GLVII LV--LFAVSI FF-------L CHFR------ ------T--- -----KV-SH QK-------- ---------- ---GESMRTN AKPSTTCSMA R--------- -------GGS LMDEGV---A YY-------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------I PQSEIEEAT- ENFSK---KI GKGSF-GPVY YGRL--GDG- K-EVAVKTMA DSSS------ ---------- -HGTKQFATE VALL----SR I-HHRNLVPL IGYYED---- ----DHQRML VYEYMHNGTL RDHI-TESTD ---------- -------KK- ------HL-- DW--LARLNT AEDAAKGLEY LHTGCNP-S- IIHRDVKTSN ILL----DI- NM-RAKVSDF GLSR-Q---- -------AEE DLTHVSS--- ---------- ---------- -------VAR GTVGYLDP-- ---------- ---------- ------EYY- ---------- ANQQ---LTE K-SDVYSFGV VLLEL-ISGR KPFSSEEYGA ---------- ------DW-S IVHWA----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --RSLI-R-- ---------- -KGD------ ----VIS--- ---IMDPA-L -VGHVKV--- --------ES ---------V ----WRIAEV AIQCVERHGT SRP------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---RMHEIL- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -SAIQDAIK- -----I---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -------EKG ID-------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------K LSSSGSSKAQ SSRKTLL--- ---------- ----TSFLDV ESPD------ ---------- ---------- ---------- ---------- ---------- ---------- --ISNSS--- ---------- ---------- ---------- ---------- ---------- ---------- --LT------ ---------- ---------- ---------- -----PSAR- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC05H1G1214.2 ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -----MDDGG ---------G ---------- ---G------ TVF------- --SD-W---- ------N--- ---------- -----ENDDT -P-------- -------C-- ---------- ---------- ---------- --------T- WTGIS----- ---------- --------CA NI-SGSSE-- P--------- ---------- ---------- R-VVG----- ---------- ---------- -ITLSGKNL- -----RGY-- ---------- ---------- --LP-SELGT ---------- -----LLYLR RLNLH----- ---------- ---------- ---------- ---------- -GNYIYGSIP DP-L-FN-AT ---------- ---------- ---------- ---------- -------S-L HSIYLYDN-- ---------- ---------- ---------- ---------- ------NI-- ----SG-ILP PS-------- ---------- ---------- ---------- ---------- -VCNL----- ---------- ------P--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------RLQN -LDISDN-S- -------LS- G-TFSKDL-- RNCRQ-LQR- ---------- ---------- -LI------- ---------- ---------- ---------- ---------- -L-ARN---- ---------K FSGE--IPVG ---------- ---------- ---VF----P ELANLEQFDL SSNLFNG--- ---------- SIPEDI---- ---------- ---------- ---------- ---------- ---------- ---------- -G-------- ---------- ---------- ---------- ---------- ---------- ---------- E--LKSLSGT LNLSFNH-FS GRIPKSV--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------G--- ---------- ---------- ---------- ---------- ---------- ---------D L-PL------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----TVSFDL RNNN------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -LSGEIP-Q- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -------TGS FANQGPTAFL N--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --NPLL-CG- F--------- ---------- --------P- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------L--- ---QKNCK-- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -------N-- ---------- ---------- ---------- ---------- --------S- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -------SNN STQVQ----- ------GSSD NEGTN----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -----SRK-- ---------- -----GLKPG 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ALACTEADPD IRP------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---RMKTIS- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -ENIEKV--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----GA---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC03H1G1736.2 ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --M------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- K--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -GNSLLGTIP DL-------- ---------- ---------- ---------- ---------- -------E-- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- DLQDLQSLDL SLNNLSG--- ---------- PIPHFI---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------A N--LTSLL-Y LNLSFNN-LE GEVPI----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -------TGI F-SN------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----LSTYGF VSNS------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- --K------- ---------- ---------- ---------- ---------- ---------- ---------- -LCGGIQ--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -EL------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----HL---- ---------- ---------- -------RP- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- CVYQ------ ---------- ---------- ---------- ---------- ----ETQKTQ KK-------- ----DVLSLK LILTIVFAAS ---------- --FSILALLI VF-------- ---------- LCWR------ ---------- -----RNLKD QPE------- --------P- -----EVRSE SA-------- ---------- ---------- ---------R FY-------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------PN-I SYEELRIAT- GGFSSEN-LI GSGTH----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------LGDY GLVRLVPGFS -------NGS ELHQFSS--- ---------- -L-------- -------GVM GTIGYAAP-- ---------- ---------- ------EYG- M--------- -GSK---VSI L-GDVYSFGI LILEI-FTGR RPTDTL-FQA ---------- -------SSS LHHFV----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --ETALPE-- ---------- ---------- K---VME--- ---ILENKAF -HGEMTS--- -ISTNG--EE YWGNIKKEQM -ECLVGILEI GVACSAESPR DRL------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---TMRQVY- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -SKLTLIRE- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --------KF LGAEDV---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC01H1G0477.2 ---------- ---------- ---------- MGVLQ----- ---------- ---------L CVIFLFLGIC LQAQS----- ---------- ------QNPQ NLICNPKDFK ---------A LEGFVKS-L- E--T------ -VL------- --DF-W---- ------D--- ---------- ----LGNSTN -C-------- -------C-- ---------- ---------- ---------- --------N- LVGVT----- ---------- --------C- -----DS--- -G-------- ---------- ---------- R-VVK----- ---------- ---------- -LELGKRRL- -----NGK-- ---------- ---------- --LS-ESLGN ---------- -----LDELR TLNLS----- ---------- ---------- ---------- ---------- -HNFLKGPVP FT-L-LH-LS ---------- ---------- ---------- ---------- -------K-L EVLDLSNN-- ---------- ---------- ---------- ---------- ------DF-- ----FG---- ---------- ---------- ---------- ---------- ---------- ---------- ---------L FPSSM----N ----LP--LL QVFNISDNS- FE-------- ---------- -----GP--- ---------- ---------- -VPMGICE-- ---------- ---------- ---NSTRVSV -IKMGVN-Y- -------FN- G-SLPVGI-- GNCGS-LEL- ---------- ---------- -FC------- ---------- ---------- ---------- ---------- -L-GSN---- ---------L LSGS--LPDE ---------- ---------- ---LF----- KLPRLTVLSL QENRISG--- ---------- QLSSQI---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----GNLSSL VHLDI----- --CSNGFSGN IP-DVF---D R--LGNLT-Y LSAHSNR-FF GNIPTSL--- ---------- ---------- ---------- ---------- -----ANSGT VSSLSLRN-- ---------- ------NSLG GII------- ----E-LNC- ---------- --SAMVS--- LVSLDLATNG F------RGL V-PE-YLP-- NCQR------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----LQTINL ARNS------ ---------- ---------- ---------- ---------- --FT------ -G-------- ---------- ---------- ---------- ---QL-PESF KNFHSLSS-- LSVSNNSM-- ---------- ---------H NIDAALR--- ---------- ---------- ----ILQHCK N--------- ---------- ---------- ------LSTL -VL------- ------TLNF RD-EVLPTDP NL-------- ---------- ---------- ----QFSELK ALIIANCRLT G-----VVPQ WLRN------ ---------- ---------- ---------- ---------- ---------- -----SSKLQ ------LLDL SWN-RL-TGT L--------- ---------- --------P- ---------- ------PWIG DF-------- ---------- ---------- ---------- ---------- ---------- ---------- -------QFL -FYLDFSN-- --NSF----- -TGEIPKEI- ---------- ---------- ---------- ---------- ---------- ---------- ---------T G--------- ------L--- ---KSLITG- --PVSMNEPS PDFPFFLKRN VSVRGLQYNQ IFSFPPTL-E LGNN--FLTG AILPEFGNL- ---------K RL-HVLDLKS NNL-SGTI-- ------PS-- ---------- ---------- ---------- ---------- --------S- ---------- ---------- ----LSGMAS VENLDLSH-- -----NNLIG NIPSSLVQCS FMSKFSVAYN K-L-SGEIPT ---GG-QFPT FP----ASSF E-GNQ----- ---------- --------GL CGEHGT-P-- ---------- CQN------G S--------- ---------- ---------- -------QVP RDS--VKGKR ---------- -----RKGTV IGMGIGIGL- ---------- ----GTIFLL AL--MYLIVI RA-------- SS-R------ ---------- -----KV--- -VD------- ---------- -----QEKEL DASNRELE-- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------DLGS SL-------V IFFHNKEN-- -----TKE-M CLDDLLKCT- DNFDQSN-IV GCGGF-GLVY KAIL--RDG- R-KVAIKRLS GDYG------ ---------- -QMEREFQAE VESL----SR A-QHPNLVHL QGYCKY---- ----RTDRLL IYSYMENGSL DYWLHE---- ---------- -------KV- DGPA--LL-- DW--DLRLQI AQGAARGLAY LHLACDP-H- ILHRDIKSSN ILL----DE- NF-EAHLADF GLARII---- --------RP YDTHVTT--- ----D----- ---------- --------VV GTLGYIPP-- ---------- ---------- ------EYG- Q--------- -ASV---ATY K-GDVYSFGV VLLEL-LTCK RPMDPC-KPR -------A-- -------SRD LISWV----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --IQMKK--- ---------- -QKR------ ----ETE--- ---VFDPL-I -YDKQHA--- --------KE ---------M ----LLVLEI ACLCLHESPK IRP------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---SSQQLV- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -TWLDNI--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------N TPPDVHV--- ---------- --------F- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC11H1G1045.2 --------MS RIQT------ -----L-HSL QILVI-FL-- ---------- ---------- --KFLVF--- ---------- ---------- ---------- -SNSLSVETE ---------A LLEFKKH-L- VDPL------ NVL------- --ES-W---- ------K-Y- ---------- -----SDS-- -P-------- -------C-- ---------- ---------- ---------- --------K- FYGIQ----- ---------- --------C- -----DKH-- TG-------- ---------- ---------- L-VTE----- ---------- ---------- -ISLDNKSL- -----YGF-- ---------- ---------- --IS-PSISV ---------- -----LQSLT SLVLP----- ---------- ---------- ---------- ---------- -SNFLSGNLP SE-L-AD-CA ---------- ---------- ---------- ---------- -------N-L KVLNVTDN-- ---------- ---------- ---------- ---------- ------NM-- ----NG-TIP D--------- ---------- ---------- ---------- ---------- -LSSL-A-KL EVLDLS-DNC FSGKF-P--A W--------- ---------- ---------- ---------- ---------- ---------- ---------- -----FGK-- ---------- ---------- ---LT-SLVA -LGLGGN-E- -------YDE G-KLPDLF-- GKLKK-VYW- ---------- ---------- -LF------- ---------- ---------- ---------- ---------- -L-ARS---- ---------N LTGQ--IPES ---------- ---------- ---IF----- EMEALGTLDI SKNQISG--- ---------- NFPKSI---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----NKLRNL FKIEL----- --YQNNLTGE LP-VEL---V D--LIHLQ-E IDVSRNQ-LH GTLPKGI--- ---------- ---------- ---------- ---------- -----DNLKN ITVFQIFK-- ---------- ------NNFS GEI-PPGF-- ---------- ---------- --GDLQH--- LNGFAVYNNS F------TGE I-PA-NLG-- RFSP------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----LNSIDI SENK------ ---------- ---------- ---------- ---------- --FS------ -G-------- ---------- ---------- ---------- ---AF-PKYL CQNNNLQN-- LLAVE----- ---------- ---------N SFTGEFP-D- ---NYAS--- ---------- --------CK T--------- ---------- ---------- ------LMRL -RV------- ------SQNQ LS-GRIAEGL WGLP------ ---------- ---------- -------EVT MIDFSDNNFT G-----TVSP GIGA------ ---------- ---------- ---------- ---------- ---------- -----ATKLN ------QLVL SNN-RF-AGE L--------- ---------- --------P- ---------- ------KELG KL-------- ---------- ---------- ---------- ---------- ---------- ---------- -------TQL -ERLYLDN-- --NEF----- -SGIIPSEL- ---------- ---------- ---------- ---------- ---------- ---------- ---------G S--------- ------L--- ---KQISS-- ---------- ---------- ---------- -------L-Y LEKN--SLSG SIPSELGEF- ---------P RL-ANLNLAS NLL-TGNI-- ------PN-- ---------- ---------- ---------- ---------- --------S- ---------- ---------- ----LSMMAS LNSLNLSS-- -----NKLSG SIPTSLDNLK -LSSLDLSNN Q-L-TGRVPT ---D--LLTV GG----ETAF I-GNK----- ---------- --------GL CVDQSIRNVR RN---SSIGA CS-------- ---------- ---------- ---------- ---------- GKA--AQEVF ---------- ------MKSK LVVFCIVLL- ---------- ----SLAVLM GV--FMLVSY ---------- WKYK------ ---------- -----CN-AE ADS------- ---------- -----EKCLG H--------- ---------- ---------- --SNGMNP-K W--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -K-------L ESF-QHV--- -------E-L DVDEIC---- D-VGEDK-LV GSGGT-GKVY RLDL--KKGC G-TVAVKQLW K--------- ---------- GNEVKVLTRE MDIL----GK I-RHRNIVKL --YASLM--- ---REGSNML VFEYLPNGNL FEALHRE--- ---------- ------VKA- GKT---EL-- DW--YQRYKI AVGTAKGIAY LHHDCVP-P- IIHRDIKSTN ILL----DE- EY-EAKVSDF GVAKVS---- -EISS---RV --SEFS---- ----C----- ---------- --------FA GTHGYLAP-- ---------- ---------- ------EIA- Y--------- -TSR---VTE K-SDVYSFGV VLLEL-VTGR KPIEEA-YG- -------E-- -------GKD LVYWA----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --STHLN--- ----DKGSV- ---------- -----LN--- ---ILDQK-V -VSE------ -LVQD----D ---------M ----IKVLRI SALCTTKLPN LRP------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---SMKEVV- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -NMLVDA--- ---------- ---------- ---------- --------EP ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC04H1G2516.2 --------MV P--------- ---------- -KIFY-FL-- ---------- ---------- -MFFTLF--- ---------- ---------- ---------T VTFASVEEAT ---------A LLKWNAN-V- LSQNN----- SLL------- --AS-W---- ------TL-- ---------- ------STDA -C-------- -------R-- ---------- ---------- ---------- --------G- WYGVI----- ---------- --------C- -----FN--- -G-------- ---------- ---------- R-VNK----- ---------- ---------- -INITNVGV- -----VGI-- -----LHD-- ---------- --FP---FSS ---------- -----LLFLE YVDLS----- ---------- ---------- ---------- ---------- -MNQFSGIIP PA-I-GN-LT ---------- ---------- ---------- ---------- -------N-L VYLDLSTNQ- ---------- ---------- ---------- ---------- -------I-- ----TG-SIP ST-------- ---------- ---------- ---------- ---------- -LGDL-T-KL NILYLY-ENQ LSGPL-P--A EIGKMK--SL EYLSLCSNN- LS-------- ---------- -----GPIPV TLGDLTELKL LYLYSNQLSG PIPRELGS-- ---------- ---------- ---LE-NLNN -LQLCDN-Q- -------LT- G-SIPITL-- GDLTK-LNI- ---------- ---------- -LY------- ---------- ---------- ---------- ---------- -L-YEN---- ---------Q LSGP--IPEE ---------- ---------- ---IG----- KMKSLEYLSL WSNNLSG--- ---------- PIPVTLGDLT ELKLLYLYSN QLSGPILAEI GKMKSLKYLS LWGNKLSGPI PVTLGDLTEL NVLYLNSNQL SGPIPREL-G NLKNLNNLQL YENQLSGSI- PSTLGDLTKL NILYL----- --YENQLSGP LP-AEI---G K--MKSLE-Y LSLWSNN-LS GPIPVTL--- ---------- ---------- ---------- ---------- -----GDLTE LNVLYLYS-- ---------- ------NQLS GPI-PAE--- ---------- ---------- -IGKMKS--- LKYLTLRGNK L------SGP I-PS-ELG-- NLKN------ ---------- -----LTRLE ---LSYNQLT GLVPVS---- ---------- ---------- ---------- ---------- ----FGNLRN LQQLNLAANE LSGSIPKEFA YLDNLVLLSM SSNH------ ---------- ---------- ---------- ---------- --F------- SG-------- ---------- ---------- ---------- ---HL-PEWL CKDGKLEI-- FIVNG----- ---------- ---------N KLTGPIP-R- ---SLSK--- ---------- --------CS S--------- ---------- ---------- ------FKRV -RF------- ------NNNS FT-GDLSETF GIYP------ ---------- ---------- -------ELL FIDLSDNDFH G-----ELSS NWGKC----- -------KNL IDLRVARNNI SGSIPPEIGN VKGLLGLDLS SNHLIGQIPK EFGK-LTSLV ------KLSM QNN-NI-SGY I--------- ---------- --------P- ---------- ------EELG SL-------- ---------- ---------- ---------- ---------- ---------- ---------- -------TKL -ESLDLSY-- --NRL----- -NGSIPKCI- ---------- ---------- ---------- ---------- ---------- ---------- ---------G D--------- ------F--- ---VHLFQ-- ---------- ---------- ---------- -------L-N LSNN--KFGQ NIPKDIGRI- ---------T QLNV-LDLSY NLL-VGDI-- ------PP-- ---------- ---------- ---------- ---------- --------Q- ---------- ---------- ----LANLKV LVNLNLSH-- -----NGLSG RIPKELESSS GLHDVVLSYN E-L-EGPIPN ---NK-AFIN AS----LE-- --GNK----- ---------- --------GL CGNVAGLQ-- ---------P CER------P ---------- ---------- ---------- ---------- SSM--VKKHS ----MAK--- -----GRKLI LITVFPVMG- ---------- ----ALVLLC VF--IGVLFM C--------- NKRR------ ---------- -----RV-R- -DV------- ---------- -----ERRDG ---------- ---------- ---------- -------D-G W--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --------LS IS-------M LDG------- -------K-A LYRDILNAT- EEFDAKF-CI GQGGH-GSVY KVNL--PSL- G-NIAVKRLH ----SSFQN- ---------- -THPKSFINE VRAL----TG T-KHRNIVNL YGYCSK---- ----AQHSFL VYEYVERGSL SSILSN---- ---------- -------EV- ESK---KL-- DW--LKRVNI IKGVAFALSY MHRDCSP-P- IVHRDISSSN VLL----DS- EY-EARIADF GIAKILK--- ---------P DSSNCT---- ----A----- ---------- --------FA GTYGYVAP-- ---------- ---------- ------ELA- Y--------- -TMK---VTQ M-CDVFSFGV LSLEI-IKGK H--------- -------L-- -------GEY ITMLA----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --DSSTI--- ----DPE-Q- ---------- ----LSN--- ---LLDER-L -PYP------ -EDRVK--EA ---------L ----VFIIKL ACSCLLETPK SRP------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 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---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- WLPYLVNLDL SSNSFSG--- ---------- SIPPEF---- ---------- ---------- ---------- ---------- ---------- ---------- -IN------- ---------- ---------- ---------- ---------- ---------- ---------- ---CKFLN-T LILNDNK-LT GSIPFEIG-- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -----RLD-- ---------- ---------- ---------- ---------- ---------- R--------- ---------- ---------- ---------- ---------- ---------- ---------- ----LKRFSV SNNG------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -LSGSIP-D- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -DL------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 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---------- ---------- ---------- -L-NLN---- ---------N FIGP--IPAS ---------- ---------- ---VG----- NLSKLRWLDL ADNKLSG--- ---------- PLPVSH---- ---------- ---------- ---------- ---------- ---------- ---------- -GS------- ---------- ---------- TPGLDMLVHT KHFHL----- --GRNQFSGE IPDQLF---S S--NMTLK-H LLLEQNQ-LT GNIPPSL--- ---------- ---------- ---------- ---------- -----GLVQT LEVVRLDR-- ---------- ------NSLD GTI-PSTL-- ---------- ---------- --KSLTL--- MSDLFLSNNK F------TGP L-P--NLA-- GMNA------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----LNYLDM SNNT------ ---------- ---------- ---------- ---------- --FSS----- -A-------- ---------- ---------- ---------- ---DF-PQWF STLQSLTT-- LVMEN----- ---------- ---------T QLQGQIP-S- TLFSLFQ--- ---------- ---------- ---------- ---------- ---------- ------LQTL -NL------- ------RGNK IN-GTLNIAS NYSS------ ---------- ---------- -------QLK LIDLQNNSID SYTVRPGFPF QII------- ---------- ----LMHNPV CYE----EGS EEYC-GNSQT NFGYSTPQDN CLKTQCSSDQ ---------- ---------I LS-------- ---------- --------P- TCKCAYPYTG DLFFRAPSFS DL-------- ---------- ---------- ---------- ---------- ---------- ---------- -------T-- -------N-- --TSI----- -YESIQKSM- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------L--- ---SSFSQ-- ---------- ---------- ---------- -------N-Q VPVD--SVSL SNPKKNS-E- ---------- ---YYLVLHL QVF------- ------PF-- ---------- ---------- ---------- ---------- ----G-QDH- ---------- ---------- ----FNRTGI -STIGFAL-- -----SNQTY KPPPN----- ---------- --F----GPF ------FFSG ES-----YNY F-EAG----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- SRG--THKSI T--------- --------NG IIIGATAG-- ---------- -----GAVLL IL--SVIIGV L--------- -VC------- ---------- -----QK-K- ---------- ---------- -------RDQ EA-------- ---------- ---------- ---VRKSN-P F-------AT W--------- ---------- ---------- ---------- ---------- ---------- --DSIKDSG- ---------- ---------- ---------- ---------- -G-------V PQLTGVKC-- ---------F TFEELKKYT- NNFSESN-YI GSGGY-GKVY KGTL--PDG- Q-LIAIKRAE QAS------- ---------K Q-GALEFKTE IEIL----SR F-HHKNVVSL VGFCFR---- ----QGEQML VYEFIPNGSL KESLSGK--- ---------- ---------- -SGI--KL-- DW--KRRLRI ALGAARGLQY LHDHVDP-P- IIHRDIKSNN ILL----DE- RL-NAKVADF GLSKTM---- -------CEP DKGYVST--- ----Q----- ---------- --------VK GTMGYMDP-- ---------- ---------- ------EYY- T--------- -TQQ---LTE K-SDVYSFGV LLLEL-ITAR SPIVRG-K-- ---------- ---------- ---------- ---------- ---------- ---------- ----YI---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --VKELRQAI DKS-KDMYN- ---------- ----IDE--- ---FVDPA-I -PSNMTP--- --------IS ---------F ----RKFVDL AFTCLEDAGA NRP------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---TMGEVV- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -KEIENI--- -----M---- ---------- ---------E IDGL------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --NSCAESRS T--------- -------SVS HEGTS-ATFD HP-------- ---------- ------YSE- ---ESLNR-- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- YNG------- ---------- ---------- ---------- ---------- ---------- ---------- -----VTNSR ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC12H1G0101.2 --------MA PH-------- ---------- KLFFL----- ---------- ---------- VNFFFTFISF T--------- ---------- ---------- ----FSDDST ---------V MSNFLKG-L- SKP------- P-S------- ---G-W---- ---------- ---------- ------DASK -P-------- ------YC-- ---------- ---------- ---------- --------D- WSKVT----- ---------- --------C- -----DKS-- SN-------- ---------- ---------- T-VVT----- ---------- ---------- -IDLESQGL- -----SGV-- ---------- ---------- --LP-PELNQ ---------- -----LSNLK TLSVQ----- ---------- ---------- ---------- ---------- -RNSLSGILP SF---AN-MS ---------- ---------- ---------- ---------- -------N-L AEIYLNDN-- ---------- ---------- ---------- ---------- ------GF-- ----T--SVP QDF------- ---------- ---------- ---------- ---------- -LLGL----- ---------- ------T--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------SLQT -FSISEN-GK -------LS- PWQIPSYL-- IDSNN-LVN- ---------- ---------- -VY------- ---------- ---------- ---------- ---------- -A-SNA---- ---------S LFGV--IPDF ---------- ---------- ---LG----- KFPNLQDLRL SYNNFTG--- ---------- SLPASF---- ---------- ---------- ---------- ---------- ---------- ---------- -GD------- ---------- ---------- SEIKNLWLNN Q--------- ---VKGLSGT ID--VI---S S--MVQLS-Q VWLHANS-FT GPIPN-L--- ---------- ---------- ---------- ---------- -----SKCEN IFDLQLRD-- ---------- ------NDFT GVI-PDS--- ---------- ---------- ---------- ---------- ---------- ------VM-- KLPN------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----LLNISL QNNK------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -LQGPMP-E- ---FRTE--- ---------- ---------- ---------- ---------- ---------- ------VKVE -IE------- ------GTNS FC-------- -LDT------ ---------- ---------- -------PR- PCDSQVMTLL DVAGGFGYPG FLAD------ ---------- ---SWKGNDA CNG------- ---------- ---------- WSHVSCDGSK K--NVDVVTL GKL-RL-SGF IS-------- ---------- --------P- ---------- -------SFA KL-------- ---------- ---------- ---------- ---------- ---------- ---------- -------TSL -RNLLLND-- --NNL----- -TGSIPESL- ---------- ---------- ---------- ---------- ---------- ---------- ---------A A--------- ------L--- ---PMLLT-- ---------- ---------- ---------- -------L-D VSNN--NLSG PVPAFRS-N- ---------- ---VKLINGG NVF-LGKNI- ------SD-- ---------- ---------- ---------- ---------- ----G-GGS- ---------- ---------- -----GGS-- ---------- ---------- --P------- ---------- ---------- --------GS GS-----SSD G-GNS----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- SGG--SKGSS VQ-------- --------PG VVAGVVISV- ---------- ----VIFILV VL--YVSYKC Y--------- -IRR------ ---------- -----RH-K- ---------- ---------- -------RFG R--------- ---------- ---------- -----VQN-P E--------- ---------- ---------- ---------- RSNDMVKPGV --VIG----N GYA---GVPS ELQSQSSGD- ---------- ---------- ---------- -------HSE MP-------I FEGGNVA--- ---------I SFQVLRQVT- NNFSEEN-IL GRGGF-GVVY KGEL--HDG- T-KIAVKRME SGAM------ ---------G TKGMNEFQAE IAVL----TK V-RHRHLVAL LGSCVN---- ----GNERLL VYEYMPQGTL SQHLF----- ---------- -----EWQE- HGCP--IL-- TW--KQRVTI ALDVARGVEY LHSLAQT-S- FIHRDLKPSN ILL----GD- DM-RAKVADF GLVKNA---- -------PDG KY-SVET--- ----R----- ---------- --------LA GTFGYLAP-- ---------- ---------- ------EYA- A--------- -TGR---VTT K-VDVYAFGV VLMEI-ITGR KALDET-LPD -----ERS-- ---------H LVTWL----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --RRVL---- ----VNKDN- ---------- ----LRK--- ---AIDPT-L -DPDEETY-- --------ES ---------I ----CKVAEL AGHCTAREPF QRP------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---DMGHAV- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -NVLAP---- ---------- ---------- ---------- ---LVELWKP TRNEDEDS-- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --------G- ---------- ---------- ---------- ---------- -IDLQ----- -----MSLPQ ILQRWQADEG T--------- -------SRM F-DDISF--- ---------- ---------- ---------- ---SQTHS-- ---------- ---------- ---------- ---------- ---------- ---------S IPSKPSG--- ----FAD--- ---------- ---------T FNS------- ---------- ---------- ---------- ---------- ---------- ---------- -----TDCR- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC06H1G0038.2 --------MS E--------- -----VESHV LLLIV-LL-- ---------- ---------- -NFFILITG- ---------- ---------- -------RLV CGGSIETDKQ ---------M LLNLKSFLKE QNPVDKG--- FKY------- --NH-W---- ------N--- ---------- -----PSDLS -P-------- -------C-- ---------- ---------- ---------- --------R- WPGIS----- ---------- --------C- -----STS-- IN-------- ---------- ---------- R-VTG----- ---------- ---------- -IDLSESNL- -----AGK-- ---------- ---------- --LF-NNFSA ---------- -----MTELN SLDLS----- ---------- ---------- ---------- ---------- -KNTFSESIP SD-L-GW-CR ---------- ---------- ---------- ---------- -------N-L KFLNLSHN-- ---------- ---------- ---------- ---------- ------II-- ----VG---- ---------- ---------- ---------- --ELN----- ---------- -LTGL-N-KL EVLDLT-MNR IHGLMIP--- ---EICD-NL AVANISNNN- FT-------- ---------- ----SGS--- ---------- -GF------- ----EFSH-- ---------- ---------- ---CK-KLKY -LDLSYN-Y- -------LT- ---------- GNLSFGLDM- ---------- ---------- -LNMFS---- ----A----- ---------- ---------- ---------- ---SHN---- ---------N LSGS--LPSW ---------- ---------- ---IF----T QNCSLQ---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --------GS IP-REI---G S--VQSLK-E LCLGSNN-FS SDIPDTL--- ---------- ---------- ---------- ---------- -----SGLNK LVFLDLSR-- ---------- ------NNFG GEI-QEIF-- ---------- ---------- --GKLTQ--- VRFLVLHGNS Y------IGG I-VSSGIP-- NLVN------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----LSRLDL SDNH------ ---------- ---------- ---------- ---------- --FS------ -G-------- ---------- ---------- ---------- ---PL-PVEI SEMKGLEF-- LILAH----- ---------- ---------N QFSGNIP-L- ---EYGD--- ---------- --------LT A--------- ---------- ---------- ------LQAV -DL------- ------SSNR IN-GSIPPSF GKLR------ ---------- ---------- -------PLL WLMLANNSLS G-----EIPS ELGN------ ---------- ---------- ---------- ---------- ---------- -----CSSLL ------WLNL ANN-QL-TGP I--------- ---------- --------P- ---------- ------PQLA SIGADPMPTF LLNRGKEKLT ASPGDCFAMR RWIPADYPPF SFIYPLLTGK SCRILGDKLF MGDGLMPLCE PGSNVRKNQV PGYIQLSD-- --NKL----- -SGEIPPEI- ---------- ---------- ---------- ---------- ---------- ---------- ---------G N--------- ------M--- ---KKMSM-- ---------- ---------- ---------- -------M-H LGAN--EFSG RLPSEIGQ-- ---------A HL-VVLNVSQ NKF-SGEI-- ------PK-- ---------- ---------- ---------- ---------- --------Q- ---------- ---------- ----IGHLKC LLNLDLSF-- -----NNFSG PFPVSFSNLH DLSKFNISYN PYI-YGAVPE ---IG-QLLT FD----KSSF L-GNPLL--- ---------- --------RL PSFMHNSN-- ---------- ---------- ---------- ---------- ---------- ---------- NNT--ERNKN ---DNHK--- ----KPKKVG ALLVIVVLV- ---------- ----LAFLVC GV--MSLLVC LL-------I KVPRGSPG-- -------ILL EDTEGRH-DS PSS------- ---------- -----TNASS SRLCASSSRG SDDV------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -K-------V IRL-DRT--- -------S-F THSDILKAT- WNFSNDR-II GRGGF-GIVY RGVL--PDG- R-EVAVKKLQ REGI------ ---------- -EGEREFRAE MEGLSGNGSG W-PHPNLVTL YGWCLD---- ----GSEKLL VYEYMEGGTL EDFITDRT-- ---------- ---------- ------RF-- AW--KSRIQA AIDVARALVY LHHDCYP-C- IVHRDVKASN VLL----DK- DG-RAKVTDF GLSRVM---- --------IS EHTHVST--- ----M----- ---------- --------VA GTIGYVAP-- ---------- ---------- ------EYG- Q--------- -IMQ---ATT K-GDVYSYGV LAMEL-ATGR HAID------ ------GG-- -------EEC LVEWA----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --TRVMG--- ---------- -HGRKG---- ----FTRAII PVALLVPG-L -VEG------ -------AEE ---------M ----YELLRI GIRCTADTPH DRP------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---NMKQELR ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -ERLVEF--- -------SRV RGWDQYH--- ---------- --------SP RNLLLA---- ---------- ---------- ---------- ---------- ---------- -------LVG ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---EVGELSE IFQW------ ---------- ---KGEVARG LPNWT----- ---------- ---------- -SDDKEHLEE ELSDVLLYLV QLADVC---- ---------- -GLD------ ---------- LGQA---ALT KIVKNAQ--- ---------- ---------- -------KYP V--------- ---------- ------TKPT ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC06H1G2021.2 --------MA RIQK------ -----LQNSL SILAV-FL-- ---------- ---------- ---FLNFF-- ---------- ---------- --------VQ TCKSLTSESE ---------A LLHFKEQ-L- NDPL------ NYL------- --DS-W---- ------K-D- ---------- -----SES-- -P-------- -------C-- ---------- ---------- ---------- --------K- FYGIT----- ---------- --------C- -----DKN-- TG-------- ---------- ---------- L-VIE----- ---------- ---------- -ISLDNKSL- -----SGV-- ---------- ---------- --IS-PSIFS ---------- -----LQSLT SLVLP----- ---------- ---------- ---------- ---------- -SNALSGKLP SE-V-TN-CT ---------- ---------- ---------- ---------- -------S-L KVLNVTGN-- ---------- ---------- ---------- ---------- ------NM-- ----NG-TIP D--------- ---------- ---------- ---------- ---------- -LSKL-T-NL EVLDLS-INY FSGEF-P--S W--------- ---------- ---------- ---------- ---------- ---------- ---------- -----VGN-- ---------- ---------- ---MT-GLVA -LGLGDN-D- -------FVE G-KIPETL-- GNLKK-VYW- ---------- ---------- -LY------- ---------- ---------- ---------- ---------- -L-AGS---- ---------N LTGE--IPES ---------- ---------- ---IF----- EMGALGTLDI SRNQIIG--- ---------- NFSKSV---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----NKLKNL WKIEL----- --FQNKLTGE LP-VEL---A E--LSLLQ-E FDISSNH-MY GKLPPEI--- ---------- ---------- ---------- ---------- -----GNLKK LTVFQVFM-- ---------- ------NNFS GEI-PPGF-- ---------- ---------- --GDMQH--- LNAFSVYRNN F------SGV F-PA-NLG-- RFSP------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----LNSIDI SENK------ ---------- ---------- ---------- ---------- --FT------ -G-------- ---------- ---------- ---------- ---GF-PKYL CQNGNLQF-- LLAIE----- ---------- ---------N SFSGEFP-S- ---TYSS--- ---------- --------CK P--------- ---------- ---------- ------LQRL -RV------- ------SKNQ LS-GQIPSGV WGLP------ ---------- ---------- -------NVF MMDFSDNKFS G-----TMSP EIGA------ ---------- ---------- ---------- ---------- ---------- -----ATSLN ------QLVL SNN-RF-SGE L--------- ---------- --------P- ---------- ------KELG KL-------- ---------- ---------- ---------- ---------- ---------- ---------- -------TQL -ERLYLDN-- --NNF----- -SGAIPSEL- ---------- ---------- ---------- ---------- ---------- ---------- ---------G K--------- ------L--- ---KQISS-- ---------- ---------- ---------- -------L-H LEKN--SFSG TIPSELGEF- ---------P RL-ADLNLAS NLL-TGSI-- ------PN-- ---------- ---------- ---------- ---------- --------S- ---------- ---------- ----LSTMTS LNSLNLSH-- -----NRLTG TIPTSLDNLK -LSSLDLSNN Q-L-SGEVSL ---D--LLTL GG----DKAL A-GNK----- ---------- --------GL CIDQSIR-FS IN---SGLGS CG-------- ---------- ---------- ---------- ---------- GKA--AKHKL ---------- --------NK LVVSCIVLL- ---------- ----SLAVLM GG--LLLVSY ---------- LNYK------ ---------- -----HS-HE VDH------- ---------- -----EEKLE E--------- ---------- ---------- --AKGTNA-K W--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -K-------L ESF-HPV--- -------E-F DADEVC---- D-FDEDN-LI GSGGT-GKVY RLDL--KKGC G-TVAVKQLW K--------- ---------- GIGVKVLTRE MEIL----GK I-RHRNIVKL --YASLM--- ---KEGSNIL VFEYMPNGNL FEALHRE--- ---------- ------IKA- GKP---EL-- DW--YQRYKI ALGAAKGIAY LHHDCYP-P- IIHRDIKSTN ILL----DE- YY-EAKVSDF GVAKVS---- -EISS---RG --SEFS---- ----C----- ---------- --------FA GTHGYMAP-- ---------- ---------- ------EMA- Y--------- -TLR---VTE K-NDIYSFGV VLLEL-VTGR KPIEEA-YG- -------E-- -------GKD LIYWT----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --STHLN--- ----DKESI- ---------- -----NK--- ---VLDQK-V -VSE------ -LVQD----E ---------M ----IKVLRI ATLCTTKLPN LRP------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---SMKEVV- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -NMLVDA--- ---------- ---------- ---------- --------EP L--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------T FRSSSKSEKK GNS------- ---------- ---------- ---------- ---------- -FSEV----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC07H1G2193.2 ---------- ---------- ---------- MVIWE-FLPM ---------- -------SFL CWVFLAYLFC TSLSL----- ---------- ------ETPV Q-TCHPYDLL ---------A LKEIAGN-L- TDGV------ -IL------- --SA-W---- ------S--- ---------- ------NEPN -C-------- -------C-- ---------- ---------- ---------- --------K- WDGVV----- ---------- --------C- -----GNVSA QS-------- ---------- ---------- R-VIR----- ---------- ---------- -LNLSRKGL- -----RGV-- ---------- ---------- --VS-QSLEK ---------- -----LDQLK LLDLS----- ---------- ---------- ---------- ---------- -HNHLEGGLP LD-L-SK-WK ---------- ---------- ---------- ---------- -------Q-L EVLDLSHN-- ---------- ---------- ---------- ---------- ------VL-- ----LGPVLR ---------- ---------- ------V--- ---------- ---------- -FDGLES--I HSLNIS-SNL FTGNF----S EFGEFP--NL VAFNISNNS- FT-------- ---------- -----GS--- ---------- ---------- -FKFEICS-- ---------- ---------- ---FSKKLKV -LDISLN-H- -------LT- G-DLG-GL-- GNCSSLLQQ- ---------- ---------- -LH------- ---------- ---------- ---------- ---------- -V-DSN---- ---------D LGGH--LPDS ---------- ---------- ---LY----- SMTSLEQLSL SANNFSG--- ---------- QLSPQL---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----SKLSKL KSLVL----- --SGNRFHGL LP-NVF---G N--LTLLE-Q LAAHSNK-FS GPLPSTI--- ---------- ---------- ---------- ---------- -----SYLSV LRVLDLRN-- ---------- ------NSLS GPV------- ----D-LDF- ---------- --TKLTS--- LCTLDLATNH F------KGN L-PV-SLS-- S-RE------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----LKIMSL AKNE------ ---------- ---------- ---------- ---------- --FT------ -G-------- ---------- ---------- ---------- ---PI-PENY ANLSSLVF-- LSLSNNSL-- ---------- ---------S NLSGALS--- ---------- ---------- ----VLQHCR N--------- ---------- ---------- ------LSTL -IL------- ------TRNF RG-EEIPKNV S--------- ---------- ---------- ----GFENLM IFALGNCGLD G-----RIPI WLYN------ ---------- ---------- ---------- ---------- ---------- -----CSKLQ ------VLDL SWN-HL-DGE I--------- ---------- --------P- ---------- ------PWIG EM-------- ---------- ---------- ---------- ---------- ---------- ---------- -------EKL -FYLDFSN-- --NSL----- -TGEIPKNL- ---------- ---------- ---------- ---------- ---------- ---------- ---------T D--------- ------L--- ---KSLISPH NYASSLNSPT -GIPLFVKRN QSGSGLQYNQ ASSFPPSI-L LSNN--RLNG TIWPEIGRL- ---------K QL-HVLDLSK NNI-TGTI-- ------PS-- ---------- ---------- ---------- ---------- --------S- ---------- ---------- ----ISNMGN LEVLDLSC-- -----NDLNG SIPASFNKLT FLSKFNVANN H-L-QGAIPT ---GG-QFLS FP----NSSF E-GNP----- ---------- --------GL CGKIIS-P-- ---------- CAA------S NLD------- ------LRP- ---------- -------ASP LAS--SSSRL ---------- -----GRGGI IGITISIGV- ---------- ----GIALLL AV--VLLRVS RR-------- DAGH------ ---------- -----QI--- -GD------- ---------- -----FEEDF SRPPRSSD-- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------TFVP SK-------L VLFQNSD--- -----CKE-L TVADLLKST- NNFNQSN-IV GCGGF-GLVY KAEL--PNG- I-KAAIKRLS GDCG------ ---------- -QMEREFQAE VEAL----SR A-QHKNLVSL QGYCQH---- ----GSDRLL IYSYMENGSL DYWLHE---- ---------- -------RV- DGSS---L-- TW--DIRLKI AQGAAHGLAY LHK--EP-N- IVHRDIKTSN ILL----NE- RF-EAHLADF GLSRLL---- --------HP YDTHVTT--- ----D----- ---------- --------LV GTLGYIPP-- ---------- ---------- ------EYS- Q--------- -TLT---ATF R-GDVYSFGV VLLEL-LTGK RPVEVC-RGK -------N-- -------CRD LVSWV----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --FQLKS--- ---------- -ENR------ ----VEE--- ---IFDTS-I -WDTSYE--- --------RQ ---------L ----LDVLSI ACQCIVQDPR QRP------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---SIDQVV- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -LWLEAI--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------G SVKER----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC04H1G2510.2 --------MV P--------- ---------- -KIFC-FL-- ---------- ---------- -QLFTLF--- ---------- ---------- ---------T VTFASTEEAT ---------A LLKWKAT-F- QNQNN----- SLL------- --AS-W---- ------TL-- ---------- ------SVGD -C-------- -------T-- ---------- ---------- ---------- --------D- WYGVI----- ---------- --------C- -----FN--- -G-------- ---------- ---------- Q-INR----- ---------- ---------- -LNITNAGV- -----IAT-- -----LQD-- ---------- --FP---FSA ---------- -----LPFLE YVDLS----- ---------- ---------- ---------- ---------- -MNQLSGIIP PE-I-GN-LT ---------- ---------- ---------- ---------- -------N-L VYLDLSSNQF SGKIPSQIGS LSKVENLFIF NNHLNGFIPV EIGSMKSLEI LALQNNNL-- ----SG-LIP IT-------- ---------- ---------- ---------- ---------- -LGDL-S-EL TSLHLY-SNQ LSGPI-P--S ELGNLK--NL NDLELSYNK- LS-------- ---------- -----GSIPV TLGDLTELKI LYLHSNQLSG FIPGELGN-- ---------- ---------- ---LK-NLTD -LELSHN-K- -------LS- G-SIPITL-- GDLTE-LKI- ---------- ---------- -FYLHSNQQS GFIPSELGNL KNLNDLQLFH NKLSGSIPIT LGDLGELKSL HL-YSN---- ---------Q LSGP--IPSE ---------- ---------- ---LG----- NLKNLNDLQL SHNKLTG--- ---------- SIPITLGDLG ELKSLHLYSN QLSGPIPSEL GNLKNLNDLQ LSHNKLSGSI PITLGDLTEL NILYLHSNQL SGFIPSEL-G NLKNLNDLQL SHNKLSGSI- PITLADLTEL KILYL----- --HSNQVSSF IP-SEL---G N--LKNLN-D LELCENQ-LT GSIPITL--- ---------- ---------- ---------- ---------- -----GDLRE LKILLLFS-- ---------- ------NQLS GPI-PSELGN LKNLTDLELS HNNLTGSIPI TLGDLGE--- LKRLHLYSNQ L------SGP I-PS-ELG-- NLKNLNDLQL SHNKLSGSIP ITLGDLTELK ILYLHSNQLS GFIPAEIGKM KSLEVLALQS NNLSGPIPIT LGDLTELESL HLYSNQLTGP IPASFGNLRK LQFLYLCANK LSGSIPKELA YLDNLVELIL SENQ------ ---------- ---------- ---------- ---------- --LTGPIPAS FGNLRKLQFL YLRANKLSGS IPKELAYLDN LVELILSENQ FSDHL-PEHL CQGGKLEN-- FTVNS----- ---------- ---------N KLTGPIP-R- ---SFSK--- ---------- --------CS S--------- ---------- ---------- ------FKRV -RL------- ------DNNS FT-GNLSEAF GIYP------ ---------- ---------- -------KLL FINLSDNRFH G-----ELSS KWGKC----- -------KNL TDFRIARNNI SGSIPPEIGN VKGLLGLDLS SNHLIGQIPK EFGK-LTSLV ------NLFL QNN-RI-SGN I--------- ---------- --------P- ---------- ------EDFG SL-------- ---------- ---------- ---------- ---------- ---------- ---------- -------TKL -ESLDLSD-- --NRL----- -NGSIPMCI- ---------- ---------- ---------- ---------- ---------- ---------- ---------V D--------- ------F--- ---VHLFQ-- ---------- ---------- ---------- -------L-N LSNN--KFGQ KIPKEIGRI- ---------T QLNV-LDLSY NLL-VGDI-- ------PP-- ---------- ---------- ---------- ---------- --------Q- ---------- ---------- ----LANLKV LVNLNLSH-- -----NGLSG RIPLELESLT GLQDVVLSYN E-L-EGPIPN ---NK-AFIN AS----LE-- --GNK----- ---------- --------GL CGNVAGLQ-- ---------P CER------P ---------- ---------- ---------- ---------- SSM--VKKHS ----MAK--- -----GCKLT LITVLPVMG- ---------- ----ALVLLC LF--IGVLFM C--------- NKRR------ ---------- -----RV-R- -EV------- ---------- -----ERRDG ---------- ---------- ---------- -------D-G W--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --------LS IS-------M LDG------- -------K-E LYRDILNAT- EEFDAKF-CI GRGGH-GSVY KVNL--PSL- G-NIAVKRLH ----SSFQN- ---------- -THPKSFIKE VRAL----TG I-KHRNIVNL YGYCSK---- ----AQHSLL VYEYVERGSL ASILSN---- ---------- -------EV- ESK---KL-- DW--LKRVNI IKGVAFALSY MHQDCSP-P- IVHRDISSSN VLL----DS- EY-EARIADF GLAKILN--- ---------P DSSNCT---- ----T----- ---------- --------LA GTYGYVAP-- ---------- ---------- ------ELA- Y--------- -TMK---VTQ M-CDVYSFGV LSLEI-VKGK H--------- -------L-- -------GEY ITVLA----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --NSLTI--- ----DPE-Q- ---------- ----LSD--- ---LLYER-L -PYP------ -EDRVK--DV ---------L ----VFIIKL ACSCLLETPK SRP------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---TMHFIS- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -HKLSSM--- ---------- ---------- ---------- ------DACP PIHQR----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- NPH------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC03H1G0200.2 --------MR RRWNVYGIK- ---------- ------LLLL ---------- ---------- -TILILLL-- ---------- ---------- ------EVHE CCTL-NSEGL ---------S LFEFKLN-VY SDPN------ GVL------- --EN-W---- ------N--- ---------- -----ADHCD -P-------- -------C-- ---------- ---------- ---------- --------M- WSGVE----- ---------- --------CM -----DGK-- ---------- ---------- ---------- --VHM----- ---------- ---------- -LNLHGFSL- -----EGT-- ---------- ---------- --LA-SELGN ---------- -----LTYLR SLILS----- ---------- ---------- ---------- ---------- -GNHFFGAIP KE-F-GR-LD ---------- ---------- ---------- ---------- -------M-L EVLDLRDN-- ---------- ---------- ---------- ---------- ------NL-- ----SG---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------T--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------IPAE ---------- ---------- ---IG----- DLQSLRILLI