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Description:
Glycoside hydrolase family 18 (GH18) is a type of plant chitinase. This is an RLK family with uncommon extracellular domain. The hidden Markov model (HMM) PF00704 was used for the GH18 classification.

References:
1.Structures and mechanisms of glycosyl hydrolases. Davies G, Henrissat B. Structure 3, 853-9, (1995). PMID: 8535779. 2.Conserved catalytic machinery and the prediction of a common fold for several families of glycosyl hydrolases. Henrissat B, Callebaut I, Fabrega S, Lehn P, Mornon JP, Davies G. Proc. Natl. Acad. Sci. U.S.A. 92, 7090-4, (1995). PMID: 7624375.
3.Chitinase-like proteins in lung injury, repair, and metastasis. Lee CG, Dela Cruz CS, Ma B, Ahangari F, Zhou Y, Halaban R, Sznol M, Elias JA. Proc Am Thorac Soc 9, 57-61, (2012). PMID: 22550243.
4.Structure of chitinase D from Serratia proteamaculans reveals the structural basis of its dual action of hydrolysis and transglycosylation. Madhuprakash J, Singh A, Kumar S, Sinha M, Kaur P, Sharma S, Podile AR, Singh TP. Int J Biochem Mol Biol 4, 166-78, (2013). PMID: 24380021.
5.High resolution crystal structure of the endo-N-Acetyl-a-D-glucosaminidase responsible for the deglycosylation of Hypocrea jecorina cellulases. Stals I, Karkehabadi S, Kim S, Ward M, Van Landschoot A, Devreese B, Sandgren M. PLoS ONE 7, e40854, (2012). PMID: 22859955.
6.Human YKL-39 is a pseudo-chitinase with retained chitooligosaccharide-binding properties. Schimpl M, Rush CL, Betou M, Eggleston IM, Recklies AD, van Aalten DM. Biochem. J. 446, 149-57, (2012). PMID: 22742450.