Family: L-LecRLK
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Description:
Plant RLKs that contain a legume lectin extracellular domain are classified into the L-LecRLK family (Vaid et al., 2013). Interestingly, functionally characterized L-LecRLKs are associated with plant immunity, while few L-LecRLKs regulate plant development or abiotic stress tolerance (Wang and Bouwmeester, 2017). Most studied L-LecRLKs are two immune receptors that sense damage-associated molecular patterns (DAMPs). These include DORN1, which detects extracellular adenosine 5'-triphosphate (eATP) (Choi et al., 2014) and the receptor of extracellular nicotinamide adenine dinucleotide (eNAD+), LecR-VI.2 (Wang et al., 2019). The hidden Markov model (HMM) PF00139 was used for the L-LecRLK classification.
References:
1. Choi J, Tanaka K, Cao Y, Qi Y, Qiu J, Liang Y, Lee SY, Stacey G. 2014. Identification of a plant receptor for extracellular ATP. Science. 343(6168):290-4. doi: 10.1126/science.343.6168.290. PMID: 24436418.
2. Vaid N, Macovei A, Tuteja N. 2013. Knights in action: Lectin receptor-like kinases in plant development and stress responses. Mol Plant. 6(5):1405-18. doi: 10.1093/mp/sst033. PMID: 23430046.
3. Wang C, Huang X, Li Q, Zhang Y, Li JL, Mou Z. 2019. Extracellular pyridine nucleotides trigger plant systemic immunity through a lectin receptor kinase/BAK1 complex. Nat Commun. 10(1):4810. doi: 10.1038/s41467-019-12781-7. PMID: 31641112.
4. Wang Y, Bouwmeester K. 2017. L-type lectin receptor kinases: New forces in plant immunity. PLoS Pathog. 13(8):e1006433. doi: 10.1371/journal.ppat.1006433. PMID: 28817713.
List of L-LecRLK in RLKomes
L-LecRLK in Arabidopsis thaliana (3702.GCA_000001735.1)
Protein sequence length distribution of L-LecRLK family
Summary of function domain topology distribution for L-LecRLK family
Domain topology percentage
-PF00139-TM-Kinase- |
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-PF00139-PF00139-TM-Kinase- |
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Domain word cloud
Spatial structure