HNNNFEE--- ---------- SVPLEI---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------G K--LHLVT-E LQFDEN---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----LTSA-- FASGTLCI-R KFSHCIWQGS MKPFKTIT-S IIEP------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----IK-CTL LHYL------ ---------- ---------- ---------- ---------- -SFF------ ---------- ---------- ---------- ---------- ---QL-PSP- -GTGIMDD-- ---------- ---------- -------RKD -CSDNLPRL- ---SRPH--- ---------- ---------- ---------- ---------- ---------- -----IIHTI ---------- ----QHQQEI AR-------- --------R- ---------- ---------- ---------- ---------- ------KLAE QSSN------ ---------- ---------- ---------- ---------- ---------- ---------- ------LAAA PAN------- --------IK GPLG------ --------P- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------V-IQ ---------- ---------- ---------- ---------- -------MP- -RSS--GSFR AVPNSDGTH- --------PT NL-------- ---------- PS----PP-- ---------- ---------- ---------- ---------- ---P------ ---------- ---------- ---------- ---------- ---------- ---------- --------QH E-FQDKLHPV G--------- ---Q------ --SAS----- ---------- --------AV KQSPAVKK-- ---------P TNS------- ---------- ------QGPP ---------- ---------- ----AGKSES TW-KY----- ---------- -----VVGIC ---------- ----IGVILL IL--AASVFL IC-------- ---------- ---------- -----RI-RA ART------- ---------- ---------- ---------- -------IG- ---------- ---------P WK-------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------TGLS GQ-------- --LQKAFVTG -----VPK-L NRSELETAC- EDFSN---II TSGDS-YIVY KGTL--SSG- V-EIAVISTT ISSLED---- --------WS MHSETAFRKK IDTF----SR V-NHKNFVNL IGYCEE---- --DEPFTRMM VFEYAPNGTL FEHLHVEEAD ---------- ---------- ------HL-- DW--PARMRT VMGTMYCLQY MH-ELNP-P- VPHCNLNSKS IYL----TD- DY-AAKITEI DFWSELTAKS --------KS SSDD------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- --------LE NSVLPPLADP E-TNVYSLGI LLIEI-ISGK SPYSEE---- ---------- -------KES LLNWA----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 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---------- ---------- --STALP--- ----EHVME- ---------- ----IVDPL- --LLLAEE-E -QNINQDQ-- -ARRVE--EC ---------L ----LSVLEI GLTCSKSSSR DRA------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---PIDTIL- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------S KL-------- ---------- ---------- ---------- -QAIRES--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --------FL TSR------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 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---------- ----STVKLG VVLGLIAGI- ---------- ----VVVVGA VG--FLIFFI VK-------K VVRN------ ---------- -----RDQGY KND------- ---------- -SFAFEKNST LSKT------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -ADGGNARRT MR-------M VSLGLPP--- ------YHVF TLEEMEEAT- NSFDPTN-LV GEGSQ-GQRW ISGP--SEM- S-EIEAEAFT SN-------- ---------- ---------- ---------- --------SA AAHGDD---- ---------- ---------I KAKASTFNWR ---------- -------KR- -----DVL-- KW--PQRMGI TMGIAKGIQY LHTG----G- VTGNDIKLEN VLL----DE- TL-TARISSY NISLPP---- -------KVG SES------- ---------- ---------- ---------- -------PLA GP-------- ---------- ------DHF- T--------- -SAK---EAE K-EDIYQLGI ILLEA-IIGR PINSRS---- ---------- -------EAE DLKLQ----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -------VE- ---------- --TALAES-- ---------- -PSK------ ----LRD--- ---LTDPC-I -RGTFAY--- --------DS ---------L ----KTTVQI AINCLEKEPS RRP------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---SVEDVL- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------W HMQYS----- ---------- ---------- ---------- -IQVQEG--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --------TT NSGNLSGNQS GKLSGKI--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -----SG--- ---------- ---------- -------NLN ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------NKFY ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC06H1G2470.2 --------MS E--------- -----VESHV LLLIV-LL-- ---------- ---------- -NFFILITG- ---------- ---------- -------RLV CGGSIETDKQ ---------M LLNLKSFLKE QNPVDKG--- FKY------- --NH-W---- ------N--- ---------- -----PSDLS -P-------- -------C-- ---------- ---------- ---------- --------R- WPGIS----- ---------- --------C- -----STS-- IN-------- ---------- ---------- R-VTG----- ---------- ---------- -IDLSESNL- -----AGK-- ---------- ---------- --LF-NNFSA ---------- -----MTELN SLDLS----- ---------- ---------- ---------- ---------- -KNTFSESIP SD-L-GW-CR ---------- ---------- ---------- ---------- -------N-L KFLNLSHN-- ---------- ---------- ---------- ---------- ------II-- ----VG---- ---------- ---------- ---------- --ELN----- ---------- -LTGL-N-KL EVLDLT-MNR IHGLMIP--- ---EICD-NL AVANISNNN- FT-------- ---------- ----SGS--- ---------- -GF------- ----EFSH-- ---------- ---------- ---CK-KLKY -LDLSYN-Y- -------LT- ---------- GNLSFGLDM- ---------- ---------- -LNMFS---- ----A----- ---------- ---------- ---------- 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---------- -----CSSLL ------WLNL ANN-QL-TGP I--------- ---------- --------P- ---------- ------PQLA SIGADPMPTF LLNRGKEKLT ASPGDCFAMR RWIPADYPPF SFIYPLLTGK SCRILGDKLF MGDGLMPLCE PGSNVRKNQV PGYIQLSD-- --NKL----- -SGEIPPEI- ---------- ---------- ---------- ---------- ---------- ---------- ---------G N--------- ------M--- ---KKMSM-- ---------- ---------- ---------- -------M-H LGAN--EFSG RLPSEIGQ-- ---------A HL-VVLNVSQ NKF-SGEI-- ------PK-- ---------- ---------- ---------- ---------- --------Q- ---------- ---------- ----IGHLKC LLNLDLSF-- -----NNFSG PFPVSFSNLH DLSKFNISYN PYI-YGAVPE ---IG-QLLT FD----KSSF L-GNPLL--- ---------- --------RL PSFMHNSN-- ---------- ---------- ---------- ---------- ---------- ---------- NNT--ERNKN ---DNHK--- ----KPKKVG ALLVIVVLV- ---------- ----LAFLVC GV--MSLLVC LL-------I KVPRGSPG-- -------ILL EDTEGRH-DS PSS------- ---------- -----TNASS SRLCASSSRG SDDV------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 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---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---DMLIS-- ---------- ---------- ---------- ---------- ---------- --IPSSQ--- ---------- ---------- -------KGS IRSFG----- ---------- --SSRSTSPL L--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC05H1G0971.2 ---------- ---------- ---------- ---------- ---------- ---------- -------MES SSA------- ---------- --------TL SPAGVNYEVV ---------A LTEIKKA-L- HDPY------ NVL------- --DN-W---- ------D--- ---------- -----VNSVD -P-------- -------C-- ---------- ---------- ---------- --------S- 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---------- ---------- ---------- ---------- ---------- ---------- --EASQKLE- T--------- -------PRN RAFEHTP-QR ---------- ---------- ------YSNY VE-DSSL--- ---------- ---------- ---------- ---------- ---------- ---------V EPMELSG--- -----PG--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC03H1G0711.2 --------MG RCCFV----- ---IKWYYHD IPLKA-FLIL ---------- ---------- -CVFFLVHGY AL-------- ---------- --------SS D-----SDKS ---------A LLELKAS-L- LDSS------ GVI------- --SS-W---- ------S--- ---------- -----SRNTD -H-------- -------C-- ---------- ---------- ---------- --------S- WFGVS----- ---------- --------C- -----DSD-- -S-------- ---------- ---------- R-VVA----- ---------- ---------- -LNITGGNL- ------GS-- ---------- ---------- --LSCAKIAQ FPLY------ ----GFGITR VCANN----- ---------- ---------- ---------- ---------- -SVKLVGKVP LA-I-SK-LT ---------- ---------- ---------- ---------- -------E-L RVLSLPFN-- ---------- ---------- ---------- ---------- ------EL-- ----RG-EIP LG-------- ---------- ---------- ---------- ---------- -IWDM-E-KL EVLDLE-GNL ITGSL-P--L EFKGLR--KL RVLNLGFNE- IV-------- ---------- -----GA--- ---------- ---------- -IPNSLSN-- ---------- ---------- ---CL-ALQI -LNLAGN-R- -------VN- G-TIPAFI-- GGFGD-LRG- ---------- ---------- -IY------- ---------- ---------- ---------- ---------- -L-SFN---- ---------K LSGS--IPGE ---------- ---------- ---IG----R SCEKLQSLEM AGNILGG--- ---------- NIPKSL---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----GNCTWL QSLVL----- --YSNLLEEG IP-AEF---G Q--LTELK-I LDVSRNS-LS GRLPSEL--- ---------- ---------- ---------- ---------- -----GNCSK LSILVLSSLW DPLPNVSDSS RTTDEFNFFE GTI-PSEITR LPSLRMIWAP RSTLSGKFPG SWGACDN--- LEIVNLAQNY Y------TGV I-SE-ELG-- SCQK------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----LHFLDL SSNR------ ---------- ---------- ---------- ---------- --LT------ -GQLVE---- ---------- ---------- ---------- ---KL-P--- -----VPC-- MFVFD----- ---------- ------VSGN YLSGSIP--- ---RFSNYS- ---------- --------CA HVVSSGGDPF GPYD-TSSAY -------LAH FTSRSVLETT -SLFGGDGDH AVFHNFGGNN FT-GNLPPSM LTAPEMLGKQ IVYAFLAGSN RFTGPFAGNL FEKCHELKGM IVNVSNNALS G-----QIPE DIGAI----- ---------- ---------- ---------- ---------- ---------- -----CGSLR ------LLDG SKN-QI-GGT V--------- ---------- --------P- ---------- ------PSIG SL-------- ---------- ---------- ---------- ---------- ---------- ---------- -------VSL -VSLNLSW-- --NHL----- -RGQIPSSL- ---------- ---------- ---------- ---------- ---------- ---------- ---------G Q--------- ------I--- ---KDLSY-- ---------- ---------- ---------- -------L-S LAGN--NLVG SIPSSFGQL- ---------H SL-ETLELSS NSL-SGEI-- ------PN-- ---------- ---------- ---------- ---------- --------N- ---------- ---------- ----LVNLRN LTNLLLNN-- -----NNLSG 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---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --CMLLR--- ---------- -QGR------ ----AKE--- ---FFTAG-L -WDSGPH--- --------DD ---------L ----VEVLHL AVVCTVDSLS TRP------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---TMKQVV- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -RRLKQL--- ---------- ---------- ---------- --------QP ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -PSC------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 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---------- ---------- ---------- ---------- ---------- -LNLENN-L- -------LE- G-PLPPNL-- GSLSR-LRI- ---------- ---------- -MF------- ---------- ---------- ---------- ---------- -L-SAN---- ---------N LTGT--IPEN ---------- ---------- ---FS----- NLKNMTDFRI DGTSISG--- ---------- TIPDFI---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------G N--WTKMD-R LDIQGTS-ME GPIPPTL--- ---------- ---------- ---------- ---------- -----SQLKD MTMLRISDL- ---------- ------RGEQ IQF-PN---- ---------- ---------- -LTGLTK--- MRRLTLRNCS I------FGP I-PR-YVG-- AM-P------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----LKLLDL SNNM------ ---------- ---------- ---------- ---------- --LN------ -G-------- ---------- ---------- ---------- ---PI-PDTF ---RQLDFDN MFLGN----- ---------- ---------N ALSGAIP-S- ---WVFS--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -----SDEN- ---------- ---------- ---------- ---------- ---------- -IDLSYNNFT HT----RTP- GCQPST---- ---------- ---------- ---------- ---------- ---------- ---------- -------INL AASYSDTMNT FNNTDS---- -----WCSMK PLSC----P- ---------- ----TEAKYH SL-------- ---------- ---------- ---------- ---------- ---------- -----FINCG G--------- -GRITFEG-- --NDYEEDLT TRGPSYFFSS SDR------- ---------- ---------- ---------- ---------- ---------- ------WAFS SSGVYVGLAN VS---YI--- --ATNRFL-- ---------- ---------- ---------- -------L-N ISGA--DFYN TARLAPNSLK YYGLCLR-GG SYRVQLHFAE IMF-SNDST- -----YSS-- ---------- ---------- ---------- ------LG-- --------RR I--------F DVA------- ----IQGRVV LKDFNIMEEA NGVG-EVIIK DFDDITVSST LEIHLYWTGK G---TNAIPD RGVYGPLISA IS---VTPNF ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -----KTGRR LPVGAVIGIV ---------- ----LASIVV VL--IVLFSL WKKG-----I FGGK------ ---------- 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---------- -IQLNAANL- -----AGE-- ---------- ---------- --LG-DNLAS ---------- -----FSSLK TIDLS----- ---------- ---------- ---------- ---------- -NNHIGGTFP S--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -------SLP ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------V--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------TLQN -IFLSDN-D- -------LA- G-SIPSSL-- SSLSQ-LSA- ---------- ---------- -MS------- ---------- ---------- ---------- ---------- -L-NGN---- ---------Q LTGE--LPDS ---------- ---------- ---FQ----- GLTALVNLDL SSNSFSG--- ---------- ALPSSV---- ---------- ---------- ---------- ---------- ---------- ---------- -G-------- ---------- ---------- ---------- ---------- ---------- ---------- N--LSSLT-T LHVQNNQ-LS GTLDV----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 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---------- ---------- ---------- ---------- ---------- ---------- -----KKKS- ---------- ----FKLREP AILGIVIGGC ---------- ----VLGFLV VA--AVLIMC F--------- --SK------ ---------- -----KE-GK S--------- ---------- ---------- ---------- ---------- ---------- ---GATEK-S I--------- ---------- ---------- ---------- -KKEDIV--- ---------- ---------R KGVSSSQHG- ---------- ---------- ---------- ---------V GN-------L AFFDGCN--- ------LA-F DLEDLLRASA E-------VL GKGTF-GTTY KAAL--EDS- T-TVVVKRLK E-S------- ----V----- --GRKDFEQQ MEVV----GN I-RHENVAPL RAYYYS---- ----KDEKLM VYDFYSQGSA SLMLHAKR-- ---------- -------SA- -DRI--PL-- DW--ETRLRI AIGAARGIAQ IHGQSGG-R- LVHGNIKSSN IFL----NS- QG-FGCISDL GLATIMGPIA -TP------- ---------- ---------- ---------- --------IV RAAGYQPP-- ---------- ---------- ------EV-T D--------- -SRK---VSQ T-TDVYSFGV LILEL-LTGK SPT------- -HATGTSD-- -------IVH LVRWV----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 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---------- ---------- -LV------- ---------- ---------- ---------- ---------- -L-WDN---- ---------Q LSGY--IPKE ---------- ---------- ---LG----- NCTKLELLAL YQNNLVG--- ---------- EIPAAI---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----GKLKSL KRLYL----- --YRNGLNGT IP-RVI---G N--LSSAI-E IDFSENY-LI GDIPIEF--- ---------- ---------- ---------- ---------- -----SQIKG LILLYLFH-- ---------- ------NQLN GVI-PRELSS LRKLERLDLS INYLYGSIPF SFQYLTE--- LVQLQLFQNS L------SGT I-PQ-GLG-- NYSR------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----LWVVDF SNNY------ ---------- ---------- ---------- ---------- --LT------ -G-------- ---------- ---------- ---------- ---GI-PPNI CRNSNLIW-- LNLGS----- ---------- ---------N NLHGVIP-S- ---GVIK--- ---------- --------CD S--------- ---------- ---------- ------LVQL -RL------- ------HGNW LQ-GSFPSDL CKLS------ ---------- ---------- -------NLS 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---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----LWVLDL NNNQ------ ---------- ---------- ---------- ---------- --LT------ -G-------- ---------- ---------- ---------- ---RI-PPFV CQNSNLIL-- LNLAS----- ---------- ---------N KLHGYIP-S- ---GVLK--- ---------- --------CD S--------- ---------- ---------- ------LVQL -RL------- ------NDNR LT-GTFPSEL CKLI------ ---------- ---------- -------NLS AVELGQNKFT G-----PIPP DIKYC----- -------QKL QRLDFSGNSF -NQLPREIGN LTRLVTFNVS ANSLTGPIPP EIRN-CKALQ ------RLDL SKN-RF-TDV I--------- ---------- --------P- ---------- ------DDIG SL-------- ---------- ---------- ---------- ---------- ---------- ---------- -------SQL -ERLLLSE-- --NKL----- -SGKIPAAL- ---------- ---------- ---------- ---------- ---------- ---------- ---------G S--------- ------L--- ---SHLTE-- ---------- ---------- ---------- -------L-Q MGSN--LLSG EIPSELGNL- ---------S GLQIAMDLSN NNL-SGSI-- ------PP-- ---------- ---------- ---------- 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---------- ---------- --------D- WYGVI----- ---------- --------C- -----FN--- -G-------- ---------- ---------- R-INR----- ---------- ---------- -LNITNAGV- -----IGT-- -----LHD-- ---------- --FP---FSS ---------- -----LLFLE YVDLS----- ---------- ---------- ---------- ---------- -MNQLSGIIP PE-I-GN-LT ---------- ---------- ---------- ---------- -------N-L VYLDLSSNQF SGKIPPQIGS LSKVGNLFII NNHLNGFIPV EIGKMKSLEF LGLQRNNL-- ----SG-PIP VT-------- ---------- ---------- ---------- ---------- -LGDL-S-EL TSLHLY-SNQ LVGPI-P--S ELGNLK--SL NNLELSHNN- LS-------- ---------- -----GSIPI SLGQLTELKI LYLHSNQLSG PIPSELGS-- ---------- ---------- ---LK-NLID -MDLSGN-Q- -------LS- G-SIPITL-- GDLTK-LKI- ---------- ---------- -LY------- ---------- ---------- ---------- ---------- -L-SSN---- ---------Q LSGL--IPRE ---------- ---------- ---FG----- NMKNLIELDL SANQLAG--- ---------- SIPITLGDLT ELKILYLYSN QLSGPIPSEL GSLKNLTDMD LSGNQLSSSI PITLGDLTKL KMLYLSSNQL SGLIPREF-R NLKNLIELDL SANQLAGSI- PITVGDLTEL KILYL----- --YSNQLVGP IP-SEL---G N--LKNLN-D LELSHNN-LS GSIPISL--- ---------- ---------- ---------- ---------- -----GQLTE LKILYLYS-- ---------- ------NQLV GPI-PSELEN LKNLNKLELS HNNLSGSIPI SLGQLTE--- LKILYLHSNQ L------FGP I-PS-ELG-- SLKNLIDMDL SGNQLSGSIP ITLGDLTKLK ILYLSSNQLS GLIPRE---- ---------- ---------- ---------- ---------- ----FGNMKN LIELDLSANQ LSSLFPRELG NLKNLIELDL SSNQ------ ---------- ---------- ---------- ---------- --LAGSIPIT LG-------- ---------- ---------- ---------- ---HL-PERL CQGGKLEI-- FTVNS----- ---------- ---------N KLTGPIP-R- ---SLSN--- ---------- --------CS S--------- ---------- ---------- ------LKWV -RF------- ------NNNS FT-GNLSEAF GIHP------ ---------- ---------- -------KLL FINLSDNDFH G-----ELNS KWGKC----- -------KNL TDFRIARNNI SGSIPPEIGN VKGLLGLDLS SNHLIGQIPK EFGK-LTSLV ------NLFL QNN-RI-SGN I--------- ---------- --------P- ---------- ------EDFG SL-------- ---------- ---------- ---------- ---------- ---------- ---------- -------TKL -ESLDLSD-- --NRL----- -NGSIPMCI- ---------- ---------- ---------- ---------- ---------- ---------- ---------V D--------- ------F--- ---VHLFQ-- ---------- ---------- ---------- -------L-N LSNN--KFGQ KIPKEIGRI- ---------T QLNV-LDLSY NLL-VGDI-- ------PP-- ---------- ---------- ---------- ---------- --------Q- ---------- ---------- ----LANLKV LVNLNLSH-- -----NGLSG RIPRELDTLT GLQDVILSYN E-L-EGPIPN ---NK-AFIN AS----LE-- --GNK----- ---------- --------GL CGNVAGLH-- ---------P CEM------P ---------- ---------- ---------- ---------- SSV--VKRHS ----MAK--- -----GRKLI LITVLPVMG- ---------- ----ALVLLC VF--IGVLFM C--------- NKRR------ ---------- -----RV-R- -DV------- ---------- -----ERRDG ---------- ---------- ---------- -------D-G W--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --------LS IS-------M LDG------- -------K-A LYRDILNAT- EEFDAKF-CI GQGGH-GSVY KVNL--PSL- G-NIAVKRLH ----SSFQN- ---------- -THPKSFINE IRAL----TG I-KHRNIVNL YGYCSK---- ----AQHSLL VYEYVERGSL SSILSN---- ---------- -------EV- ESK---KL-- DW--LKRVNI IKGVAFALSY MHQDCSP-P- IVHRDISSSN VLL----DS- EY-EARVADF GLAKILN--- ---------P DSSNCT---- ----T----- ---------- --------LA GTYGYVAP-- ---------- ---------- ------ELA- Y--------- -SMK---VTQ M-CDVYSFGV LSLEI-VKGK H--------- -------L-- -------GEY ITVLA----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --NSLTI--- ----DPE-Q- ---------- ----LSD--- ---LLDER-L -PYP------ -EDRVK--DV ---------L ----VFIIKL ACSCLLETPK SRP------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---TMHFIS- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -HKLSSM--- ---------- ---------- ---------- ------DARP PIHQR----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- NPHEKNVRVH ---------- ---------- -SKTSYGACN VMGTDGLGGH LVA------- ----VLCLIL AGDGGSDGCG V--------- -------GYL VGLASSK--- ---------- ---------- -------LIR FMGCALVWRK KENGW--VGA AAATVLERDV GGRRQQSYCL LPGLR----- -----VRFWV SDFAREE--- -----EDAGS WVLLVF---- ---------- -VVVYIGKSL --GWASEWEE EYYSISIGHE IWVGGYL--- ---------- ----- RHC05H1G0682.2 ---------- ---MS----- -----MFNKL LLVWF-FVV- ---------- -------TLV -LGYVFS--- ---------- ---------- ---------- -----ETELE ---------V LLEIKKSFL- DDPEN----- -VL------- --SN-W---- ------S-D- ---------- -----KNQ-N -F-------- -------C-- ---------- ---------- ---------- --------Q- WSGVS----- ---------- --------C- -----EED-- TL-------- ---------- ---------- K-VVR----- ---------- ---------- -LNLSDCSI- -----SGSIS PSFGFLHDLL HLDLSSNLLS GPIP-PTLSN ---------- -----LSSLQ SLLLY----- ---------- ---------- ---------- ---------- -SNQLTGPIP NE-I-GL-LK ---------- ---------- ---------- ---------- -------N-L QVLRIGDNV- ---------- ---------- --GLTGLIPS SIGDLENLVT LGLASCSL-- ----SG-MIP PELGKLGRVE NMNLQENNLE NG-------- ---------- -------IPA EIGNC-S-SL VAFSVA-VNN LNGSI-P--E ELSMLK--NL QVMNLANNS- LS-------- ---------- -----GQ--- ---------- ---------- -IPTQLGE-- ---------- ---------- ---MN-ELQY -LNLLGN-Q- -------LE- G-SIPKSL-- AKLSN-VRN- ---------- ---------- -LD------- ---------- ---------- ---------- ---------- -L-SGN---- ---------R LTGE--IPGE ---------- ---------- ---FG----- NMDQLQFLVL TSNNLSG--- ---------- SIPKTICS-- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---SNRNSSL EHMML----- --SENQLSGE IP-VEL---K E--CISLK-Q LDLSNNT-LN GSIPVELYEL VELTDLLLNN NTLVGSVSPL