Family: G-LecRLK
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Description:
The lectin RLKs play crucial roles in saccharide signaling and are grouped into three RLK families based on the distinct lectin domains: G-, L-, and C-type LecRLK (Vaid et al., 2013). G-LecRLK is also known as S-domain RLK, has an ECD containing an a-mannose binding bulb-type lectin domain, a PAN (Plasminogen/Apple/Nematode), and/or an EGF (Epidermal Growth Factor) domain. The maize ZmPK1 gene that was reported in 1990 is the first described plant RLK (Zhang and Walker, 1990). Other well-known G-LecRLKs includes LORE that regulates lipopolysaccharide immune sensing (Ranf et al., 2015) and SRKs that mediate self-incompatibility (Iwano and Takayama, 2011). G-LecRLKs are also involved in plant-microbe symbiosis (Sun et al., 2020).The hidden Markov models (HMMs) used for the G-LecRLK classification include: PF01453, PF00954, PF08276, PF00024, and PF14295.
References:
1. Iwano M, Takayama S. 2011. Self/non-self discrimination in angiosperm self-incompatibility. Curr Opin Plant Biol. 15(1):78-83. doi: 10.1016/j.pbi.2011.09.003. PMID: 21968124.
2. Ranf S, Gisch N, Sch?ffer M, Illig T, Westphal L, Knirel YA, Sanchez-Carballo PM, Z?hringer U, Huckelhoven R, Lee J, Scheel D. 2015. A lectin S-domain receptor kinase mediates lipopolysaccharide sensing in Arabidopsis thaliana. Nat Immunol. 16(4):426-33. doi: 10.1038/ni.3124. PMID: 25729922.
3. Sun Y, Qiao Z, Muchero W, Chen JG. 2020. Lectin receptor-like kinases: The sensor and mediator at the plant cell surface. Front Plant Sci. 11:596301. doi: 10.3389/fpls.2020.596301. PMID: 33362827.
4. Vaid N, Macovei A, Tuteja N. 2013. Knights in action: Lectin receptor-like kinases in plant development and stress responses. Mol Plant. 6(5):1405-18. doi: 10.1093/mp/sst033. PMID: 23430046.
5. Walker JC, Zhang R. 1990. Relationship of a putative receptor protein kinase from maize to the S-locus glycoproteins of Brassica. Nature. 345(6277):743-6. doi: 10.1038/345743a0. PMID: 2163028.
List of G-LecRLK in RLKomes
G-LecRLK in Arabidopsis thaliana (3702.GCA_000001735.1)
Protein sequence length distribution of G-LecRLK family
Summary of function domain topology distribution for G-LecRLK family
Domain topology percentage
-PF01453-PF00954-PF08276-TM-Kinase-PF11883- |
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-PF01453-PF00954-PF08276-TM-PF12398-Kinase-PF11883- |
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-PF00954-PF00954-PF08276-TM-Kinase-PF11883- |
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-PF01453-PF00954-PF08276-TM-Kinase- |
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-PF01453-PF01453-PF01453-TM-Kinase- |
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-PF01453-PF08276-TM-Kinase- |
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-PF01453-PF01453-PF08276-TM-Kinase-PF11883- |
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-PF01453-PF00954-PF00954-TM-Kinase-PF11883- |
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-PF01453-PF01453-PF14295-TM-Kinase- |
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-PF01453-PF00954-PF00954-TM-Kinase- |
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-PF01453-PF01453-TM-Kinase- |
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-PF01453-PF00954-PF08276-TM-Kinase-PF01453- |
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-PF01453-PF00954-PF08276-PF13947-PF00954-TM-Kinase-PF11883- |
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-PF01453-TM-Kinase- |
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Domain word cloud
Spatial structure