Family: CAP

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Lineage coverage
Species 
22.38%
Genus 
8.75%
Family 
5%
Order 
8.89%
Class 
16.67%
Phylum 
25%

Description:
Cysteine-rich secretory protein family (CAP) is a large family of cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 protein. This is an RLK family with an uncommon extracellular domain. The hidden Markov model (HMM) PF00188 was used for the CAP classification.

References:
1. New knowledge from old: in silico discovery of novel protein domains in Streptomyces coelicolor. Yeats C, Bentley S, Bateman A. BMC Microbiol. 3, 3, (2003). PMID: 12625841.
2. Isolation and characterization of a cone snail protease with homology to CRISP proteins of the pathogenesis-related protein superfamily. Milne TJ, Abbenante G, Tyndall JD, Halliday J, Lewis RJ. J. Biol. Chem. 278, 31105-10, (2003). PMID: 12759345.
3. The CAP superfamily: cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins--roles in reproduction, cancer, and immune defense. Gibbs GM, Roelants K, O'Bryan MK. Endocr. Rev. 29, 865-97, (2008). PMID: 18824526.
4. NMR solution structure of the pathogenesis-related protein P14a. Fernandez C, Szyperski T, Bruyere T, Ramage P, Mosinger E, Wuthrich K. J. Mol. Biol. 266, 576-93, (1997). PMID: 9067611.

List of CAP in RLKomes

CAP in Arabidopsis thaliana (3702.GCA_000001735.1)

Genetic map for RLKs in reference sequences with length > 1MB

No linkage map is available.

Protein sequence length distribution of CAP family

Summary of function domain topology distribution for CAP family

Domain topology percentage

Domain word cloud

Spatial structure

RLK list
(Click RLK IDs to see its details in the RLK page or click Gene ID to explore its details in its original database. click cDNA, CDS or Prteoin button to download its corresponding sequences.)
Phylogenetic tree
Explore the evolutionary relationships of the CAP family members in phylogenetic tree

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Zoom in on sequence alignments
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Contact: Jinding Liu, biotec(At)njau.edu.cn
©Bioinformatics Center and Plant Phytophthora Interaction Laboratory, Nanjing Agricultural University