IANLTNLQTL ALSHNNFHGN IPKEIGMVEN LEILFLYE-- ---------- ------NQFS GEI-PMEIGN CSRLQMIDFY GNAFSGRIPI TIGGLKE--- LNFIDFRQND L------SGE I-PA-SLG-- NCHQ------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----LKILDL ADNR------ ---------- ---------- ---------- ---------- --LS------ -G-------- ---------- ---------- ---------- ---SV-PATF GYLRALEQ-- LMLYN----- ---------- ---------N SLEGNLP-D- ---ELINLSN LTRINFSHNK LNGSIVSLCS ST------SF LSFDVTNNAF DHEVPPHLGY ---SPFLERL -RL------- ------GNNR FT-GEIPWTL GLIR------ ---------- ---------- -------ELS LLDLSGNELI G-----LIPP QLSLC----- -------RKL THLDLNNNRL YGSIPSWLGN LPLLGELKLS SNKFSGPLPR ELFN-CSKLL ------VLSL EEN-SL-NGT L--------- ---------- --------P- ---------- ------LEIG EL-------- ---------- ---------- ---------- ---------- ---------- ---------- -------KSL -NILNFNK-- --NQL----- -SGPIPSTI- ---------- ---------- ---------- ---------- ---------- ---------- ---------G N--------- ------L--- ---SKLYI-- ---------- ---------- ---------- -------L-R LSGN--NLTG EIPSELGEL- ---------K NLQSILDLSF NNI-IGQI-- ------PP-- ---------- ---------- ---------- ---------- --------S- ---------- ---------- ----VGTLTK LETLDLSH-- -----NHLTG EVPPQVGEMS SLGKLNLSYN N-L-QGKL-- ---DK-QYAH WP----ADAF T-GNP----- ---------- --------HL CGSPLQN--- ---------- CEV------S KSN------- ---------- ---------- -------NR- GSG--LSNS- ---------- ---------T VVIISVIST- ---------- ----TVAIIL ML--LGAALF F--------- KQRR------ ---------- -----EA-FR RGS------- ---------- -----EVNSA --YSSSSSQG QKRPLF---- ---------- -A---SVA-A K--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -R-------D IRW-DDI--- ---------- --MEAT---- NNLSNDF-II GSGGS-GTVY KAEL--FNG- E-IVAIKRIP SKDD------ ---------- LLLDKSFARE IKTL----WR I-RHRHLVRL LGYCNNS--- ---GEGSNVL IYEYMENGSV WDWLHKQP-- ---------- ----ANNNK- RKT---CL-- DW--EARLKI AVGLAQGVEY LHHDCVP-K- IIHRDIKSSN ILL----DS- NM-EAHLGDF GLAKAV---- -HDNY---NS YNTESNL--- ----W----- ---------- --------LA GSFGYIAP-- ---------- ---------- ------EYA- Y--------- -SSK---ATE K-SDVYSMGI VLMEL-VSGR MPTDGS-FG- -------E-- -------DMD MVRWV----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --ESCIE--- ----MSGTV- ---------- ----REE--- ---LIDPV-L -KPL------ -LPNEE--SA ---------A ----LQVLEI ALECTKTAPA ERP------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---SSRKVC- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -DLLLHA--- ---------- ---------- ---------- --------FN DK-------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----VVHSDK ---------- ---------- ---------- ---------- -----MSPDN YV-------- ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC01H1G4282.2 --------MM TI-------- ---------S EHYYS-FWSF ---------- ---------G ---VFFFLLL CP-------- ---------- ---------S F--GLNIDGT ---------L LLSFKYS-VL DDPL------ SVL------- --DN-W---- ------D--- ---------- -----YNDAT -P-------- -------C-- ---------- ---------- ---------- --------L- WNGVT----- ---------- --------CA ------PD-- MF-------- ---------- ---------- R-VIS----- ---------- ---------- -LLLPNSKL- -----IGS-- ---------- ---------- --IP-EELGF ---------- -----IQHLH TIDLS----- ---------- ---------- ---------- ---------- -NNFLNGTLP LS-L-LN-AS ---------- ---------- ---------- ---------- -------E-L QVLSLSNN-- ---------- ---------- ---------- ---------- ------AI-- ----SG-ELT ES-------- ---------- ---------- ---------- ---------- -IGVL----- ---------- ------K--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------SLKV -LNLSVN-A- -------FV- G-NIPQKL-- SSLQN-LKV- ---------- ---------- -VS------- ---------- ---------- ---------- ---------- -L-SKN---- ---------L FSGA--IPSG ---------- ---------- ---F------ --QFVEVLDL SSNLLNG--- ---------- TLPDDF---- ---------- ---------- ---------- ---------- ---------- ---------- -GG------- ---------- ---------- ---------- ---------- ---------- ---------D S--LKYL--- -NFSSNK-LS GLVSPQF--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------AK-- ---------- ---------- ---------- ---------- ---------- ---------K I-PT------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----NATIDL SFNS------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -FTGEIP-E- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -------SLA LSNQKTEFFA G--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --NTDL-CG- K--------- ---------- --------P- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------L--- ---KKLCTI- ---------- ---------- ---------- ---------- ---------- --PSTLSSP- ---------- ---------- ---------- ------PN-- ---------- ---------- ---------- ---------- --------I- ---------- ---------- ---------- ---------- --------TT NPPAIAA--- -------IPK E---INSTPL QDSDG----- ------TTQT AAQNQ----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -----QQH-- ---------- -----GLKPG TIMGIIVGD- ---------- ----LAGVGV LA--IVFLYV YK-------- -LKK------ ---------- -----KN-KA SEA------- ---------- -----TIESS IDKDQKYNK- ---------- -----TPEPS ILVVKEKD-T IFPSW-PCLT INQE------ --------SS DTD---DSKN QESED----- ---------- ---QIEFETE QKNEKNK--- ---------- ---------- ---------- -------KTE RS-------F VMVDG-E--- ------TE-L ELETLLKASA Y-------IL GSSGA-SIVY KAVL--EDG- T-AFAVRRIG ESG------- ----V----- -DKLKDFEQQ IKGI----NK L-RHPNLVRV RGFYWG---- ----DDEKLV IYDYVTNGSL ANIGYKKV-- ---------- -------GS- -SPY--HL-- SY--EVRLKI AKGIARGLTY IHE---K-R- QVHGNIKPSN ILL----TP- DM-EPIISDI GLYGLLHGKN -TSK---PDN SGRHFGSKRS TSSSRDGLND QLVHGSPYIA PAGFVVGCTS P---YHAP-- ---------- ---------- ------ES-L E--------- -SLK---PSP K-WDVYSFGI VLLEL-LTGK ---------- --VFSDRELS Q-----WT-- ----N----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --GSESDD-- ---------- -VDR------ ----VLR--- ---MADVA-I -RADVES-R- --------EE T--------T ----VSLFKL GFSCASLNPQ KRP------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---TMKDAL- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -HVLDKV--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----PGYS-- ---HY----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC10H1G2129.2 --------MA AT-------- ---------- ---------- ---------- ---------- ----RLLL-- ---------- --------CF IIFSSGIDFI YTVTDPRDVT ---------I LRSLKDQ-W- E--------- NTP------- --PS-W---- ------Q--- ---------- -----KSD-D -P-------- -------CGT ---------- ---------- ---------- --------S- WEGVT----- ---------- --------C- -----N-N-- SR-------- ---------- ---------- --VTA----- ---------- ---------- -LGLSTMGL- -----RGK-- ---------- ---------- --LS-GDIGG ---------- -----LTELI SLDLS----- ---------- ---------- ---------- ---------- FNRGLTGSLS P--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -------RIG ---------- ---------- ---------- ---------- ---------- ---DL----- ---------- ------Q--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------KLNI -LILAGC-S- -------FS- G-SIPMEL-- GRLAE-LSF- ---------- ---------- -LA------- ---------- ---------- ---------- ---------- -L-NSN---- ---------N FTGE--IPRT ---------- ---------- ---LG----- NLSKLYWLDL ADNQLTG--- ---------- PIPVST---- ---------- ---------- ---------- ---------- ---------- ---------- -SS------- ---------- ---------- SSGLDLLKKA KHFHF----- --NKNQLSGS IPDILF---S A--DMVLI-H VLFDGNQ-LS GSIPFTL--- ---------- ---------- ---------- ---------- -----GLVQT LEVLRLDR-- ---------- ------NALN GSV-PSNL-- ---------- ---------- --NNLTS--- VVELNLAHNE L------SGP L-P--DLT-- GMNS------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----LNYLDL SNNS------ ---------- ---------- ---------- ---------- --FHK----- -S-------- ---------- ---------- ---------- ---EA-PIWF STLESLTT-- LVIEY----- ---------- ---------G SLHGSVP-Q- KLFALPQ--- ---------- ---------- ---------- ---------- ---------- ------LQQV -KL------- ------RNNA LN-DTLNMGG ISGR------ ---------- ---------- -------QLT LVDLQNNEIS SITLGSGYKN TLI------- ---------- ----LIGNPV CDTA---LGN TNYCQLQQQS AKPYSTSLAN CGSKSCPADQ ---------- ---------K VS-------- ---------- --------PQ SCDCAYPYQG TFYFRGPSFR EL-------- ---------- ---------- ---------- ---------- ---------- ---------- -------S-- -------N-- --DNT----- -FHSLEMSL- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -----WVK-- ---------- ---------- ---------- -------L-D LTPG--SVSL QNPFFNI-D- ---------- ---DYLQVQL ELF------- ------PP-- ---------- ---------- ---------- ---------- ----T-GKY- ---------- ---------- ----FNRSEV -ERIGFSL-- -----SNQTY KPPHE----- ---------- --F----GPY ------YFIA SP-----YTF Q-AE------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -RG---ETSI S--------- --------SR QVIGIATG-- ---------- -----CTILV LL--LVALAI Y--------- -AIQ------ ---------- -----QK-K- ---------- ---------- -------LAE RA-------- ---------- ---------- ---IGLSR-P F-------AS W--------- ---------- ---------- ---------- ---------- ---------- -APSGNDSE- ---------- ---------- ---------- ---------- -G-------A PQLKGARW-- ---------F SYDELKKCT- GNFSERN-EI GSGGY-GKVY RGTL--ANG- Q-VIAIKRAQ HGS------- ---------M Q-GGQEFKTE IELL----SR V-HHKNLVGL VGFCFE---- ----QGEQVL VYEYMPNGSL RENLSGK--- ---------- ---------- -TSI--YL-- DW--KRRLRV ALGSARGLAY LHELANP-P- IIHRDVKSTN ILL----DQ- NL-TAKVGDF GLSKLV---- -------SDS SKGHVST--- ----Q----- ---------- --------VK GTLGYLDP-- ---------- ---------- ------EYY- M--------- -TQQ---LTE K-SDVYSFGV VMLEL-ITAK QPIEKG-K-- ---------- ---------- ---------- ---------- ---------- ---------- ----YV---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --VREMRTAI NKNDEEHYG- ---------- ----LSN--- ---MIDPV-I -RNMPNL--- --------IG ---------F ----TRFVDV AMQCVEEAAA DRP------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---TMSEVV- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -KMLESI--- -----L---- ---------- ---------Q NDGL------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --ETNSTSAS S--------- -------SIT DFGTAIAASR HP-------- ---------- ------YNK- ---EALQRKE I--------- ---------- ---------- -----ND--- ---------- ---------T HAFDYSG--- ---------- ---------- ---------G YTL------- ---------- ---------- ---------- ---------- ---------- ---------- -----PTNVE PK-------- ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC12H1G0510.2 ---------- ---------- -----MSKII FSLFI-FL-- ---------- ---------- --FFIISH-- ---------- ---------- --------GK SQESPNQEKA ---------I LLQLKQHWF- TSPN------ --V------- --TK-W---- ------I-S- ---------- -----SSN-- -H-------- -------C-- ---------- ---------- ---------- --------S- WDGII----- ---------- --------C- -----TQN-- ---------- ---------- ---------- S-VTG----- ---------- ---------- -IQIPFGNI- -----SKP-- ---------- ---------- --IP-NFICD ---------- -----LKNLS FLDFN----- ---------- ---------- ---------- ---------- -HNFIPGNFP D--I-YS-CS ---------- ---------- ---------- ---------- -------N-L EFLDLSYN-- ---------- ---------- ---------- ---------- ------YM-- ----DG-NLP DE-------- ---------- ---------- ---------- ---------- -INRLSS-NL KYLNLT-ANN FNGDI-P--K GIGGLS--QL KVLDLRGNL- FN-------- ---------- -----GS--- ---------- ---------- -FPEEIGE-- ---------- ---------- ---LL-NLEA -LMLSSN-G- -------FAP Q-AIPSRF-- TKLKN-LKF- ---------- ---------- -FW------- ---------- ---------- ---------- ---------- -M-TEA---- ---------H LIGN--IPEY ---------- ---------- ---IG----- NMTSLEFLDL SNNGLSG--- ---------- SIPDGL---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----FQLKNL SIVYL----- --FTNKLSGE IP-QSV---S S---MNLD-V VDLCNNS-LT GKIPEDF--- ---------- ---------- ---------- ---------- -----GKLTK LSGLALFF-- ---------- ------NQLS GEI-PLSI-- ---------- ---------- --GKLSS--- LVSVKLFGNK L------SGE I-PP-DFG-- RFSK------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----LFDFQV SENQ------ ---------- ---------- ---------- ---------- --LV------ -G-------- ---------- ---------- ---------- ---KL-PEGI CNNKALAR-- MVAFG----- ---------- ---------N NLTGELP-S- ---SLGS--- ---------- --------CD S--------- ---------- ---------- ------LRYL -RV------- ------ENNR LS-GEVPDGL WTGK------ ---------- ---------- -------SLS MVLMKNNLLT G-----QLPH RV-------- ---------- ---------- ---------- ---------- ---------- -----ASNLS ------QVDI SNN-KF-SGE L--------- ---------- --------P- ---------- ------AGMG TW-------- ---------- ---------- ---------- ---------- ---------- ---------- -------HNL -SEFKASN-- --NLL----- -SGQIPQEL- ---------- ---------- ---------- ---------- ---------- ---------- ---------T L--------- ------L--- ---PGITK-- ---------- ---------- ---------- -------L-F LDGN--LLSG NFPSNISSW- ---------R TL-VTLNSRK NQL-SGPI-- ------PS-- ---------- ---------- ---------- ---------- --------A- ---------- ---------- ----LGLLPN LIDLDLSS-- -----NQFSG VIPTELGNLR -FTSLNLSSN R-L-SGEIPS ---Q--LENA GF----DKSF L-DNP----- ---------- --------GL CASNPSVEVA S--------- CK-------- ---------- ---------- ---------- ---------- RET--KSDKF ---------- -------PVG LVAALASVA- ---------- ----AVTFLV ----AVLYGL ---------- FVLR------ ---------- -----SH-RK RKQ------- ---------- -----E-SV- ---------- ---------- ---------- -------S-T W--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -K-------Q TSF-HKL--- -------D-F TESDIV---- SNLTENN-II GSGGS-GQVY LVPL--SRSG D-YVAVKRIW RNQRLDHK-- ---------- --HEKQFLAE VQIL----GT I-RHSNIVKL --LCCIF--- ---SEESKLL VYEYMENRSL DIWLHSKNR- ---------- ----LNNAS- RSTPHLVL-- EW--PRRLQI AIGAARGICY MHHDCSP-P- IIHRDVKSSN ILL----DS- QF-NAKIADF GLARML---- -LKPG---D- --NTVT---- ----A----- ---------- --------VA GSFGYIAP-- ---------- ---------- ------EYA- R--------- -KTR---VTE K-IDVYSFGV ILLEL-VTGK EA---N-LGD -------E-- -------DSC LADWA----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --WRHLQ--- ----KGKPM- ---------- ----AD---- ---ALDED-I -KET------ -RYLE----E ---------I ----FIVFKL GIFCTSTFPS SRP------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---TMKEVL- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -QILIQC--- SNSS----PT SGEK------ ---------- --------KN ET-------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------EQDV LPL------- ----LKNS-- ---------- -RSER----- ---------- ---------- ---------- ---------- ---------- ---------- --IEEND--- ---------- ---------- -------DVG L--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -TSII----- ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC11H1G0292.2 ---------- ---------- ---------M SSKIL-FL-F ---------- -------TIS VSIFTLFL-- ---------- ---------- ---------P TNSDIVSDRA ---------T LLSIRSA-LR G--------- RSL------- ---L-W---- ------N--- ---------- -----ITSPT ---------- -------C-- ---------- ---------- ---------- --------S- WPGVI----- ---------- --------C- -----SPD-- KS-------- ---------- ---------- S-VLE----- ---------- ---------- -LHLPGMGL- -----LGQ-- ---------- ---------- --IPPGLFSN ---------- -----LTKLN FLSLR----- ---------- ---------- ---------- ---------- -YNALSGVIP AD-LFTS-LH ---------- ---------- ---------- ---------- -------D-L RNLYLQNN-- ---------- ---------- ---------- ---------- ------LF-- ----SG-PIP DS-------- ---------- ---------- ---------- ---------- -IFSL----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --TNLVRLNL AHNNFSG--- ---------- SIPESF---- ---------- ---------- ---------- ---------- ---------- ---------- -N-------- ---------- ---------- ---------- ---------- ---------- ---------- N--LTSLG-T LYLQGNG-FS GQIP-DL--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------N--- ---------- ---------- ---------- ---------- ---------- ---------- L-PG------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----MVQFNV SNNQ------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -LNGSIP-S- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -------KL- -AGQPKDAFL G--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --TSL--CG- K--------- ---------- --------P- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------L--- ----DSCD-- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- G---SSSSSS IG-------- ---------- ---EG----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -----KK--- ---------- ----KKLSGG AIAGIVIGC- ---------- ----VVGLLL LL--CLLFFC CRKR---G-- -KKE------ ---------- -----TR-SA DVG------- ---------- -----AVSKQ VEVEMPEERG VES------- -----NGGKD GFLGSAIA-A IG-------- ---------- ---------- -----VGGGN KDKGKAE--- ---------- ---------- AVVNDG---- ---------- ---------- ---------- ---------- KS-------L VFFGKMA--- ------KN-F NLDDLLKASA E-------VL GKGTF-GTAY KAAL--ESG- I-TLVVKRLR DVT------- ----V----- --PEKEFREK IEDV----GK M-NHENLVPL RAYYYS---- ----RDEKLL VYDYISMGSL SALLHGNK-- ---------- -------GA- -GRT--PL-- NW--ETRAGI ALGAAHGIAY LHAQGP--S- VSHGNIKSSN ILL----TK- SY-EARVSDF GLAQLVGPSS --T------- ---------- ---------- ---------- --------PN RVAGYRAP-- ---------- ---------- ------EV-T D--------- -PRK---VSQ K-ADVYSFGV LLLEL-LTGK APT------- -HSVLNEE-- -------GVD LPRWV----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --QSVVRE-- ---------- -EWT------ -----AE--- ---VFDLE-L -LRYQNV-E- --------ED ---------M ----VQLLQV AVDCTAQYPD RRP------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---SMAEVT- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -TRVEEL--- ---------- ---------- ---------C RMDSGGGDII DNDA------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -----EVQTA ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC03H1G1255.2 --------MA TGFSST---- --------TA IV--V-FL-- ---------- ---------- -LCFCVSNV- ---------- ---------- --------VL QRTEEDPERQ ---------I LFSFRSS-LE -NPY------ -VL------- --ST-W---- ------T-P- ---------- -----T-I-S -H-------- -------C-- ---------- ---------- ---------- --------K- WDGVF----- ---------- --------C- -----QNGQ- ---------- ---------- ---------- --VVS----- ---------- ---------- -LILSSLSL- -----KGP-- ---------- ---------- --IS-PHIAS ---------- -----LKSLR VLDLS----- ---------- ---------- ---------- ---------- -NNQLSGELP IH-L-SE-LS ---------- ---------- ---------- ---------- -------L-L ETIKLGSN-- ---------- ---------- --CFTGEISP EFGRLTEMKL LDLSGNAL-- ----TG-KIP AQLGQLTKLQ VLALGNNLLS GSLSATLFTK LQSLTSFDVS NNTLSGIIPP EIGGL-R-SL TDLYIG-ENR FSGHL-P--A EIGELS--RL EIFLAPSCL- LE-------- ---------- -----GP--- ---------- ---------- -LPESISK-- ---------- ---------- ---LK-SLKR -FDLSYN-P- -------LK- C-SIPKAI-- GSLEN-LTI- ---------- ---------- -LN------- ---------- ---------- ---------- ---------- -L-AYS---- ---------E INGS--IPSE ---------- ---------- ---LG----- KCRNLMSVML SFNSLSG--- ---------- SLPEELAELP VL-------- ---------- ---------- ---------- ---------- ---------- ---------- ------SFSA ENNQLSGAL- PYWLGRWTQM DALLL----- --SSNRFSGK IP-AEI---G N--CSMLS-H ISLSNNL-LT GPIPKEL--- ---------- ---------- -CNAVALADI ELGNNFLTGT IDDTFVKCGN LSQLGLMD-- ---------- ------NSIA GMI-PEYLSQ LP-LVVLDLD SNNLTGPIPV SLWNSTY--- MLAFSAANNR L------WGT L-PV-EIG-- NAVS------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----LQSLVL SNNQ------ ---------- ---------- ---------- ---------- --IT------ -G-------- ---------- ---------- ---------- ---VI-PKEI GNLTSLSV-- LNLNS----- ---------- ---------N LLEGYIP-D- ---ELGD--- ---------- --------CV S--------- ---------- ---------- ------LTTL -DL------- ------GNNR LR-GSIPETL GHLP------ ---------- ---------- -------QLQ CLVLSHNDLS G-----AIPS KISKYYRQVS IPDSSYVQHH GVYDLSHNKL SGSIPEELGS CVVIVDLLLS NNMLSGEIPR SLAR-LVNLT ------TLDL TGN-LL-TGT I--------- ---------- --------P- ---------- ------KEFG NS-------- ---------- ---------- ---------- ---------- ---------- ---------- -------HKL -QGFYLGN-- --NQL----- -TGSIPESI- ---------- ---------- ---------- ---------- ---------- ---------- ---------G Q--------- ------V--- ---NSLVK-- ---------- ---------- ---------- -------L-N LTGN--MLSG PIPSSFGKL- ---------N GL-THLDLSS NIL-DGEL-- ------PQSL SRMVNLVGLY VQQNRLSGSL DKLFSNSAAW RLEIINLGTN SFTGDLPPS- ---------- ---------- ----LGNLSY LTFLDLHA-- -----NSLTG EIPVELGNLV QLEYLDVSGN S-L-SGKIPE ---TICALPN LD----ILNF T-DNKLKGAI PRNGICQNLS KVSVAGNKDL CGGIVALK-- ---------- C--------- ---------- --------P- ---------- -----ANSFV KRS--LLFNV ---------- -----WGILS VVAGTIIIT- ---------- ----LTIVIV IR--IW---- ---------- -VNR------ ---------- -----SS-RK SDP------- ---------- -----EDSKL ---------D SDDQHL---- 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---------- -SG------- ---------- ---------- LLLGSLWLNG ---------- ----QKLNGG ID--VL---T N--MTFLK-E VWLHSNN-FS GPLPD-F--- ---------- ---------- ---------- ---------- -----SGLKA LETLSLRD-- ---------- ------NAFT GPV-PSS--- ---------- ---------- ---------- ---------- ---------- ------LM-- NLES------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----LKFVNL TNNF------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -FQGPMP-V- ---FKGS--- ---------- ---------- ---------- ---------- ---------- ------VVVD SAK------- ------GTNS FC-------- -SSQ------ ---------- ---------- -------PG- DCDPRVNTLL SIAKAMDYPT NFAK------ ---------- ---NWKGNDP CAD------- ---------- ---------- WFGLTCSNG- ---NITVINF QKM-GL-SGT IS-------- ---------- --------P- ---------- -------EFA SL-------- ---------- ---------- ---------- ---------- ---------- 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---------- -LGDI-F-TL EE-------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -LVLENN-L- -------LE- G-PLPPNL-- GSLNR-LRR- ---------- ---------- -MS------- ---------- ---------- ---------- ---------- -L-SAN---- ---------N LNGT--IPEN ---------- ---------- ---FR----- NLKNMRDFRI DGTSISG--- ---------- TIPGFI---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------G N--WTEMD-R ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---LRISDL- ---------- ------RGEQ MQF-PN---- ---------- ---------- -LHGLTK--- MERLTLRNCS I------FGP I-PR-YVD-- AM-P------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----LKLLDL SNNM------ ---------- ---------- ---------- ---------- --LN------ -D-------- ---------- ---------- ---------- ---TI-PDTF 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---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --RLLAF--- ---------- -QDR------ ----SIE--- ---CFDPF-L ---------- LGKQSN-NED ---------M HTILDSMLQV ALRCILPA-D ERP------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---DMKLVF- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -EQLCSIAQ- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 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---------- ------AGMG TW-------- ---------- ---------- ---------- ---------- ---------- ---------- -------HNL -S-------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- VIPTELGNLR -LTSLNLSSN R-L-SGKIPF ---Q--LENA AF----GKSF S-DNP----- ---------- --------GL CASNPSVEVA S--------- CK-------- ---------- ---------- ---------- ---------- RET--KSDRF ---------- -------PVG LVAALASVA- ---------- ----AVTFLV ----AVLYGP ---------- FVLR------ ---------- -----SH-RK RKQ------- ---------- -----E-SV- ---------- ---------- ---------- -------S-T W--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -K-------Q TSF-HKL--- -------D-F TESDIV---- SNLTENN-II GSGGS-GQVY LVPL--SQSG D-YVAVKRVW RNQRLDRK-- ---------- --HEQQFLAE VQIL----GT I-RHSNIVKL --LCCIF--- ---SEESKLL VYEYMENRSL DIWLHSKNR- ---------- ----LNNAS- RSTPHLVL-- EW--PRRLQI AIGASRGLCY MHHDCSP-P- IIHRDVKSSN ILL----DS- QF-NAKIADF GLARML---- -LKPG---D- --NTVT---- ----A----- ---------- --------VA GSFGYIAP-- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -------G-I -RPS------ -TYL------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 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---------- ------NQIS GRI-PAQIGN CTGLTHIELD NNEITGSIPS EFGNLSN--- LTLLFLWQNR L------EGK I-PS-SIS-- SCHN------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----LEAIDL SQNA------ ---------- ---------- ---------- ---------- --LT------ -G-------- ---------- ---------- ---------- ---SI-PKEI FDLQKLNK-- LLLLS----- ---------- ---------N NLSGPIP-P- ---EIGN--- ---------- --------CS S--------- ---------- ---------- ------LIRL -RA------- ------NDNK LT-GSLPPEI GKLK------ ---------- ---------- -------NLN FLDVGSNHLT G-----IIPP ELSGC----- -------RNL TFLDLHSNSI ---------- ---------- ----SGNLPE NLNQ-LGILQ ------FIDV SDN-LI-EGT L--------- ---------- --------S- ---------- ------PSFG SL-------- ---------- ---------- ---------- ---------- ---------- ---------- -------TSL -TKLVLGK-- --NRF----- -SGPIPTQL- ---------- ---------- ---------- ---------- ---------- ---------- ---------G S--------- ------C--- ---MKLQL-- ---------- ---------- ---------- -------I-D LSGN--QLSG EIPASVGKI- ---------P GLEIALNLSW NQL-SGEI-- ------PA-- ---------- ---------- ---------- ---------- --------E- ---------- ---------- ----FAALDK LGVLDLSH-- -----NQLSG DL-HFLADLQ NLVVLNVSHN N-L-SGHVPD ---TS-FFSK LP----LSVL A-GNP----- ---------- --------DL CFP--GNQ-- ---------- --C------S ADK------- ---------- ---------- ---------- GGG--VR--- ------R--- -----TKAAR VAMVVLLCA- ---------- ----ACALLV AA--LYIILS G--------K IRNR------ ---------- -----KA-HD Y-D------- ---------- -----LD--- --GDNDVELG P--------- ---------- ---------P W--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -E-------V TVY-QKL--- -------D-L SITDVA---- KCLTVGN-VL GRGRS-GVVY KVNI--PSG- L-TIAVKRFR ASDK------ ---------- -HSMSAFSSE IATL----AR I-RHRNIVRL LGWAAN---- ----RKTKLL FYDYLPNGTL GSFLHE---- ---------- -------GF- G-G---LI-- EW--ETRFKI ALGVAEGLAY LHHDCVP-P- ILHRDVKAQN ILL----GD- RY-EPCLADF GLARLM---- -EEE-----N 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MSD------- ---------T SSFSYSSSSV TP-------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------A QLLRLQG--- ---------- ---------- -------SFN CS-------- ---------- ----LTHSSS ---------- ---------- ---------- ---------- -----SVSYS TSNQ------ ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC08H1G2183.2 --------MG VNY------- ---------- ------FLLT ---------- ---------- -FIFALFVLE FS-------- ---------- --------CI EPVCGNAEVR ---------A LMEIKSA--- LDPES----- KKL------- --SS-W---- ---------- ---------- -----TSDGD -R-------- -------CSG ---------- ---------- ---------- --------S- FLGVI----- ---------- --------C- -----NEH-- ---H------ ---------- ---------- K-VTN----- ---------- ---------- -ITLTDKGL- -----TGK-- ---------- ---------- --LS-PAIAE ---------- -----LKCLS GLYLH----- ---------- ---------- ---------- ---------- -YNSLTGEIP KE-L-GD-LT ---------- ---------- ---------- ---------- -------E-L NDLYLNVN-- ---------- ---------- ---------- ---------- ------NL-- ----SG---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --IIPPEL-- GNMTS-LQV- ---------- ---------- -LD------- ---------- ---------- ---------- ---------- -L-SCN---- ---------Q LTGS--IPTE ---------- ---------- ---IG----- FLKKLSVLEL QRNRLTD--- ---------- KIPENL---- ---------- ---------- ---------- ---------- ---------- ---------- -GV------- ---------- ---------- ---------- ---------- ---------- ---------- ---LGTLK-K LYLGFNQ-LS GPIPLNL--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --------AA A-PQ------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----LEVLEV QNNT------ ---------- ---------- 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H--------- ---------- ---------- CSR------- ---------- ---------- ---------- ---------- ---------- ---------- ---SSKFPQA IIVASVITV- ---------- ----TVTLVV AV-------- -------VFG IFRR------ ---------- -----RRLKQ RVG------- ---------- -----NTSDA SDDRLSTDQA KEIYKR---- ------SPSP LLTVEYSN-R WD-------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----PMTPEK SC-------N SMFNEFLN-- -----GFK-F NLEEVESAT- QHFTEIN-LL GRSNF-SAVY KGIL--KDG- S-MVAVKGIS VTSCK----- ---------- -SDETEFMEG LSLL----TS L-KHENLVKL RGFCCS---- --KGRGECFL IYDLASKGNL SQYLDVEV-- ---------- ---------- NSNH--VL-- DW--SKRVSI IKGIAKGLGY LHSTEPDKPS MVHRNISVEK VLL----DQ- QF-TPLILDC GLLKLLADDV ---------- ---------- -VYSA----- -LK------- --------VS AALGYMAP-- ---------- ---------- ------EYI- T--------- -TGR---FTE K-SDVYAFGV IILQV-LSGK GLLDCS---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 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---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------GCGE GK-------L ILFQGGEH-- ---------L TLEDVLNATG Q-------VM EKTSY-GTIY KAKL--ADG- G-TIALRLLR EGSC------ ---------- -KDGGTCLTV IRQL----GR V-RHENLIPL RAFYQG---- ---KRGEKLL IYDYLPNRNL HELLHESR-- ---------- ---------- VGKP--VL-- NW--ARRHKI ALGIARGLAH LHGLETP--- ITHGNVRSKN VLV----DE- FF-VARLTEF GLDKIM---- -------IPA VADEIVS--- ---------- ---------- --------VA KAEGYKAP-- ---------- ---------- ------ELQ- R--------- -MKK---CNS R-SDVYAFGI LLLEI-LLGK KPGKNG---- ----RNGD-- -------IID LPALV----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -KVAVLEET- ---------- ---------- ----TME--- ---VFDMELL -KGIRNP--- -------MEE G--------L ----VQALRL AMGCCAPVAT VRP------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 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---------- ---------- -----NSTSD -P-------- -------CKD ---------- ---------- ---------- --------K- WLGVT----- ---------- --------C- -----NAK-- TL-------- ---------- ---------- S-VEK----- ---------- ---------- -IILDGYDFS -----SGT-- ---------- ---------- --FDVTTICN VEPI------ -----AHTLF FLSLK----- ---------- ---------- ---------- ---------- -NGLLQGKNF DS-I-DK-CK ---------- ---------- ---------- ---------- -------H-L RHLVLGGN-- ---------- ---------- ---------- ---------- ------RF-- ----SG---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --------S- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------IPQS ---------- ---------- ---FS----- RLNNLKRLDI SNNRLSG--- ---------- VLPDLS---- -------R-- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---ISGLI-E FEAQNNQ-LS GEIPE----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------F DFSN------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----FVAFNV SFNN------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -FSGSIP--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --------P- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --------EG D--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --------S- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --F------- ---------- -----PVSRY M-ENS----- ---------- --------LL CGSPLARK-- ---------- CSSL-----S EDSESADH-- ------DKPK R--------- ---------- SLS-RDE--- ---------- --------IL MFSGYFLIG- ---------- ----LALVLL IL--LCVYRK RK-------Q KQQK------ ---------- -----KK-ES RIELMKKVAT VDHDSTT--- -TSMDQSKKG ASNSDISSA- ---------- ---------- VISSDDSN-- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------TAVS QS-------L VVLTSPE--- -----ANNGL RFEDLLKAPA E-------LL GRGKH-GSMY KVMC--DNP- KMTLAVKRIK DWS------- ---------- -ITGSEFKKR MQKL----DK I-RHPNVLPA VAFYSS---- ----RQEKLL VYEYQDNGSL LLLLQGIQ-- ---------- ---------- TGQ---RF-- HW--SSRLSI AAGIADALAF MHQELQHDR- IAHGNLKSSN IFL----TN- NM-EPMIGEY GLMSIAEIST -------TTA SNSHYVFPIT DENVG----- ---------- -------AI- ----F----- ---------- ---------- ---------- ---------- ---------- K-EDVYAFGV ILLEL-LTGK --VQNN---- ---------- -------GIE LASWV----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --VSVLRE-- ---------- ---------- --EWTVE--- ---VFDRT-L -IQEGAS--- --------EE R--------M ----VNLLQV AVKCVNQSHE ARP------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---SINQVA- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -LMVTTIRD- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -EDD------ ---------- ---------- ---------- ---------- --RSIDVSES TSTII----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC09H1G2747.2 --------MS SSSSN----- ------PNKK YHFFL-F--- ---------- -------LVT -LFFT-S--- ---------- ---------- ---------- SSSAV----- ---------- ------T-T- DVVAP----- --F------- --SN-W---- ------D-I- ---------- -----LDD-T -P-------- -------C-- ---------- ---------- ---------- --------K- CSFIK----- ---------- --------C- -----NF--- QG-------- ---------- ---------- F-ITE----- ---------- ---------- -INIQSIHL- -----ELP-- ---------- ---------- --LP-TNLSS ---------- 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---------- ---------- ---------- --------E- ---------- ---------- ----ISSLSK LSILDLSH-- -----NKLEG NL-NPLARLD NLVSLNVSYN N-F-TGYLPD ---NK-LFRQ LP----SSDL D-GNE----- ---------- --------GL CSF--GRPS- ---------- CFL------S NID------- ---------- ---------- ---------- GVG--VAKNG N--DEGR--- -----SKKLK LAIALLVIM- ---------- ----TIAMVI MG--TIAI-- ---------- IRAR------ ---------- -----RA-MR R-D------- ---------- -----DDSEM --GDSWA--- ---------- ---------- ---------- W--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -Q-------F TPF-QKL--- -------N-F SVDEIL---- RCLVDTN-VI GKGCS-GMVY RADM--NNG- D-VIAVKKLW PITMTTTNGG NDEKC----- -GVRDSFSAE VKTL----GS I-RHKNIVRF LGCCWN---- ----RSTRLL MYDYMPNGSL GSLLHE---- ---------- -------RS- G-N---PL-- EW--ELRYQI LLGAAQGLAY LHHDCAP-P- IVHRDIKANN ILI----GL- EF-EPYIADF GLAKLV---- -DDG-----D FGRSSN---- ----T----- ---------- --------VA GSYGYIAP-- ---------- ---------- ------EYG- Y--------- 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---------- ---------- ---------- ---------- ---QPNR--- ---------- ---------- -------KFA LG-------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC09H1G0587.2 --------MG TGV------- ---------- ------FIFF ---------- ---------- -VWFAVFL-- ---------- ---------- --------LI NGSQA---QP ---------G FVSLDCG--- GKDNFTD--E LGLK------ -----WTP-- ------D-TQ MI-SGNIANI SV---ANETR -TQYMALRYF PADNRKYCYT LDVIP--RNR YLVRATFLYG NFD-KDNVYP KFDISLGTTH WATIVISDAN TMEYQEVIFL AKEPSVSVC- ---LSNAT-- TG-------- ---------- LPF------- --IST----- ---------- ---------- -LELRHFNG- ---------- ---------- ---------- -SIYMTEFEN --DF------ ----FMSVSA RINFGAASDD PVRYPDDPFD RIWASDTIKK ANYLVDVASG TERVSTKMPI DVNTLNGEMP PQKA------ ---------- ---------- ---------- ---------- ---------M QTAVVGRNGS LTY------- ---------- ---------- ---------- ------RL-- ----NLDGFP GF-------- ---------- ----GWA--- ---------- ---------- -FTYF-A-EI EDLKPGDSRK FRLVL-PGAP DISKLA---- --VNIQENA- ---------- ---------- ----HGK--- ---------- YRLYE----- --PGYF---- ---------- ---------- ------NLSL PFVLS----- -------FRF G-KTSDST-M GPLLNAMEV- -NRYVK---- -RTDGSLDGP VIS------- ----S----- ---------- ---------- ------LVSH YS-SANL--- --------IN EGGDPCLPVP ---------- ---------- WSWIRCDSDI R-PRITSIKL SGKNLTG--- ---------- NIPSEL---- ---------- ---------- ---------- ---------- ---------- ---------- -TK------- ---------- ---------- ---------- ---------- ---------- ---------- ---LSGLV-E LLLDGNS-LT GSIP-DFS-- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -----GCP-- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---NLQIIHL ENNQ------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -LSGQLP-S- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -TLE------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----DL---- ---------- ---------- --------S- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -----NL--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---KELYVQN NML-TGSV-- ------PS-- ---------- ---------- ---------- ---------- --------G- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --LRDNGVIL ---NY----- ---T------ --GNF----- ---------- --------NL HEGE--TS-- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 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---------- ------KDPR QRS------- ---------- ---------- ---------- ---------- ---------- ---------- -------TAL CG-------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- GT----PP-- ---------- ---------- ---------- ---------- ---AKSNPAQ ---------- ---------- ---------- ---------- ---------- ---------- -------SNN K-HR------ ---------- ---------- ---------- ---------- ---------- ---------- ---------T VEG------- ---------- ------RAKH ---------- ---------- ----KSASKP TW-LF----- ---------- -VLEVVTGVI ---------- ----AGSLFL VA--ILAAIQ KC-------- ---------- ---------- -----KN-ES SII------- ---------- ---------- ---------- -------I-- ---------- ---------P WK-------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------KSAS MKDHMKDHMA VYVDTEMLKD -----VER-Y SRQELEVAC- EDFSN---II GSSPD-SLVY KGTV--KGG- P-ELAVISIC VKE-EQ---- --------WT TYLELYFQKE VAEL----AR I-NHENTAKL LGYCRE---- --SSPFTRML VFEYASNGTL YEHLHYGEGC ---------- ---------- ------QL-- SW--TRRMKI VIGIAKGLKY LHSELDP-P- FTISELNSNA VYL----TE- DF-SPKLVDF ESWKTTFARS --------EK NSGAISS--- ---------- ---------- ---------- ---------- ---------- ---------- ------EGA- -----MCVLP NSLQSRHLDM Q-GNIYAFGV LLLEI-ISGR PPNCKD---- ---------- -------KGC LVDWA----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --KEFLEL-- ---------- PEV------- ----LPY--- ---VVDPE-L -KHFR----- -------YED ---------L ----KVISEV VNLCIHPSSS SRT------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---SMRDLC- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -AMLESDID- -----T---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -SITAEL-KA SSLAW----- ---------- -----AELAL SS-------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC07H1G2062.2 --------MA SYSNS----- -----AIQQH LFFVL-LIL- ---------- -------LFF -TGF------ ---------- ---------- ---------- -AESLNEEGL ---------I LLEFKES-L- NDPDN----- -NL------- --ES-W---- ------N-S- ---------- -----SNL-N -P-------- -------C-- ---------- ---------- ---------- --------K- WDGVK----- ---------- --------C- -----SK--- ND-------- ---------- ---------- Q-VIS----- ---------- ---------- -LNIDNRNL- -----SGS-- ---------- ---------- --FS-SRICE ---------- -----LPYLT VLNVS----- ---------- ---------- ---------- ---------- -SNFISGQIP DD-F-AS-CH ---------- ---------- ---------- ---------- -------S-L EKLNLCTN-- ---------- ---------- ---------- ---------- ------RF-- ----HG-EFP LQLCNITSLR QLYLCENYIS GE-------- ---------- -------IPQ DIGNL-S-LL EELVVY-SNN LTGRI-P--V SIGKLK--KL RIIRAGRNY- LS-------- ---------- -----GP--- ---------- ---------- -IPAEVSE-- ---------- ---------- ---CD-SLQV -LGVAEN-R- -------LE- G-SFPVEL-- QRLKN-LIN- ---------- ---------- -LI------- ---------- ---------- ---------- ---------- -L-WAN---- ---------S FSGA--IPPE ---------- ---------- ---VG----- NFSKLELLAL HENSFSG--- ---------- QIPKEI---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----GKLTNL RRLYI----- --YTNQLNGT IP-WQM---G N--CLSAV-E IDLSENQ-LG GSIPKSL--- ---------- ---------- ---------- ---------- -----GQLSN LRLLHLFE-- ---------- ------NRLH GKI-PKELGV LKLLKNFDLS INNLTGRIPA VFQNLAF--- LENLQLFDNH L------EGP I-PR-FIG-- LKSN------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----LTVVDL SKNN------ ---------- ---------- ---------- ---------- --LE------ -G-------- ---------- ---------- ---------- ---RI-PSNL CQFQKLTF-- LSLGS----- ---------- ---------N KLSGNIP-Y- ---GLKT--- ---------- --------CK S--------- ---------- ---------- ------LEQL -ML------- ------GDNL LT-GSFSFDL SKLE------ ---------- ---------- -------NLS ALELFHNRFS G-----LLPP EVGNL----- -------RRL ERLLLSNNNF FGKIPPDIGK LVKLVAFNVS SNRLSGDIPH ELGN-CLSLQ ------RLDL SKN-SF-TGN L--------- ---------- --------P- ---------- ------DELG RL-------- ---------- ---------- ---------- ---------- ---------- ---------- -------VNL -ELLKLSD-- --NKF----- -NGQIPGGL- ---------- ---------- ---------- ---------- ---------- ---------- ---------G G--------- ------L--- ---ARLTD-- ---------- ---------- ---------- -------L-E MGGN--FFSG SIPIELGYL- ---------G TLQISLNLSH NAL-NGSI-- ------PS-- ---------- ---------- ---------- ---------- --------A- ---------- ---------- ----LGNLQM LETLYLND-- -----NQLFG EIPTSIGQLM SLIVCNLSNN N-L-VGSVPN ---TP-AFKR MD----SSNF A-GNV----- ---------- --------GL ---SVGL--- ---------- CTS------N SIH--CDPPP AP---WIAP- ---------- -----KSNWL KHG--SS--- ------R--- -----QKIIT AVSATVGMI- ---------- ----SLVLIL VI--CRII-- ---------- ---------- ---------- -----RG-HK A-A------- ---------- -----FVSV- --ENQVKPDD LNDHYF---- ---------- ---------P R--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -K-------G FTY-QDL--- ---------- --VDAT---- GNFSDSA-II GRGAC-GTVY RAHM--ADG- E-FVAVKKLK PQGETA---- ---------- -SVDSSFQAE LSTL----GK I-NHRNIVKL YGFCYH---- 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---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------V CTSPPSPSSE TPLS------ ---------- ---------- -EADA----- ---------- ---------- ---------- ---------- ---------- ---------N K--DCKN--- ---------- ---------- -------LFN VN-------- ---------- ---------- ---------- ---------- ---------- ---------- ------VS-- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC03H1G1507.2 --------M- ---------- -----FLFDL VHCFI-FFA- ---------- -------SIV -AVFSESLP- ---------- ---------- --------Q- -------DSV ---------H LLGFRSN-L- PEPS------ QQL------- --LP-W---- ------N--- ---------- -----Q-SVS -H-------- -------C-- ---------- ---------- ---------- --------K- WKGVT----- ---------- --------C- -----YSV-- KTSQVKSLYF RDFLLSGILD KAFPNLCHLP R-LVS----- ---------- ---------- -LDLSGNHL- -----TGG-- ---------- ---------- --IP-AMLAN ---------- -----CSQLD TIFLN----- ---------- ---------- ---------- ---------- -DNRFSGSIP PE-I-FK-SK ---------- ---------- ---------- ---------- -------R-L VYLELGYN-- ---------- ---------- ---------- ---------- ------QL-- ----NG-TIP SE-------- ---------- ---------- ---------- ---------- -VGLS-T-SL QYLGLW-NNL LSGNI-P--K ELFGLP--NL TDLYIHTNN- LTGPLPDFLS SCSLSLLAIH QNRFSGS--- ---------- ---------- -LPISLGNCH NLSAFYATSA HLGGVISPEV FRGLS-NLEL -LYLDDN-N- -------FE- G-EIPETLWN GKLRE-LVLS INNFNGS-IS EKIGGCHQMT YID------- ---------- ---------- ---------- ---------- -L-SAN---- ---------K LSGQ--IPKS ---------- ---------- ---VG----- RLKNLNKLLL YDNMFSG--- ---------- SLPAEV---- ---------- ---------- ---------- ---------- ---------- ---------- -G-------- ---------- ---------- -----NCTSL AEISL----- --VSNFISGE IP-SEI---C S--LQNLE-T FNAFSNK-IQ GQIPECI--- ---------- ---------- ---------- ---------- -----GRISG LQELALYE-- ---------- ------NRLT G--------- ---------- ------KLPL GITNMTK--- LSFLSLAHNN L------TGE V-PP-DLGKD NFPGL----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----VKV-DL GYNN------ ---------- ---------- ---------- ---------- --FS------ -G-------- ---------- ---------- ---------- ---QI-PSKL CNGNRLAV-- LALENNRFNG SFPTYLANCK SLYRVKLPNN NLQGSIP-D- ---DIEK--- ---------- --------NE N--------- ---------- ---------- ------ISYL -DV------- ------RQNM LV-GRIPAAF GYWT------ ---------- ---------- -------NLS MIDLSENMFN G-----SIPT ELGK------ ---------- ---------- ---------- ---------- ---------- -----LQNLV ------KLSI SSN-RL-TGQ I--------- ---------- --------P- ---------- ------FQLS NS-------- ---------- ---------- ---------- ---------- ---------- ---------- -------EKL -EELDLSN-- --NSL----- -SGRIPKEI- ---------- ---------- ---------- ---------- ---------- ---------- ---------A SSSV------ ------L--- ---TNLLL-- ---------- ---------- ---------- -------Q-D ---N--KLSG ALPDTFSSS- ---------Q ML-VKLQLGN NLL-EGPI-- ------PC-- ---------- ---------- ---------- ---------- --------SL SKLMQPGFSL NLSMNKFTGE IPRCLGNLEK LEVLDISS-- -----NNLSG AIPSEMEKMS SLSFLNISFN S-L-SGKVPN T-WEK-LLSS RP----GSAL --GNP----- ---------- --------GL C--LIDTEGS N--------- CKH------V KKS------- ---------- ---------- ---------- ---------- ------Q--- ---VKWKTLA GVISGCVLS- ---------- ----MAIIVA AM--YLLVTR IW-------- HPSL------ ---------- -----LN-KH RLV------- ---------- -----KCQS- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -G-------I EDLP------ ------DG-I TFEDIVHAT- EGWSENY-VI GRGTH-GTVY KMESA-KSN- K-LWAVKKVD LAQR------ ---------- -----AFNDE MRSL----NS V-RHRNLVRL GGYCMK---- --HGYGF--I LTEFIPGGTL HDVLHQR--- ---------- ---------- KPPV--VL-- DW--KSRHRI ALGIAQGLSY LHHDSVP-Q- IIHRDLKSDN VML----DS- EM-VPKIGDF GIAKMVSD-- ---------- -EENSTN-S- ----N----- ---------- --------IV GTLGYIAP-- ---------- ---------- ------ENA- Y--------- -SVQ---LTE K-SDVYSYGI LLLEL-FCRK MPVDPS-FE- -------E-- -------GLD IVFWV----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --RKNLQ--- ----RS-NN- ---------- ----FLS--- ---FLDEE-I -RLWNVEE-- -QWKAL--KL ---------V ----DLALQ- ---CAQLEAS TRP------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---AMRDVV- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------R YD-------- ---------- ---------- ---------- ---IPGL--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --------Y- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC09H1G3008.2 --------MT NKASTW---- --------EA CVLMI-IL-- ---------- ---------- -LCFTQQPV- ---------- ---------- --------VT TGYLVN-DME ---------L LKALRNS-LV LKRD------ -VI------- --PS-W---- ------F-D- ---------- -----TKT-T -P-------- -------C-- ---------- ---------- ---------- --------N- WTGIK----- ---------- --------C- -----EGER- ---------- ---------- ---------- --VIQIDFPC TGSPLNVPFP GNIGKFRSLK HLNLSHCAL- -----TGT-- ---------- ---------- --IP-ADVWS ---------- -----LENME TLDLT----- ---------- ---------- ---------- ---------- -DNRLTGELP PT-I-SK-LR ---------- ---------- ---------- ---------- -------N-L RYLVLDNN-- ---------- ---------- --GFSGSLPS TICELKELRE LSVHANSF-- ----TG-NLP GEIGNMEKLQ SLDFSSNFFS GNLPSSL-GN LMELLFVDAS QNNLTGLIFP EIGKL-G-ML RILSLS-SNM LSGPI-P--A TIGHLK--QL QVLDLQNCK- FT-------- ---------- -----GS--- ---------- ---------- -IPEEISE-- ---------- ---------- ---LS-NLNY -LNVAQN-E- -------FD- G-ELPSSI-- GKLEN-LLY- ---------- ---------- -LI------- ---------- ---------- ---------- ---------- -A-SNA---- ---------G LSGT--IPSE ---------- ---------- ---LG----- NCKRLKSINL SFNSFSG--- ---------- VLPDELSGLD SLK------- ---------- ---------- ---------- ---------- ---------- ---------- ------SLVL DSNRLSGPL- PMWISNWTQV ESIMV----- --SKNFLSGP LP-PLY---- ---LPLLS-V LDVSANS-LS GELSSEI--- ---------- ---------- -CGAKSLNVL VLSDNNFTGD IQSTFTNCSS LTDLVLSG-- ---------- ------NNLS GKL-PSYLGE LQ-LITLELS KNQFSGMVPY QLWESKT--- LMGISLGNNM L------EGP I-PA-TIA-- KLST------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----LQRLQL DNNQ------ ---------- ---------- ---------- ---------- --FE------ -G-------- ---------- ---------- ---------- ---SI-PRTI GNLKNLTN-- LSLHG----- ---------- ---------N KLTGGIP-L- ---ELFE--- ---------- --------CT K--------- ---------- ---------- ------LVSL -DL------- ------GANS LS-GEIPRSI AKLK------ ---------- ---------- -------LLD NLVLSNNQFS G-----PIPE EICSGFQNMP LPDSEFTQHY GMLDLSNNEL AGSIPHSIKD CIVVTELLLQ GNKLTGSIPP EISQ-LGNLT ------MLDL SFN-SL-TGP VF-------- ---------- --------P- ---------- ------QLFP MS-------- ---------- ---------- ---------- ---------- ---------- ---------- --------SL -QGLILSH-- --NQI----- -SGSIPDNLD ---------- ---------- ---------- ---------- ---------- ---------- ---------S M--------- ------M--- ---PSLVK-- ---------- ---------- ---------- -------L-D LSSN--WLSG SLPPSAFRL- ---------K SL-TYLDISM NSF-SGSL-- ------SFNV GISSSLLVLN ASNNQLSGAL DD-------- ---------- --------S- ---------- ---------- ----LSNLTS LSKLDLHN-- -----NSITD NLPPSLSALA SLIYLDLSSN S-F-QKSFPC ---SICDIQG LV----FSNF S-GNKFIDLA P--------- --------DV C--TKARK-- ---------- CIP------S EPV------- ------LPP- ---------- -----RENYP SAP--VLSHA ---------- ------SVLG IALGASILS- ---------- ----LVVLIV VL--RWRMLR QE-A-----V LVDRGK---- ---------- ---GKQG-KK TDP------- ---------- -----T---- ---------- STDELL---- ---------- -I----KK-P KE-------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -------HLS IN-------I ATFEQSL--- ------LR-I NPTAILSAT- ENFSKSY-II GDGGF-GTVY KAKL--PEG- Q-IIAVKRLN GGHM------ ---------- -HGDREFFAE METI----GK V-KHENLVPL LGYCVF---- ----ADERFL IYEYMENGSL DFWLRN---- ---------- -------QA- DAVE--AL-- DW--PTRFKI CLGSAVGLSF LHHGFVP-H- IIHRDIKSSN ILL----DK- NF-EPRVSDF GLARIIS--- ---------A CESHVST--- ----I----- ---------- --------LA GTFGYIPP-- ---------- ---------- ------EYG- Q--------- -TMT---ATT K-GDIYSFGV VMLEL-ATGR APTGQ---AD ------VE-- -------GGN LVGWV----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --RWMVS--- ---------- -NGR------ ----EIE--- ---TLDPF-I -SGS------ -GLLK---DQ ---------M ----LRVLAI ARLCTSDEPW KRP------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---SMLEVV- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -KLLKEA--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---KNNG--- ---------- ---------- -------ACG V--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC08H1G2337.2 ---------- -----MRLC- ---------- ------VVFQ ---------- ---------- -VLVTVGL-- ---------- ---------- ------VLGI CDAFPSNEVY ---------A LNTFKEA-IY EDPL------ LVL------- --SN-W---- ------N--- ---------- -----GLDSD -P-------- -------C-- ---------- ---------- ---------- --------G- WAGVF----- ---------- --------CS -----MAQD- ---------- ---------- ---------- H-VIK----- ---------- ---------- -INISGASL- -----KGF-- ---------- ---------- --LS-PNLHL ---------- -----LSSLQ ELILH----- ---------- ---------- ---------- ---------- -GNVLIGTIP KE-I-GL-LK ---------- ---------- ---------- ---------- -------N-L KALDLGAN-- ---------- ---------- ---------- ---------- ------QL-- ----TG---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------P--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------IPSE ---------- ---------- ---LG----- NLTNIMKINL QSNGLTG--- ---------- KLPAEL---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------G N--LKYLE-E LRLDRNK-LQ GLVPANTG-- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------SDFT SGV------- ---------- ---------- -RGMYASG-- ASATGFC--R T--------- ---------- --SQ------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----LKVADF SFNF------ ---------- ---------- ---------- ---------- -LIG------ ---------- ---------- ---------- ---------- ---SI-PK-- ---------- ---------- ---------- ---------- -CLGYLPKS- ---SF----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------QGNC LQ-------- --------H- ---------- ---------- ---------- ---------- ------KDPK QRS------- ---------- ---------- ---------- ---------- ---------- ---------- -------AAL CG-------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ST----PP-- ---------- ---------- ---------- ---------- ---PTSHAST ---------- ---------- ---------- ---------- ---------- ---------- -------LSN K-HQ------ ---------- ---------- ---------- ---------- ---------- ---------- ---------P VE-------- ---------- ------EPRH ---------- ---------- ----QTSSKP TW-LL----- ---------- -ALEVVTGVM ---------- ----VGSLFI VG--LVTGLQ RL-------- ---------- ---------- -----KN-KS S-I------- ---------- ---------- ---------- -------I-- ---------- ---------P WK-------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------KSGS ----EKDHMT IYVDTGMLKD -----VVR-Y SRQELEVAC- EDFSN---II GSSPD-SIVY KGTM--KGG- P-EIAVISLC VKE-EH---- --------WT AYLELYFQKE VAEL----AR I-NHENAGKL LGYCRE---- --SSPFTRML VFEYASNGTL YEHLHYGEGC ---------- ---------- ------QL-- SW--TRRMKI VIGIAKGLTY FHSELDP-P- FTISELNSNS VYL----TE- DF-SPKLVDF ESWKSIISRS --------EK NSGVISS--- ---------- ---------- ---------- ---------- ---------- ---------- ------EGA- -----ICVLP NTLESRHLDV Q-GNIYAFGV LLLEI-ISGR PPYCKD---- ---------- -------KGC LVDWA----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --KEFLEM-- ---------- PEV------- ----LSY--- ---VVDPE-L -KHFK----- -------QED ---------L ----KVICEV INLCIHPTTS RRT------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---SMKDLC- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -AILESNID- -----T---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -SITAEL-KA SSLAW----- ---------- -----AELAL SS-------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC08H1G1788.2 --------MG GFSLKI---- ---QDLLFLS VLLLC-IF-- ---------- ---------- ---------- ---------- ---------- --------PR LTLALNPDGQ ---------A LVNFRIL-I- SGSD------ GVL------- --EQ-W---- ------R--- ---------- -----PEDSD -P-------- -------C-- ---------- ---------- ---------- --------G- WKGVQ----- ---------- --------C- -----DPK-- SK-------- ---------- ---------- R-VTS----- ---------- ---------- -LSLPNHKL- -----SGY-- ---------- ---------- --IS------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------P--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----D----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---IG----- KLDQLQFLAL HDNNFYG--- ---------- AIPPAL---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -G-------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------N ---------- ---------- ---------- --------C- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -------TKL ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---KSLFLQS NYL-SGWI-- ------PD-- ---------- ---------- ---------- ---------- --------E- ---------- ---------- ----LGNLPE LENLDLSS-- -----NSLSG NIPPSLGKLN NLGIFNVSTN F-L-VGQIPS ---DG-HLAK FG----NDSF L-GNR----- ---------- --------NL CGKQVSQD-- ---------- CNT------- -GGSS----- ------ISPS ---------- ---------- PDS--AQSQN ---KNGR--- ---------- --LLISASA- ---------- ----TVGALL LV--ALMCFW GCFL------ ---------- ---------- ---YKRL-GK NDG------- ---------- -----RSLAM D--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------ICAG AS-------I VMFHGDL--- -------P-Y SSKDIIKKL- ETLNEEH-II GSGGF-GTVY KLAM--DDG- N-VFAVKRII KMNE------ ---------- -GFDRFFERE LEIL----GS I-KHRYLVNL RGYCNS---- ----PTSKLL IYDFLSGGSL DEVLHERSE- ---------- ----Q----- -------L-- DW--GARLTV IMGAAKGLAY LHHDCSP-R- VIHRDIKSSN ILL----DG- NF-EARVSDF GLAKLL---- --------GD EESHITT--- ----I----- ---------- --------VA GTFGYLAP-- ---------- ---------- ------EYM- Q--------- -SGR---ATE K-TDVYSFGV LVLEV-ISGK RPTDAS-YIE -------K-- -------GFN IVGWL----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --NYLAS--- ---------- -ENR------ ----RTE--- ---IVDPL-C -ERVQT---- --------ES ---------L ----DSLLSV ATQCVSSSPD DRP------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---TMHRVV- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -QILESE--- -----V---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------M TPCPS----- ---------- -------DFY DSS-S----- ---------- ---------- ---------- ------D--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC09H1G1916.2 --------MN ---------- --------LL TIFIL-FLF- ---------- -------YYY -SVFANG--- ---------- ---------- --------VV AKVDLNDEVS ---------I LLSIKES-L- VDPL--D--- -HL------- --RD-W---- ------TVPN ---NATAGNN ----RSII-V -P-------- -------C-- ---------- ---------- ---------- --------S- WTGVE----- ---------- --------C- -----NS--- HG-------- ---------- ---------- A-VEK----- ---------- ---------- -LNLSHMNL- -----TGT-- ---------- ---------- --VS-NDIQK ---------- -----LKSLT SLNLC----- ---------- ---------- ---------- ---------- -CNEFSSPLP KS-F-SN-LT ---------- ---------- ---------- ---------- -------A-L RSIDVSQN-- ---------- ---------- ---------- ---------- ------YF-- ----VY-DFP -VG------- ---------- ---------- ---------- ---------- -LGMS-E-AL MYLNAS-SNN FSGYL-P--E DIGNAT--LL ETLDFRGNF- FE-------- ---------- -----GS--- ---------- ---------- -IPKSYKN-- ---------- ---------- ---LG-KLKF -LGLSGN-N- -------LT- G-HIPGEL-- GQLSS-LET- ---------- ---------- -VV------- ---------- ---------- ---------- ---------- -LGY-N---- ---------L FEGG--IPAE ---------- ---------- ---FG----- NLTNLKYLDL AIGNLGG--- ---------- SIPSEL---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----GKLKLL DTIFL----- --YKNKLEGK IP-PEI---G N--MTSLQ-L LDLSDNM-LT GEIPAEI--- ---------- ---------- ---------- ---------- -----AELKN LQLLNIMS-- ---------- ------NKLS GSV-PPGI-- ---------- ---------- --GGLTQ--- LEVVELWNNS L------SGP L-PS-DLG-- RNSP------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----MQWVDI SSNS------ ---------- ---------- ---------- ---------- --FT------ -G-------- ---------- ---------- ---------- ---PI-PAGL CAKGNLTK-- LIMFN----- ---------- ---------N AFSGPIP-T- ---GLST--- ---------- --------CT S--------- ---------- ---------- ------LVRV -RM------- ------QNNL LS-GTIPAGF GKLG------ ---------- ---------- -------KLQ RLELANNSLT G-----QIPS ---------- ---------- ---------- ---------- ---------- ---------- DLAS-STSLS ------FIDF SRN-HI-QSS I--------- ---------- --------P- ---------- ------SFIL AI-------- ---------- ---------- ---------- ---------- ---------- ---------- -------PTL -QNFIASD-- --NKM----- -IGEIPDQF- ---------- ---------- ---------- ---------- ---------- ---------- ---------Q D--------- ------C--- ---PSLTV-- ---------- ---------- ---------- -------L-D LSTN--HFTG DLPASIASC- ---------E KL-VTLNLRN NQL-NGPI-- ------PR-- ---------- ---------- ---------- ---------- --------A- ---------- ---------- ----ISMMPT LAILDLSN-- -----NSLTG GIPENFGNSP ALEMLNVSHN K-L-EGPVPE ---NG-MLRT IN----PDDL I-GNA----- ---------- --------GL CGGVL-PP-- ---------- CSH------N ---------- ---------- ---------- ---------- A-A--YTSKE ------K--- -----SLHAK HIIT-GWLT- ---------- ----GVAALL LF--VTAG-- ---------- LVAR------ ---------- -----SL-YK RWH------- ---------- -----ENGSC F--------- --EPSF---- ---------- -EMSRGEW-P W--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -R-------L MAF-QRL--- -------G-F TSNDIL---- ACLKESN-VI GMGAT-GVVY KAEM--QRE- NMVVAVKKLW KSGTDIEMG- ---------- -H-SDDLVGE VNVL----GK L-RHRNIVRL LGFLHN---- ----KRDAMI IYEYMQNGSL GEVLHG---- ---------- -------KQ- AAG---RLLV DW--VTRYNI ALGVAQGLAY LHHYCHP-P- VIHRDVKSNN ILL----DA- NL-EARIADF GLARTM---- -LK------- KNETVS---- ----M----- ---------- --------VA GSYGYIAP-- ---------- ---------- ------EYG- Y--------- -TLK---VDE K-SDIYSYGV VLMEL-LTGK RPLDPE-FG- -------E-- -------SVD IVEWF----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --RMKIR--- -----DNKS- ---------- ----LEE--- ---ALDPN-V --GA------ -TQHVQ--EE ---------M ----LLVLRI AILCIAKLPK DRP------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---SMRDVL- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -TMLDEA--- ---------- ---------- ---------- --------KP R--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---RKS-SSN SGGS------ ---------- ---------- -DAAT----- ---------- ---------- ---------- ---------- ---------- ---------- ------T--- ---------- ---------- -------NKD KP-------- ---------- ---IFSTSPV ---------- ---------- ---------- ---------- ---------- NGLL------ ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC03H1G2333.2 MKERRRTCVG GME------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --------VL RGAKAQVDQS ---------G FVSIDCG-IP QGSNYTDV-A TGLQ------ -----YVS-- ------D-SG FIDTGSNATI SSEFHSDGLE -QQLYTLTSF P-EGKRNCYT IRVPEGKGKK YLIRASFLYG NYDRKSQLVI NFDLHLGVDF WTTIQIVNAS VPLYGEIIHI LSSDFVQVC- ---LVNKD-- RG-------- ---------- TPF------- --ISA----- ---------- ---------- -LELRLLNT- ---------- ---------- ---------- -TIYKTTSGS ---------- -----LQTFV RLDLGSTATQ LVRYQDDIYD RLW------- --WPYNNVAN TISLSTTSTI D-NTNS-YLP PSKV------ ---------- ---------- ---------- ---------- ---------L STAITADNDT DGI------- ---------- ---------- ---------- ------SLWW EPANSTDEY- ---------- ---------- -----YI--- ---------- ---------- -YLHF-A-EI EANHVN--RQ FNIYF-DG-- ---------- ---------- ---------- ---------- ---------- ---------- -ELYDGAL-- -APDYM---- 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---------- ---------- ---------- ---------- ---------- ---------- ---------- -T-------L MSF-HKL--- -------G-F NEYEIL---- DALEEDN-LI GSGSS-GKVY KVVL--SKG- D-TVAVKKI- LRSVKIVDDC SD----IEKG SIQEDGFEAE VETL----GK I-RHKNIVKL --WCCCT--- ---TRDCKLL VYEYMPNGSL GDLLH----- ---------- -------SS- KSG---LL-- DW--PMRYKI AMDAAEGLSY LHHDCAP-P- IVHRDVKSNN ILL----DG- EF-GARVADF GVAKAV---- -DANA---KA -IKSMS---- ----V----- ---------- --------IA GSCGYIAP-- ---------- ---------- ------EYA- Y--------- -TLR---VNE K-SDIYSFGV VILEL-VTGK RPVDPE-FG- -------E-- --------KD LVKWV----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --CSTLD--- ----QKGVD- ---------- ------H--- ---VIDPK-L -D-T------ -CFKE----E ---------I ----CKALNI GLLCTSPLPI NRP------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---SMRRLV- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -KMLQEVG-- ---------- -GGN------ ---------L PKAASKD--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------G K--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------L TPY------- ---------- ---------- -YYEE----- ---------- ---------- ---------- ---------- ---------- ---------- --ASDQG--- ---------- ---------- -------SVA ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC01H1G3822.2 --------MM KSESDMGFGY L-VKVLDFYQ ETFFL-LACS YCWLEESGVK VKDNLLDIRK ALFTRLALKY SFSFPTKGWG FGCSRKRFCY ----AGNGFK KSCLPPDFST ---------A LFSLKSS-W- N--------- NLP------- --PN-W---- ------E--- ---------- -----GS--D -P-------- -------CGS ---------- ---------- ---------- --------S- WAGIV----- ---------- --------C- -----D-N-- SR-------- ---------- ---------- --VTS----- ---------- ---------- -IKLSGMGL- -----EGN-- ---------- ---------- --QF-GDLSS ---------- -----LTALQ ILDLS----- ---------- ---------- ---------- ---------- NNVGLKGTLP P--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -------SIG ---------- ---------- ---------- ---------- ---------- ---NL----- ---------- ------K--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------NLTT -LILVGC-S- -------FF- G-PIPESI-- GSLQQ-LVF- ---------- ---------- -IS------- ---------- ---------- ---------- ---------- -L-TSN---- ---------S FTGP--IPPS ---------- ---------- ---IG----- NLSKLSWLDL SDNKING--- ---------- TIPISQ---- ---------- ---------- ---------- ---------- ---------- ---------- -GS------- ---------- ---------- TLGLDSLVNT RHLHL----- --SKNQLSGL IQPQLF---N A--SMKLI-H VILDHNQ-LT GEIPESL--- ---------- ---------- ---------- ---------- -----GSLQN LEILRLDW-- ---------- ------NSLN GSV-PSKL-- ---------- ---------- --SNITS--- LSELYLSNNN L------NGS I-P--DLA-- KMQL------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----LTYVGM SNNS------ ---------- ---------- ---------- ---------- --FNA----- -S-------- ---------- ---------- ---------- ---DV-PAWF RKLPLLKT-- IYMEN----- ---------- ---------T TLQGQIP-A- DLFRFPN--- ---------- ---------- ---------- ---------- ---------- ------LETI -GL------- ------ANNK LN-GILDIGT RYGN------ ---------- ---------- -------NLT L-DLRNNSIK DFTQKTGYNM NIS------- ---------- ----LAGNPI CDGT---GAT AKYC-AIQIS NDSFSSPLK- CPAMSCNSDK ---------- ---------T LS-------- ---------- --------P- TCKCSYPYTG TLHFFSLSFS NL-------- ---------- ---------- ---------- ---------- ---------- ---------- -------E-- -------N-- --SSY----- -FTTLAGSM- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------M--- ---STFLS-- ---------- ---------- ---------- -------N-G LPVD--SVSL SDPTVDV-Y- ---------- ---SYLQIEA QIF------- ------PS-- ---------- ---------- ---------- ---------- ----T-QDS- ---------- ---------- ----FNHTSI -PSIGYLL-- -----NRNPF QLQY------ ---------- --F----GPF ------FFTS ES-----YCC F-ADG----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- KK----KSSS R--------- --------TG IIIGVSVG-- ---------- -----CAVLV LL--TLCAGL Y--------- -AFR------ ---------- -----QR-K- ---------- ---------- -------MAK RA-------- ---------- ---------- ---GHSSN-P F-------ES W--------- ---------- ---------- ---------- ---------- ---------- ---DRDTSG- ---------- ---------- ---------- ---------- -A-------V PQLKGARW-- ---------F SFDEIRKCT- NNFSESN-CI GSGGY-GKVY KGTL--TAG- E-VVAIKRAQ HGS------- ---------M Q-GAFEFKTE IELL----SR I-HHKNVVSL VGFCYE---- ----QGEQML VYEYIPKGTL RESLSVE--- ---------- ---------- -PKF--QL-- AW--TRRLRI ALDAARGLAY LHELADP-P- IIHRDVKSNN ILL----DD- HL-TAKVADF GLSKLL---- -------SDE DKGHVTT--- ----Q----- ---------- --------VK GTLGYLDP-- ---------- ---------- ------EYY- M--------- -SQQ---LTE K-SDVYSFGV VLLEL-ITAR APIERG-K-- ---------- ---------- ---------- ---------- ---------- ---------- ----HI---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --VRLVAETI YDS-KDNSK- ---------- ----LYQ--- ---LIDPR-I -GPGSKL--- --------EG ---------V ----DRLFTL GMRCVNESGA ERP------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---SMGEAV- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -KEIESI--- -----L---- ---------- ---------E LASL------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --SKYTEGDL T--------- -------SSS YEDTTQVSLD DF-------- ---------- ------YND- ---KA----- ---------- ---------- ---------- ---------- ---------- ---------- --FDYSGK-- ----FPSG-- ---------- -----GMNTT Y--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC10H1G2489.2 --------ME KHLRLKT--- ---------- ------LLVL ---------- ---------- -LVLLLSISI SEQLQ----- ---------- ---------- ----SSSQAN ---------I LSRIRNL-L- NYP------- NVL------- --SN-W---- ------N--- ---------- -----N-DTD ---------F -------C-- ---------- ---------- ---------- ----NTEPSS SVTVI----- ---------- --------CY -----EDN-- ---------- ---------- ---------- --ITQ----- ---------- ---------- -LHIIGSKGA ---------- ---------- ---------- -----SQL-H --NFSIDSFV TTLVELPSLK VLRLV----- ---------- ---------- ---------- ---------- -SLGLYGPLP SK-L-SR-LS ---------- ---------- ---------- ---------- -------S-L EILDLSSN-- ---------- ---------- ---------- ---------- ------FF-- ----HS-NIP RE-------- ---------- ---------- ---------- ---------- -ISSL-T--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------SLQS -LILDGN--- ------KFT- G-RLPNGL-- GSLVV-LAV- ---------- ---------- -LS------- ---------- ---------- ---------- ---------- -V-KNN---- ---------S LDGH--LPDM ---------- ---------- ---LG----- NLHNLRVLSL SRNNFTG--- ---------- DVPDLS---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- G--------- ---------- ---VENLQ-V LDLEDNS-LG PKFPQVS--- ---------- ---------- ---------- ---------- --------SK IQSIVLRN-- ---------- ------NKFT AGI------- ---------- ---------- ---------- ---------- ---------- --TE-KVQ-- SYHQ------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----LEHMDI SSNR------ ---------- ---------- ---------- ---------- --FM------ -G-------- ---------- ---------- ---------- ---PF-PPSL LSLPSITY-- LNIAG----- ---------- ---------N KLTGMLFED- ---------- ---------- NQ------CN A--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -------GLD FVDLSTNLLS G--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----RL---- ---------- ---------- --------P- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -----SC--- ---------- ---------- ---------- ---------- -------LLT GPKH------ ---------- ---------- ---RIVRYSN NCL-ATGDG- ---TQHPF-- ---------- ---------- ---------- ---------- --------S- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --F------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- CRN------E ALAVG----- ------ILPH ---------- ---------- -----HHKHI ---------- ----PGS-KV VLALIICGS- ---------- ----IIGGVV LV--CATIIV VR-------K FLAK------ ---------- -----IATPR KT-------- ---------- -TRSIVENAA STYTSKL--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- FTDANYVTRT MK-------L GTLSLPS--- ------YRTF SSEELKVAT- NNFDAAT-FI GNSSD-DQLY RGQL--KDG- S-YITIRCLQ TKRK------ ---------- -NSSQNFMYH IELM----SK L-RHHHLIST LGHCFE-CYL DDSSVSRIFL VFEYVSNGTL RSWISEKHAK ---------- -------GR- -------L-- TW--TQRIAA AIGVARGMQF LQTGNVP-G- VFSNNIKITD ILL----DQ- NF-VAKICSY NLPILN---- -------ENV MEQ------- ---------- ---------- ---------- ---------- ---------- ---------- -------KS- T--------- -RAN---YEE K-LVVYDFGV ILLEI-ISGK QINTKN---- ---------- -------EVR VTQNQ----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -------LQ- ---------- --ESIMSN-- ---------- -AMS------ ----RKN--- ---VVDPE-I -RNSCSD--- --------ES ---------L ----KTMIEI CCRCLEQDTE DMP------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---SVEDVI- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------W NLQFA----- ---------- ---------- ---------- -AQVED---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------S WRKDSSSSDA SPISHLY--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -----SF--- ---------- ---------- -------KLN LSRN------ ---------- ---------- ---------- ---------- ---------- ---------- -----SNSTH V--------- ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC03H1G1508.2 --------M- ---------- -----FLF-L VNCLF-FFA- ---------- -------NFF -AVFSTSSP- ---------- ---------- --------Q- -------DSV ---------H LLGFHSS-L- PELS------ QQL------- --LP-W---- ------N--- ---------- -----Q-SVS -H-------- -------C-- ---------- ---------- ---------- --------Q- WKGVS----- ---------- --------C- -----YSD-- ITSHVKSLIL TDLLLPGTLD KAFPNLCRLL R-LVS----- ---------- ---------- -LDLSGNHF- -----TGG-- ---------- ---------- --IP-DMLAN ---------- -----CSQLD TILLN----- ---------- ---------- ---------- ---------- -ENRFSGSIP PE-I-FK-SS ---------- ---------- ---------- ---------- -------K-L IKLDLGLN-- ---------- ---------- ---------- ---------- ------QL-- ----TG-TIP SE-------- ---------- ---------- ---------- ---------- -VSLS-T-NL QHLGLW-NNF LSGNI-P--K ELFDLP--NL THLHLYTNE- LTGPLPDFPF SCSLSEFFIY ENRFSGS--- ---------- ---------- -LPITLGNCH NLTSFSASSA HLGGVISPEV FRDLS-NLEF -LYLDEN-N- -------FE- G-GIPETLWD GSLQE-LALS LNKFNGS-IS EKIGGSLQIN YID------- ---------- ---------- ---------- ---------- -L-SVN---- ---------K LTGQ--LPRS ---------- ---------- ---VG----- RLKNLNKLFL YDNMLSG--- ---------- SLPAEL---- ---------- ---------- ---------- ---------- ---------- ---------- -G-------- ---------- ---------- -----NCTSL VAISL----- --ATNFISGE IP-QEL---C N--LHSLI-K FQVYGNQ-IQ GRIPECT--- ---------- ---------- ---------- ---------- -----GRISG LEELDLSE-- ---------- ------NRLI G--------- ---------- ------KIPP GITNMTK--- LVFLSLAHNN L------TGE V-PP-NLGKN NFPGL----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----FKV-DL GYNN------ ---------- ---------- ---------- ---------- --LS------ -G-------- ---------- ---------- ---------- ---PI-PSEL CNGNRLGV-- LVLENNSFNG SFPTYLAKCE SLYRVKLPNN NLQGSIP-D- ---YIEK--- ---------- --------NE K--------- ---------- ---------- ------ISYL -NV------- ------RGNK LA-GRIPAAF GYWT------ ---------- ---------- -------NLS TIDLSKNMFS G-----SIPA EIGK------ ---------- ---------- ---------- ---------- ---------- -----LQNLV ------RLNI SSN-RL-TGK I--------- ---------- --------P- ---------- ------LQLS YS-------- ---------- ---------- ---------- ---------- ---------- ---------- -------VKL -AELDLSN-- --NNL----- -SGRIPKEI- ---------- ---------- ---------- ---------- ---------- ---------- ---------A SSSV------ ------L--- ---TNLLL-- ---------- ---------- ---------- -------Q-D ---N--KLSC SLPDTFSSS- ---------Q KL-VKLQLGD NLL-EGSI-- ------PC-- ---------- ---------- ---------- ---------- --------SL SKLSEPNVAL NLSMNKFSGQ IPRCLSNLDN LEILDISS-- -----NNLSG AIPLEMDKMR SLSFLNISFN N-L-SGKVPI L-WEK-RLSS HP----GTSQ --GNP----- ---------- --------GL C--LSDTESS S--------- CKH------V KKS------- ---------- ---------- ---------- ---------- ------Q--- ---RNWKTLA GVISGCVFS- ---------- ----MAVIAA AI--YLLVTR IQ-------- HPSL------ ---------- -----LN-KH QLV------- ---------- -----KYQA- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -E-------I EDLP------ ------DR-I NFEDIVRAT- EGWSEKY-VI GRGKH-GTVY KMESA-KSK- K-LWAVKKVD LAQR------ ---------- -----AFSDE MRTL----NS V-RHRNLVRL GGHCTR---- --HGYGF--I LTEFIPGGTL HDVLHQR--- ---------- ---------- KPPV--VL-- DW--EPRHRI ALGVAQGLSY LHHDSVP-Q- IIHRDLKSDN VML----DT- EM-EPKIGDF GIAKTVSDS- ---------- -DENSTN-S- ----K----- ---------- --------IV GTLGYIAP-- ---------- ---------- ------ENA- Y--------- -SVQ---LTE K-SDVYSYGV LLLEL-FCRK MPVDPS-FE- -------E-- -------GLD IVSWV----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --RKNLH--- ----RSDNN- ---------- ----FLH--- ---LLDEE-I -SFWYIEE-- -QWKAL--KM ---------V ----YLALQ- ---CAELEAS TRP------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---AMRDVV- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------R SL-------- ---------- ---------- ---------- ---VELN--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --------HR CKREE----- ---------- ---------- ---------- ---------- ---------- --------MK L--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC07H1G2576.2 ---------M KKA------- -----ALPWR WASYALILIY S--------- ---------- ---LGIIF-- ---------- ---------- ------EIAV AQTTDPSEAR ---------I LNSMFQN-WG I--------- -SA------- --TNQW---- ---------- ---------- -----NISGE -L-------- -------CSG AAIDST---- ---------- ----SILD-- -F-------- NPSIK-CD-- ---------- --------CS AN---NRT-- ---------- ---------- -----RC--- H-ITG----- ---------- ---------- -LRVYALDV- -----MGE-- ---------- ---------- --IP-DELWS ---------- -----LTFLD DLNLG----- ---------- ---------- ---------- ---------- -QNYLTGTLS PS-I-GN-L- ---------- ---------- ---------- ---------- ------TR-M KWLTFGVN-- ---------- ---------- ---------- ---------- ------AL-- ----SG-EIP KE-------- ---------- ---------- ---------- ---------- -IG------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --SLGTN-N- -------FS- G-PLPSEL-- GNLTK-LTQ- ---------- ---------- -IY------- ---------- ---------- ---------- ---------- -L-NSA---- ---------G VSGP--IPLT ---------- ---------- ---LA----- RLQDLEQVWT SDNAFTG--- ---------- RIPDFI---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --------GN N--WTKLT-V LRFEGNA-FE GPIPASF--- ---------- ---------- ---------- ---------- -----SNLTT LTDLRISDL- ---------- ------SNGS SSL-DF---- ---------- ---------- -LRNMKS--- LSKLVLRNNN I------SGS I-PS-NIG-- EYQS------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----LSLLDL SFNN------ ---------- ---------- ---------- ---------- --LT------ -G-------- ---------- ---------- ---------- ---RI-PDAL FNLTLLTH-- LFLGD----- ---------- ---------N KLTGALP-A- ---QKIR--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -----SLQT- ---------- ---------- ---------- ---------- ---------- -IDLSYNELS -----GNFPS WINENLQ--- ---------- ---------- ---------- ---------- ---------- ---------- -------LNL VANNF-TTEQ IDQSDSSSL- -PSGLNCLQR NFPCNRGRP- ---------- ----I---YS DF-------- ---------- ---------- ---------- ---------- ---------- -----AIKCG G--------- -GRAIRSSDQ --ISYERENE TLGPATYFMT STGR------ ---------- ---------- ---------- ---------- ---------- ------WAVS NAGLHSDRPN QSFTSFT--- --SSQFTN-- ---------- ---------- ---------- ---------T LDS---ELYQ TARISAGSLR YYGLGLE-NG NYTVTLHFAE SEI-LNPPT- -----WRS-- ---------- ---------- ---------- ------VG-- --------RR V--------F DIY------- ----VQGIRQ LKDFDIKREA GGRSLAAVQR RFTAQVSDNH LEIHLFWAGK G---TCCVPI QGTYGPSISA IS---ATPDF E--------- ---------- ---------- ---------- ---------- ---------- ---------- --------PS V--------- ---------- ----SNQPPT T--------- ----KKNRTG LIVGIVVGVG ---------- ----VISLIS LF--AVYYLI QKRK------ --QQ------ ---------- -----KALED EEF------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --------MG ID-------T RP-------- --YT-----F SYSELRAAT- GDFSSSN-KL GEGGF-GPVY KGTL--EDE- R-VVAVKQLS VASH------ ---------- -QGKSQFVAE IATI----SA V-QHRNLVKL YGCCIE---- ----GDRRLL VYEYLENKSL DQALFEK--- ---------- ------GSL- ------YL-- DW--PTRFQI CLGVAKGLAY LHEESRV-R- IVHRDVKASN ILL----DA- DL-NPKISDF GLAKLY---- --------DD KQTHINT--- ----R----- ---------- --------VA GTIGYLAP-- ---------- ---------- ------EYAM R-GH------ -------LTE K-ADVFGFGV VALEI-VSGR TNSDES---- ----LEED-- -------KIY LLEWA----- ---------- ---------- ---------- ----WQ---- ---------- ---------- ---------- ---------- ---------- -------LH- ---------- ---------- ---------- ENKR------ ----ETE--- ---LVDAN-L --SEFDV--- --------EE ---------V ----KKVIGI ALLCTQTSPG LRP------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---SMSRAI- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -AMLTGDAE- -----V---- ---------- ---------- ---AAVTSRP G--YLTDW-- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- KFKD------ ---------- -------TTT FMSDHSSQMQ NSSVG----- ---------- --TSTAAT-- ---TNYSPSG ---------- ---------- ---------- ---------- ---------- -------QDT PMLSDI---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----IGEGR- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC09H1G1332.2 ---------- ---------- -----LYFNQ GKSFL-LLSP QVF------K MKG---LRYC IYVLTAAIHC YMLL------ ---------- --------VA AQTTDPSEVS ---------A LISVKGS-L- IDNM------ KHL------- --ND-W---- ------K--- ---------- -RG------D -P-------- -------C-- ---------- ---------- ---------- -------TSH WTGVF----- ---------- --------C- -----NISDA DG-------- --YL------ ---------- H-VRE----- ---------- ---------- -LRFMNMNL- -----SGS-- ---------- ---------- --LS-PELGQ ---------- -----LSHLR ILNFM----- ---------- ---------- ---------- ---------- -WNNLTGSIP KE-I-GS-IT ---------- ---------- ---------- ---------- -------T-L KLLLLNGN-- ---------- ---------- ---------- ---------- ------QL-- ----SG-SLA DE-------- ---------- ---------- ---------- ---------- -LGNL-S-NL NRFQID-QNE ISGEI-P--K SFSNLN--KI RHIHFNNNS- LS-------- ---------- -----GQ--- ---------- ---------- -IPHELSN-- ---------- ---------- ---LS-TILH -LLLDNN-N- -------LS- G-YLPPEF-- SALAD-LAI- ---------- ---------- -LQ------- ---------- ---------- ---------- ---------- -L-DNN---- ---------N FSGSE-IPAS ---------- ---------- ---YG----- NLSSLLKLSV RNCSLQG--- ---------- SIP------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----DF---S R--IANLS-Y LDLSWNQ-LS GSIPQ----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------NKLS NN-------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----MTTIIL SHNR------ ---------- ---------- ---------- ---------- --LN------ -G-------- ---------- ---------- ---------- ---SI-PKNF SLLPSLQK-- LSLEN----- ---------- ---------N FLNGSIS-T- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -DI------- -----WQNKI FN-------- ---------- ---------- -TT------- -------SRL VIDLRNNSVS NISGAFEPPV NV-------- ---------- ---------- ---------- ---------- ---------- ---------- ------TLRF QSN------- ---------- ---------- --------P- ICSS------ ------TSIR NI-------- ---------- ---------- ---------- ---------- ---------- -----GKYCG P-------DF GADDDEPS-- --NSTN---- PSGVCPIHA- ---------- ---------- -------CPT DN-------- YYEYVPASPK P-CFC----- ---------A S--------- -----PLRIG ---YRLKS-- ---------- ---PSI---- ---------- -SYFDPYK-Q LFES--YVTS SLQLDLYQLW IDSYFWEKGP RLRMYLKL-- ---------- -----FPV-- ---------- ---------- ---------- ------VGDN T----FNESE I--------- ---------- ----LRISEI FASWEFQG-- -----SHLFG --PYELLNFT ---------- --L------- ---------- ------LGPY SHLNP----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----E----- ---------- MKG------- ---------- ----KRQSKG VVIACIVAAG ---------- ----AFAAFV SS--IATILI TRRR-AKYQK ILSR------ ---------- -----KR--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --------LS SS-------L SIKVDGV--- ------KS-F TFREMTSAT- NNFDTST-QV GEGGY-GSVF RGIL--ADK- T-VVAIKRAK VGSL------ ---------- -QGQKEFLTE IELL----SR L-HHRNLVVL LGYCDE---- ----EGEQML IYEFMPNGTL RDWLSAKC-- ---------- -------KK- ------NL-- KF--GARLGI ALGASKGILY LHTEADP-P- IFHRDIKASN ILL----DS- KL-TAKVADF GLSRLAPVQD ------DEGL LPNHVST--- ---------- ---------- -------MVK GTPGYLDP-- ---------- ---------- ------EYF- ---------- LTRK---MTD K-SDVYSLGV VFLEI-LTGM HPIS------ ---------- ------HGKN IVREV----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --KMAHK--- ---------- -SGV------ ----MFS--- ---IMDKN-M -GSY------ -------PSE C--------A ----EKMVEL ALKCCQDKPE DRP------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---SMLEVV- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -RTLET---- ---------- ---------- ---------- ----ILQMMP YTDTDPLD-- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------N KASFSETTSS ASFSNTR--- ---------- -----SGDLF ISSSNVSGGD L--------- ---------- ---------- ---------- ---------- -----ISGVT LNITPR---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC10H1G1670.2 ---------- ---------- ------MRHQ LGYLS-FLLF ---------- ---------- -LLFHSTFQQ H--------- ---------- ---------- ------EDRL ---------A LLQLRSS-L- ---------- GLRA------ --RE-W---- ---------- ---------- -----PIKGT -P-------- -------C-- ---------- ---------- ---------- -------SN- WRGIS----- ---------- --------C- -----NNG-- ---------- ---------- ---------- R-VTG----- ---------- ---------- -INISGFKRT ----RTGNQN P--------- ---------- -QFLVDSLQN ---------- -----LTLLE SFNAS----- ---------- ---------- ---------- ---------- -NFALLGSIP DW-F-GIGLA ---------- ---------- ---------- ---------- -------S-L QVLDLSFC-- ---------- ---------- ---------- ---------- ------SI-- ----TG-AIP ST-------- ---------- ---------- ---------- ---------- -IGNL-R--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------SLAV -LYISNN-G- -------LS- G-MVPSSL-- SQLLS-LSV- ---------- ---------- -LD------- ---------- ---------- ---------- ---------- -V-SHN---- ---------A LGGS--IPAS ---------- ---------- ---FG----- SLGNLTLLDM SSNVLSG--- ---------- AIPPVI---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----GTLSQL KFL------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 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---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -----KSPKN VIISAAVLG- ---------- ----VVGFIA TVM-LFVVLL IC-------C C-KRGVTNQ- ---------- -----RV-TG VGP------- ---------- ---VPTTASP PPP------- ---------- ---------P GPSLKFSS-- ---------- ---------- -----L---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -----GVA-F NYQQILQTA- GHFSDVN-LI KHGHS-GDIF RGIL--KGG- V-HVVVKRID SSS------- ---------- -VKKEAYLLE LDFF----SK V-SHSRVVPF LGHCLE---- ---SENEKFL VYKYMPNGDL SSSLLRKNNA ---------- -------DD- DSLQ--SL-- DW--ITRLKI AIGVAEGLSY LHHECNP-P- LVHRDVQASS ILL----DD- KY-EVRLG-- SLSEVCAQEG --------DT HQNKISR--- ---------- -M-------- ---------- ----LRLPQT S--------- ---------- ------EQG- ---------- ASGTP-NATC A-YDVYCFGK VLLEL-VTGK LGISSS---- ---------- ------SDAT IKDWL----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --DKSLSCIS M---DDKEL- ---------- ----VTN--- ---IVDPF-L -IVDDDL--- -------LKE ---------V ----WAMAIV ARSCLNPKPS RRP------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---LMRYIL- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -KALENPLK- -----V---- ---------- -------VRQ EHAISERLRA TSSRGSWNAT L--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -------FGS WRHSFSDIVA PP-------- ---------- ---------A NKVEG----- ---------- ---------- ---------- ---------- ---------- ---------A SSFKKSATMG -----SQGIG QV-------- -AE-GGPSFS TGRHS----- ---------- --KEIFPEPL DVQD------ ---------- ---------- ---------- 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-------FT- K-EIPKGF-- ELMEN-LEV- ---------- ---------- -LD------- ---------- ---------- ---------- ---------- -L-HGN---- ---------M FDGN--LDAE ---------- ---------- ---ML----- LLTTATHVDL SGNLLVN--- ---------- TASQQQ---- ---------- ---------- ---------- ---------- ---------- ---------- -KFLP----- ---------- ---------- ----GLSESV KYLNL----- --SHNQLKGS LVSGNE---A QI-FGNLK-V LDLSYNQ-LS GELPS----- ---------- ---------- ---------- ---------- ----FNFVYD LQVLKLAN-- ---------- ------NLFS GFI-PNDLLK GDALL----- ---------- ---------- LTELDLSGNN L------TGS I-SM-----I TSTT------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----LRMLNL SSNA------ ---------- ---------- ---------- ---------- --LS------ -G-------- ---------- ---------- ---------- ---EL-PFVT ---GTSAV-- LDLSK----- ---------- ---------N QFKGNLT--- ---RMLK--- ---------- --------WG N--------- ---------- ---------- ------IEFL -DL------- ------SQNR LN-GNIPEVT AQFL------ ---------- ---------- -------RLY HLNLSSNTLT G-----SLPK VISQ------ ---------- ---------- ---------- ---------- ---------- -----FPKIT ------VLDL SFN-QL-DGP L--------- ---------- --------L- ---------- ------TSLL TL-------- ---------- ---------- ---------- ---------- ---------- ---------- -------PTI -EELHLQN-- --NAL----- -VGSIDFSLP A--------- ---------- ---------- ---------- ---------- ---------- ---------S T--------- ---------- ---PKLRV-- ---------- ---------- ---------- -------L-D LSHN--QLAG YFPDGFGSL- ---------I AL-QVLDISG NNF-SGSL-- ------PT-- ---------- ---------- ---------- ---------- --------S- ---------- ---------- ----MGNVSS LTSLDVSE-- -----NHFSG ELPKNLPN-- SLQSFNASLN D-F-SGVVPE ------NLRK FP----LSSF YPGNSQL--- ---------- ---------- ---------- ---------- ---------- ---------- ------QFPN ---------- ---------P PSG-SGQAST EK-------- ---HKSRQLK TIIKVVIIVA ---------- ---CVVVLVV LI--MLAIFV FY-------L RASRNSQA-- ---------- -----HV-TD KDI------- ---------- -----RRQTQ SNPSGFS--- ---------- ---------- -----SRE-- --GAVVSAQD VTA------- ---------- --------AS RKASSSEVIS ADEKT----- ----TGFSPS KTSHFTWSPE SG------ES YTAESLA--- ---------- ------DNLA GE-------L FFLDDTI--- -------S-F TAEELSRAPA E-------VL GRSSH-GTSY RATL--DNG- L-LLTVKWLR EGVA------ ---------- -KQRKDFTKE AKKF----AN I-RHPNVVGL RGYYWG---- --PTQHEKLI LSDYISPGSL SNFLY----- ---------- -------DR- PGRKGPPL-- TW--PQRLKI SVDIARGLNY LHFDR---E- VPHGNLKATN ILL----DGP DL-NARVGDY CLHRLMTQAG ---------- ---------- -TIEQ----- ---------- ----IL--DA GVLGYRAP-- ---------- ---------- ------ELA- A--------- -SKKP-VPSF K-SDVYAFGV ILLEV-LTGK CAGDVV---- ---SGEDG-- -------GVD LTDWV----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --RLKVA--- ---------- -EGG------ ----GFD--- ---CFDNA-L -SSE------ MGNQTT-EKQ ---------M ----KEVLAI ALRCIRSV-S ERPAMATFCR LRSLLAPQKL VCSVSPFYPM RSYSSSPFGR IGFIGLGNMG ARMADSLIKD GYEVAVHDIN YNVMKMFSAK GVLTEDSPLK VAETSDVVIT MLPSSNHVLD VYTGKNGFLS GGNLLRPRLF IDSSTIDPQT SRKVSAAVSN CSLIDKRDGL KAPAMLDAPV SGGVLAAENG TLTFMVGGPE EAYLAAKPLF LSMGKNTIYC GGSGNGATAK ICNNLAMAIS MLGVSEAFAL GQSLGIEAST LTKIFNSSSA RCWSSDTYNP VPGVMDGVPS SRNYIGGFAS KLMAKDLNLA AASAKDIGFK CPLTSQAEKI FTELCNNGHE AKDFSGVFR- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------YYYS GKDEQ----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC02H1G2263.2 --------MA GSG------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -------N-- ---------- ---------- ---------- ---------- ------AF-- ----SG-NLP PEIFNLTDLQ IFNVAGNQLS GEI------- ---------- ---------- -PGELPQ-SL RYFDLS-SNL FSGDI-P--R KFSDRS--QL LLINLSYNR- FS-------- ---------- -----GE--- ---------- ---------- -IPASLGR-- ---------- ---------- ---LQ-QLQY -LWLAYN-N- -------LV- G-TLPSAI-- ANCSS-LVH- ---------- ---------- -LS------- ----A----- ---------- ---------- ---------- ---EGN---- ---------A IGGL--IPAA ---------- ---------- ---IA----- ALPKLQVISL SYNNLSG--- ---------- SLPASL---- ---------- ---------- ---------- ----FCNVSI ---------- ---------- ---------- YPPSLRIVQL GFNAFTNIVK QESSKCFSSL QILDL----- --QHNQIHGE FP-LIL---T N--ISALT-S LDLSWNL-FS GKIPSAI--- ---------- ---------- ---------- ---------- -----GNLWR LEELRMTN-- ---------- ------NS-- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --FE------ -G-------- ---------- ---------- ---------- ---TI-PSSI GTLYKLTV-- VDLSG----- ---------- ---------Q NFSGEIP-F- ---DLAG--- ---------- --------LP N--------- ---------- ---------- ------LQVI -AL------- ------QENK LS-GNVPEGF SSLL------ ---------- ---------- -------GMQ YLNLSSNSIS G-----HIPS TFGF------ ---------- ---------- ---------- ---------- ---------- -----LTSLV ------VLSL SNN-HI-NGS I--------- ---------- --------P- ---------- ------PDLG NC-------- ---------- ---------- ---------- ---------- ---------- ---------- -------SAL -ENLNLHS-- --NSL----- -SGQIPADL- ---------- ---------- ---------- ---------- ---------- ---------- ---------G R--------- ------L--- ---SHLSV-- ---------- ---------- ---------- -------L-D LGRN--NLTG EVPVDISNC- ---------S SL-TSLVLDL NHL-SGNI-- ------PE-- ---------- ---------- ---------- ---------- --------S- ---------- ---------- ----LSRLSN LTVLDLST-- -----NNFTG EIPANLTMLS SLVSFNVSNN N-L-GGQIPE ---ML-GSRF NN----SLDY A-GNQ----- ---------- --------GL CGEPLERR-- ---------- CET------S ---------- ---------- ---------- ---------- ---------- ------G--- -----DGGNK LIMFIAVAA- ---------- ----SGALLL LS--CCCLYT YNFL-----R WRRK------ ---------- ----LKE-KA AGE------- ---------- -----KKHSP ARASSRTS-- ---------- ---------- ----GGRG-S GE-------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -------NGG PK-------L VMFNNKI--- ---------- TLAETIEAT- REFDEEH-VL SRTHY-GVVY KACY--NDG- M-VLSIRRLS NGT------- ---------- -LGENMFRKE AESL----GR V-KHRNLTVL RGYYAG---- ---PPNLRLL VHDYMPNGNL ATLLQEAS-- ---------- -------HQ- D-GH--VL-- NW--PMRHLI ALGIARGLAF LH---SS-S- MVHGDVKPQN VLF----DA- DF-EAHLSEF GLGKLV---- --VAT---PT EPST-S---- ----T----- ---------- --------SV GTLGYISP-- ---------- ---------- ------EVA- L--------- -TGE---TTR E-SDAYSFGI VLLEL-LTGK RPL--M-FT- -------Q-- -------DED IVKWV----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --KRQLQ--- ---------- -RGQ------ ----ISE--- ---LLEPG-L -LELD----- PESSEW--EE ---------F ----LLGIKV GLLCTAPDPL DRP------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---TMADIV- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -FMLEGC--- ---------R VGPDIAS--- ---------- ------SADP TCQ------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------P SPA------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC05H1G2113.2 ---------- --MSVAYRYS NHNRHYRRHH HHLLI----- ---------- ---------- LVVLLLLVVV PVK------- ---------- ---------- --S-DSSEAE ---------I LFRFSKS-L- Q--KN----G AT-A------ ---N-W---- ------N--- ---------- ----TKV--S -P-------- -------CDK NTDK------ ---------- ---------- -------PN- WDNVI----- ---------- --------CE ---------- NG-------- ---------- ---------- F-VFG----- ---------- ---------- -LQLESKGL- -----SGT-- ---------- ---------- --IDVDALKD ---------- -----LPNFR TISVM----- ---------- ---------- ---------- ---------- -NNNFEGPLP NL---SK-LA ---------- ---------- ---------- ---------- -------G-L KTAYFTNN-- ---------- ---------- ---------- ---------- ------KF-- ----SG---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --QIDNTL-- ---------- ---------- ---------- -FE------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- GMHWLKKLHL ANNQLSG--- ---------- KIPSVL---- ---------- ---------- ---------- ---------- ---------- ---------- -GQ------- ---------- ---------- ---------- ---------- ---------- ---------- ---LPKLT-E LRLENNK-FE GQIPD----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -----FVQER ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----LMDMNF ANNS------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -LEGPIPHG- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------L--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 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H--------- -SGR---ITR K-NDVWTLGI LILEI-ITGK FPSNFL---- -----QQGKG S------DTD LATWV----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --RSVVNE-- ---------- -DMT------ ----EVD--- ---VFEKE-M -RGTT-NSE- --------GE ---------M ----MKLLKI ALGCCDLDME KRF------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---DMKEAM- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -ERIEEVK-- ---------- ---------- ---------- ---------- ERD--GD--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -------DDF YSTRGLS--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------DD-- ---------- -------YTQ VSMNI----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC12H1G2368.2 ---------- ---------- ---------M LKIAL-FFFF ---------- ---------- -LFFYSVLSN QISN------ ---------- ---------- ------LEHK ---------A LLDLRSS-L- ---------- GIRA------ --KN-W---- ---------- ---------- -----PRKSN -P-------- -------C-- ---------- ---------- ---------- -------TN- WTGIH----- ---------- --------C- -----NND-- ---------- ---------- ---------- K-VVA----- ---------- ---------- -IQLTGLRRI ----HKGNMS P--------- ---------- -QFAVDSLVN ---------- -----FTHLT SFNSS----- ---------- ---------- ---------- ---------- -GFVLSGPIP DW-F-GQKLT ---------- ---------- ---------- ---------- -------Q-L KQLDLSSS-- ---------- ---------- ---------- ---------- ------SI-- ----LG-SLP TS-------- ---------- ---------- ---------- ---------- -LGSL-S--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------NLDF -LSLFNN-S- -------IT- G-TVPLEL-- GKLSS-LRV- ---------- ---------- -LN------- ---------- ---------- ---------- ---------- -L-SWN---- ---------S LTGS--IPSS ---------- ---------- ---VS----- DIKNLSVLDL SSNFLSG--- ---------- QIPVEF---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----GSFLGL ELLNL----- --SNNSLSSY IP-SEI---S N--LSALV-E LDLGYNY-LS GSLPEGL--- ---------- ---------- ---------- ---------- -----LRMRN LSKLLVGN-- ---------- ------NELE GAL-SSTL-- ---------- ---------- -FTSNDSV-- LEYINLSWNR F------EGK V-PD-VLW-- SLSDH----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----LRVLDI SGNN------ ---------- ---------- ---------- ---------- --FT------ -G-------- ---------- ---------- ---------- ---VV-SN-S TYFSVTGA-S YNLSN----- ---------- ---------N LFYGNVT--- ---FDVR--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -------SFQ SIDLSKNYFQ G-----LAPD --KS------ ---------- ---------- ---------- ---------- ---------- ---------- ------GVRV MDN-CF---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -------AGL LNQRSLDD-- -CSKFYAD-- -RGLVFVDG- ---------- ---------- ---------- ---------- ---------- ---------- ---------G I--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------Q--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -------TPV Q--------- ---R------ --ASK----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 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RHC01H1G4178.2 --------MS ASANF----- -----FRPCP ILLLC-FF-- ---------- ---------- --IFLIS--- ---------- ---------- ---------- -PSHQQDELQ ---------L LMNFKST-LK TTQIS----- HLF------- --DT-W---- ------T-P- ---------- -----QNN-- -I-------- -------C-- ---------- ---------- ---------- --------N- FTGVF----- ---------- --------C- -----DSD-- SK-------- ---------- ---------- L-VKE----- ---------- ---------- -INLSEQNL- -----SGV-- ---------- ---------- --VSFDSLCS ---------- -----LKSLE KISLG----- ---------- ---------- ---------- ---------- -TNYLYGRVS DH-L-KN-CT ---------- ---------- ---------- ---------- -------E-L QYLDLGNN-- ---------- ---------- ---------- ---------- ------SF-- ----SG-EVP N--------- ---------- ---------- ---------- ---------- -LSSL-S-QL EFLNLN-RSG FSGSF-P--- WS-------- ---------- ---------- ---------- ---------- ---------- ---------- ----SLGN-- ---------- ---------- ---LT-SLTF -LSLGDN-S- -------FNK S-PFPLEI-- LNLDK-LYW- ---------- ---------- -VY------- ---------- ---------- ---------- ---------- -L-TNS---- ---------S IEGQ--IPEG ---------- ---------- ---IG----- NLTLLENLEL SYNDLSG--- ---------- KIPDGI---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----IKLTKL KQLEI----- --YSNGLTGK FP-VGF---G N--LSSLV-N FDASSNN-LQ GDL-SEL--- ---------- ---------- ---------- ---------- -----KSLSL LESLQLFE-- ---------- ------NHFS GEI-PVEF-- ---------- ---------- --GNF-K--- FTELSLYRNM F------SGS L-PQ-NIG-- SWAE------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----LQYIDV SENM------ ---------- ---------- ---------- ---------- --FT------ -G-------- ---------- ---------- ---------- ---SI-PPDM CKKGSMTD-- LLLLQ----- ---------- ---------N NFTGGIP-S- ---NYAT--- ---------- --------CL S--------- ---------- ---------- ------LQRL -RV------- ------SNNS LS-GVVPSGI WSLP------ ---------- ---------- -------DLE IIDLTLNLFE G-----PVTS NIGE------ ---------- ---------- ---------- ---------- ---------- -----AKSLA ------QLFL AYN-RF-NGQ L--------- ---------- --------P- ---------- ------QTIS EV-------- ---------- ---------- ---------- ---------- ---------- ---------- -------SSL -VAINLSA-- --NQL----- -SGDIPAAI- ---------- ---------- ---------- ---------- ---------- ---------- ---------G E--------- ------L--- ---KKLNT-- ---------- ---------- ---------- -------L-H LEYN--LFSG SLPDSIGSC- ---------V SL-CEINLAG NSL-SGAI-- ------PE-- ---------- ---------- ---------- ---------- --------S- ---------- ---------- ----LGSLRS LNSLNLSD-- -----NTLSG QIPATLSSLR -LSLLDLSNN R-L-SGSIPD ---S--LSIK AF----SNSF L-GNP----- ---------- --------DL C-SENFGSLR P--------- CS-------- ---------- ---------- ---------- ---------- SDP--HTSRD ---------- --------HR TVMLC-LIA- ---------- ----GVVVLV LS--LTCFVY ---------- VKFK------ ---------- -----HN-NQ NTP------- ---------- -----VKRL- ---------- ---------- ---------- -------D-S W--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -D-------I KQF-HVL--- -------S-F SEDQVL---- KALKQEN-LI GRGGS-GNVY RLVL--NCG- K-QLAVKHIV KSDSGDQKSY RDSSAILVKE NRRSKEYDAE VTTL----SS I-RHVNVVKL --YCSIT--- ---SEDSNML VYEYLTNGSL WDRLH----- ---------- -------TS- QKV---KM-- DW--LVRYDI ALGAAQGLEY LHHGYDS-P- VMHRDVKSSN ILL----DE- QM-KPKIADF GLAKVL---- -HVNG---TK --DSSQ---- ----V----- ---------- --------VA GTHGYIAP-- ---------- ---------- ------EYA- Y--------- -TTK---VTE K-SDVYSFGV VLMEL-VTGK KPVDAE-FG- -------E-- -------NSD IVQWV----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --CSKIR--- ----NNTSM- ---------- -----ID--- ---LVDSS-I -F-E------ -GFKE----D ---------A ----VEVLKI AVHCTSRTPA LRP------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---SMRMVV- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -HMLEEA--- ---------- ---------- ---------- --------EP C--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------K LTNVVVNSPN EDG------- ---------- ---------- ---------- ---------- -RKQG----- ---------- ---------- ---------- ---------- ---------- ---------- --LAN----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC12H1G0247.2 --------MD GK-------- ---------- RFVVC-CL-- ---------- --------NL EILVWIVLAF A--------- ---------- ------VQ-L SNEANPGDVA ---------A INNLYAS-L- GSP------- S-L------- --PG-W---- ------G--- ---------- -----AVGGD -P-------- -------CNG ---------- ---------- ---------- --------L- WQGVE----- ---------- --------C- -----D---- NG-------- ---------- ---------- N-ILT----- ---------- ---------- -IRLNAANL- -----GGE-- ---------- ---------- --LG-DNLGS ---------- -----FSSLK IIDLS----- ---------- ---------- ---------- ---------- -NNHIGGSIP S--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -------NLP ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------V--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------TLRN -IFLSAN-A- -------FT- G-SIPTSL-- SSLSQ-LSA- ---------- ---------- -MS------- ---------- ---------- ---------- ---------- -L-NAN---- ---------H LTGE--IPDS ---------- ---------- ---FQ----- GLTALVNLDL SSNNISG--- ---------- SLPPSV---- ---------- ---------- ---------- ---------- ---------- ---------- -R-------- ---------- ---------- ---------- ---------- ---------- ---------- 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---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --NS--SIAP LPPPTSS-T- ---------- ---------- ---------- ------AP-- ---------- ---------- ---------- ---------- ----PISGS- ---------- ---------- ----PTSAQT ---------- ---------- --PSS----- ---------- -----QSKPK ------TQAD GP-----SAS A-ESS----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- STG--KKKSL S--------- --------AK RVVWISIAA- ---------- ----VLSFII LV--LAILLC LP-------K CLRK------ ---------- -----WH-ET QRT------- ---------- -----PKHHE IAPYMGAREN LGDSGSLVQP GHDIEKAPLV VTPK-EKQ-P R--------- ---------- ---------- ----RPAPIP KPQDEQQVNV QTMSAVPKKD -DSEINLGRL DID------L TPPPPPPPPP LTLP---LQR VIVEPIAPAE DTATRLPTRP LP-------L TSVKS----- ---------Y TIASLQQYT- NSFSQDN-LL GSGML-GSVY RVEL--PNG- K-LLAVKKLD KRVC------ ---------D QQKDDEFLDL VNNI----DR I-RHANVVEL MGYCAE---- ----HGQRLL VYEYCCNGTL QDALH----- ---------- -----FDDE- 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---------- ---------- ---------- ------VPKY -NF------- ------SENH LN-------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- CGLN------ ---------- ---------- -FSRRCVSDS ---------- ---------E GS-------- ---------- --------P- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---S--KS-- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -------KT- ---------- --------GL VIGIVGGF-- ---------- -----LGIIL LG--GLMLFF W--------- 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---------- ----TYKVTL H--------- ---------- ----FAEISS -RKYRLSH-- -----GKTRR VFDVEIQGTK VLTSFNIEAE AERQAVNEPI ---TR----- -----EYSAE V-HNNLLEI- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------HLYW ---------- ----SGKGSI LY-------- ----PSDNYG PLISAITVTL DQSHLSHGVL VGISGSALLF LI--LFIVFS WM-------- YQDK------ ------L--- -----RR--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --------EE LE-------L IEF------Y PGGL-----Y NYQKIKAAT- NNFHDGR-RL GEGGF-GTVY EGTL--LDG- T-AIAVKKLS TTK------- ---------- -EGMNEFVEK SRTI----AG M-KHPNLVTL MGCCAG---- ----KNQLLL VYEYIGTKSL EDALFGSEEL ---------- -------RA- ------SL-- DW--PTRYRI CLGLAEGLAF LHEGSKL-E- IIHGNIRPAN ILL----DD- DL-NPKIYDF GFAKLYHKQK ---------- ---------- ---------- ---------- --------SE GTMSYTAP-- ---------- ---------- ------EVK- ---------- -DRA---LEA S-ADVYSFGV 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---------- -----PSCRM YVGRSEG--- ----CAQMR- ---------- --CRCGCNFC YKC------- ---------- ---GAYSSDH Y-CN------ CCG------- ---------- ---------- -----T---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC01H1G4036.2 -------MMD QWVLGILG-- ---------S ASVFL----- ---------- ---------- -CLIGLL--- ---------- ---------- ---------L VPVYGNTEGD ---------A LNALKTT-L- ADPN------ NVL------- --QS-W---- ------D--- ---------- -----PTLVN -P-------- -------C-- ---------- ---------- ---------- --------T- WFHVT----- ---------- --------C- -----N-S-- EN-------- ---------- ---------- S-VTR----- ---------- ---------- -VDLG----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -NANLSGQLV P--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -------QLG ---------- ---------- ---------- ---------- ---------- ---QL----- ---------- 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ALLCTQSSPM ERP------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---KMSEVV- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -RMLEG---- ---------- ---------- ---------- -DGLAERW-- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --EEWQKEE- ---------- --------MF RQDFNHAHHP ---------- ---------- ------HTDW IIADSTYN-- ---------- ---------- ---------- ---------- ---------- ---------L RPDELSG--- -----PR--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----- RHC02H1G1482.2 ---------- ---------- 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LEGE--LPVS ---------- ---------- ---LS----- GLVNLEDFRI SDNNLSG--- ---------- PIPDFI---- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------E K--WKQLT-K LELHATG-LE GPIPLSI--- ---------- ---------- ---------- ---------- -----SLLNM LTDLRISDI- ---------- ------KGPM HEF-PP---- ---------- ---------- -LINMTD--- LERLVLRNCN L------SGV I-PG-YIW-- KLKT------ ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----IQTLDV SFNK------ ---------- ---------- ---------- ---------- --LI------ -G-------- ---------- ---------- ---------- ---TI-PDDI SARSMLKF-- VFLSG----- ---------- ---------N MLSGDIP-A- ---SILK--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- -----NGIN- ---------- ---------- ---------- ---------- ---------- -VDLSYNNFT WQG--PEQP- ACRQNTNY-- ---------- ---------- ---------- ---------- ---------- ---------- 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D--------- ------F--- ---VRLFQ-- ---------- ---------- ---------- -------L-N LSNN--KFGQ KIPKEIGRI- ---------T HLTV-LDLSH NLL-DGEI-- ------PA-- ---------- ---------- ---------- ---------- --------E- ---------- ---------- ----LASLLD LSNLNLSH-- -----NGLSG RIPKELESLT GLLDVVLSYN D-L-EGPIPN ---NK-AFMN AS----LE-- --GNK----- ---------- --------GL CGNVTGFQ-- ---------P CKK------P ---------- ---------- ---------- ---------- SSV--VKKHP ----IAK--- -----GRKLI LITVLPVMG- ---------- ----ALVLLC VF--IGVLFM C--------- NKRR------ ---------- -----RV-K- -DV------- ---------- -----ERRDG ---------- ---------- ---------- -------D-G W--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --------LS IS-------M LDG------- -------K-A LYRDILNAT- EEFDAKF-CI GQGGH-GSVY KVNL--PLL- G-DIAVKRLH ----SSFQN- ---------- -THPKSFINE VRAL----TG I-KHRNIVNL YGYCSK---- ----AQHSLL VYEYVERGSL SSILSN---- ---------- -------EV- ESK---KL-- DW--LKRVNI IKGVAFALSY MHQDCSP-P- 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---------- ----EALGNV AG-------- --------R- ---------- ---------- ---------- ---------- ------KLLR VSS------- ---------- ---------- ---------- ---------- ---------- ---------- -------FSV LNN------- --------FQ KQFL------ --------P- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------V-FR ---------- ---------- ---------- ---------- -------LLD RREV--AVEN SAPSSSPS-- ---------- ---------- ---------- PS----PS-- ---------- ---------- ---------- ---------- ---PSLSPS- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ------PTPA I--------- ---T------ --AEP----- ---------- --------HM AHSPRSS--- ---------P SPS------- ---------- ------SLPS ---------- ---------- ----PAENSS RV-EDAR--- ----RSNHRV LILSAAIG-- ---------- -----GSVLL II--LITGTI VF-------- ---------- ---------- -----RS-NK MAV------- 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